irinotecan - Robuta Search

https://www.cancerresearchuk.org/about-cancer/find-a-clinical-trial/a-trial-looking-at-irinotecan-for-children-and-young-people-with-high-risk-ewings-sarcoma-or-primitive-neuroectodermal-tumour A trial looking at irinotecan for children and young people with high risk Ewing's sarcoma or... This trial looked at a chemotherapy drug called irinotecan (also called CPT 11 or Campto). https://pubmed.ncbi.nlm.nih.gov/18334851/?dopt=Abstract Phase II study of a combination of irinotecan and S-1 in patients with advanced gastric cancer... The combination therapy of CPT-11 and S-1 provided prolonged TTP with low toxicity, and the results warrant a further phase III study to define the efficacy in... https://pubmed.ncbi.nlm.nih.gov/31976547/?dopt=Abstract Luteolin prevents irinotecan-induced intestinal mucositis in mice through antioxidant and... Luteolin prevents intestinal mucositis induced by irinotecan and therefore could be a potential adjunct in anti-tumour therapy to control this adverse effect,... luteolin prevents irinotecan induced intestinal https://www.cancerresearchuk.org/about-cancer/find-a-clinical-trial/pair-chemotherapy-with-cisplatin-and-irinotecan-in-advanced-pancreatic-cancer A trial looking at cisplatin and irinotecan for advanced pancreatic cancer (PAIR) This trial looked at a new combination of chemotherapy with cisplatin and irinotecan for people with advanced pancreatic cancer. It recruited people who hadn' looking at https://profiles.wustl.edu/en/publications/liposomal-irinotecan-and-5-fluorouracilleucovorin-in-older-patien/ Liposomal irinotecan and 5-fluorouracil/leucovorin in older patients with metastatic pancreatic... https://research.birmingham.ac.uk/en/publications/a-randomized-trial-comparing-defined-duration-with-continuous-iri/ A randomized trial comparing defined-duration with continuous irinotecan until disease progression... https://pubmed.ncbi.nlm.nih.gov/11510032/ Beyond pancreatic cancer: irinotecan and gemcitabine in solid tumors and hematologic malignancies Non-platinum combinations including gemcitabine and irinotecan (Gemzar; Eli Lilly and Company, Indianapolis, IN) for the management of a variety of... pancreatic cancer solid tumors beyond irinotecan https://adisinsight.springer.com/drugsafety/803159931?error=cookies_not_supported&code=907cfee6-72c6-4dbf-b792-44e8da5006b5 Irinotecan - AdisInsight In a retrospective study, one patient [age and sex not stated] experienced failure to thrive during therapy with irinotecan. The patient, who had a history of irinotecan adisinsight https://seer.cancer.gov/oncologytoolbox/canmed/ndconc/70700-0170/ 70700-0170 Irinotecan hydrochloride - CanMED: NDC CanMED: NDC. The Cancer Medications Enquiry Database (CanMED) is a two-part resource for cancer drug treatment related studies. irinotecan hydrochloride ndc https://researchconnect.buffalo.edu/en/publications/in-vitro-and-in-vivo-irinotecan-induced-changes-in-expression-pro/ In vitro and in vivo irinotecan-induced changes in expression profiles of cell cycle and... in vitro https://fis.tu-dresden.de/portal/en/publications/nanoliposomal-irinotecan-and-fluorouracil-plus-leucovorin-versus-fluorouracil-plus-leucovorin-in-patients-with-cholangiocarcinoma-and-gallbladder-carcinoma-previously-treated-with-gemcitabinebased-therapies-aio-naliricc(accf63dd-ca8c-411d-97af-e5a5739576cf).html Nanoliposomal irinotecan and fluorouracil plus leucovorin versus fluorouracil plus leucovorin in... irinotecan fluorouracil plus leucovorin versus https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2011.00052/full Frontiers | Phase I Study of Celecoxib with Concurrent Irinotecan, Cisplatin, and Radiation Therapy... Purpose: Preclinical findings suggest that adding targeted therapies to combination radiation-chemotherapy can enhance treatment efficacy; however, this appr... phase i study https://adisinsight.springer.com/trials/700384577?error=cookies_not_supported&code=e43e8601-c9fa-4a49-98d4-a9035fb89593 A Randomized Controlled Study Comparing the Safety and Efficacy of Irinotecan Hydrochloride... This study is a randomized, controlled, multicenter, prospective clinical trial with a planned enrollment of 74 patients, who will be randomly assigned in a 2:1 safety and efficacy https://edrn.cancer.gov/data-and-resources/publications/24859205-cpg-island-methylator-phenotype-is-associated-with-response-to-adjuvant-irinotecan-based-therapy-for-stage-iii-colon-cancer/ CpG island methylator phenotype is associated with response to adjuvant irinotecan-based therapy... This is a publication by a member of the Early Detection Research Network. is associated with https://researchconnect.buffalo.edu/en/publications/a-phase-ii-study-of-high-dose-cetuximab-plus-irinotecan-in-colore/ A Phase II Study of High-Dose Cetuximab plus Irinotecan in Colorectal Cancer Patients with KRAS... https://scholars.duke.edu/publication/726628 Scholars@Duke publication: Phase I dose escalation study of gemcitabine plus irinotecan in advanced... https://pubmed.ncbi.nlm.nih.gov/19190131/ Marked activity of irinotecan and rapamycin combination toward colon cancer cells in vivo and in... These results identify HIF-1alpha as a promising target and provide a rationale for clinical trials of low-dose irinotecan and rapamycin combination toward... https://pubmed.ncbi.nlm.nih.gov/20958992/ "Poker" association of weekly alternating 5-fluorouracil, irinotecan, bevacizumab and oxaliplatin... Osservatorio Nazionale sulla Sperimentazione Clinica dei Medicinali (OsSC) Agenzia Italiana del Farmaco (AIFA) Numero EudraCT 2007-004946-34. poker association weekly alternating https://pubmed.ncbi.nlm.nih.gov/20038727/ Genotype-driven phase I study of irinotecan administered in combination with... PURPOSE We aimed to identify the maximum-tolerated dose (MTD) of irinotecan in patients with cancer with UGT1A1*1/*1 and *1/*28 genotypes. We hypothesize that... phase i study genotype driven https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2022.756078/full Frontiers | Effectiveness and Cost-Utility Analysis of Different Doses of Irinotecan Plus... Objective: Patients with metastatic colorectal cancer (mCRC) had oncological benefits with irinotecan dose escalation of FOLFIRI regimen combined with bevaci... utility analysis frontiers effectiveness cost https://adisinsight.springer.com/drugsafety/803267680?error=cookies_not_supported&code=e2665faa-b92b-4eda-86dc-47586bb7e5a7 Irinotecan - AdisInsight A 48-year-old man developed acute pancreatitis following irinotecan treatment.The man, with poorly differentiated metastatic rectal small cell neuroendocrine irinotecan adisinsight https://seer.cancer.gov/oncologytoolbox/canmed/ndconc/25021-0230/ 25021-0230 Irinotecan Hydrochloride - CanMED: NDC CanMED: NDC. The Cancer Medications Enquiry Database (CanMED) is a two-part resource for cancer drug treatment related studies. irinotecan hydrochloride ndc https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2021.795381/full Frontiers | Triple-Regimen of Vemurafenib, Irinotecan, and Cetuximab for the Treatment of... Mutation of the BRAF proto-oncogene is found in approximately 10% of colorectal cancers (CRC), with much of the mutation conferred by a V600E mutation. Unlik... for the frontiers triple regimen vemurafenib https://adisinsight.springer.com/drugsafety/803062576?error=cookies_not_supported&code=dc2fcec0-11bc-4a3f-ba04-c72a91fd536a Irinotecan - AdisInsight A 40-year-old woman with sigmoid colon cancer developed dysarthria during treatment with irinotecan.The woman started receiving chemotherapy according to a irinotecan adisinsight https://www.cancerresearchuk.org/about-cancer/find-a-clinical-trial/a-trial-looking-irinotecan-beads-bowel-cancer-spread-liver-paragon-ii Cancer Research UK | A trial looking at using irinotecan beads for bowel cancer that had spread to... This trial looked at using irinotecan beads to treat bowel cancer that had spread to the liver, before having surgery to remove it. https://seer.cancer.gov/oncologytoolbox/canmed/ndconc/47335-0953/ 47335-0953 Irinotecan Hydrochloride - CanMED: NDC CanMED: NDC. The Cancer Medications Enquiry Database (CanMED) is a two-part resource for cancer drug treatment related studies. irinotecan hydrochloride ndc https://pubmed.ncbi.nlm.nih.gov/21859559/ A phase I study of the chinese herbal medicine PHY906 as a modulator of irinotecan-based... PHY906 is a novel Chinese herbal preparation that has been used in the Orient for over 1800 years to treat a wide range of gastrointestinal side effects... https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=82e95139-6222-f73d-e053-2a91aa0a4810 DailyMed - IRINOTECAN HYDROCHLORIDE injection dailymed irinotecan hydrochloride injection https://adisinsight.springer.com/drugsafety/803928285?error=cookies_not_supported&code=bbe394ef-55fd-4d1e-8124-c26ff916555e Irinotecan/Sacituzumab govitecan - AdisInsight Nine patients [ages and sexes not stated] with metastatic breast cancer experienced severe sacituzumab govitecan-related toxicity. All sacituzumab irinotecan adisinsight https://scholars.duke.edu/publication/709881 Scholars@Duke publication: Irinotecan for malignant mesothelioma A phase II trial by the Cancer and... https://pubmed.ncbi.nlm.nih.gov/29262551/?dopt=Abstract The combination of temozolomide-irinotecan regresses a doxorubicin-resistant patient-derived... The aim of the present study was to determine the usefulness of a patient-derived orthotopic xenograft (PDOX) nude-mouse model of a doxorubicin-resistant... combination temozolomide irinotecan https://pubmed.ncbi.nlm.nih.gov/39487711/ A Phase 1 Study of ABI-009 (Nab-sirolimus) in Combination With Temozolomide and Irinotecan in... ClinicalTrials.gov identifier NCT02975882. https://www.nice.org.uk/guidance/ta307/evidence/review-decision-october-2016-2669052349?tab=evidence Review decision - October 2016 | Aflibercept in combination with irinotecan and fluorouracil-based... Evidence-based recommendations on aflibercept (Zaltrap) with irinotecan and fluorouracil-based therapy (FOLFIRI) for treating metastatic colorectal cancer... https://www.cruk.cam.ac.uk/publications/lack-of-efficacy-of-bevacizumab-irinotecan-in-cases-of-pediatric-recurrent-ependymomaa-pediatric-brain-tumor-consortium-study/ Lack of efficacy of bevacizumab + irinotecan in cases of pediatric recurrent ependymoma-a Pediatric... Authors: S Gururangan, J Fangusaro, T Young Poussaint, A Onar-Thomas, RJ Gilbertson, S Vajapeyam, A Gajjar, S Goldman, HS Friedman, RJ Packer, JM Boyett, LE... lack of efficacy bevacizumab irinotecan https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2023.1138357/full Frontiers | Effectiveness and safety of capecitabine, irinotecan and panitumumab in advanced... Introduction: Capecitabine, irinotecan, and panitumumab (CAPIRI-P) is a controversial regimen for metastatic colorectal cancer, with concerns regarding the e... frontiers effectiveness safety capecitabine irinotecan https://researchconnect.buffalo.edu/en/publications/optimal-sampling-strategies-for-irinotecan-cpt-11-and-its-active-/ Optimal Sampling Strategies for Irinotecan (CPT-11) and its Active Metabolite (SN-38) in Cancer... https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2021.654974/full Frontiers | A Retrospective Analysis of the Effect of Irinotecan-Based Regimens in Patients With... Background At present, patients with metastatic breast cancer (MBC) have few treatment options after receiving anthracyclines and taxanes. Studies have shown... https://pubmed.ncbi.nlm.nih.gov/32343642/ Irinotecan, Temozolomide, and Dinutuximab With GM-CSF in Children With Refractory or Relapsed... I/T/DIN/GM-CSF has significant antitumor activity in patients with relapsed/refractory neuroblastoma. Study of chemoimmunotherapy in the frontline setting is... https://www.cancer.gov/research/participate/clinical-trials-search/v?id=NCI-2024-09567 NANT 2021-01 Phase II STING (Sequential Temozolomide, Irinotecan, NK Cells and GD2 mAb) Trial - NCI NANT 2021-01 Phase II STING (Sequential Temozolomide, Irinotecan, NK Cells and GD2 mAb) Trial https://www.cancerresearchuk.org/about-cancer/treatment/drugs/aflibercept-folfiri Aflibercept and folinic acid, fluorouracil and irinotecan (FOLFIRI) | Cancer Research UK Aflibercept and folinic acid, fluorouracil, and irinotecan (FOLFIRI) is a cancer drug combination. It is a treatment for some people with colorectal cancer... folinic acid cancer research aflibercept fluorouracil irinotecan https://seer.cancer.gov/oncologytoolbox/canmed/ndconc/60505-6272/ 60505-6272 Irinotecan Hydrochloride - CanMED: NDC CanMED: NDC. The Cancer Medications Enquiry Database (CanMED) is a two-part resource for cancer drug treatment related studies. irinotecan hydrochloride ndc https://adisinsight.springer.com/trials/700392189?error=cookies_not_supported&code=b48441c3-957c-4114-85eb-9d9be9ee2178 Short-Course Radiotherapy Followed by Liposomal Irinotecan, Capecitabine, and Camrelizumab as... This study is for adults with locally advanced rectal cancer that has not spread to distant organs, and is classified as pMMR or MSS (which means it typically short course followed by radiotherapy https://www.cancerresearchuk.org/about-cancer/treatment/drugs/irinotecan Irinotecan (Campto) | Cancer information | Cancer Research UK Irinotecan is a type of chemotherapy. It is a treatment for bowel cancer. Find out about how you have it, possible side effects and other important information. cancer information irinotecan research uk