Robuta

https://www.ncbi.nlm.nih.gov/Structure/pdb/5YFN 5YFN: Human isocitrate dehydrogenase 1 bound with isocitrate Isocitrate dehydrogenase [NADP] cytoplasmicISOCITRIC ACIDMAGNESIUM IONPOTASSIUM ION isocitrate dehydrogenase 1humanbound https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2020.00189/full Frontiers | Mutation of Isocitrate Dehydrogenase 1 in Cholangiocarcinoma Impairs Tumor Progression... Aim: Isocitrate dehydrogenase 1 (IDH1) is key enzyme involved in cellular metabolism and DNA repair. Mutations in IDH1 occur in up to 25% of cholangiocarcino... isocitrate dehydrogenase 1frontiersmutation