isogenic - Robuta Search

https://pubmed.ncbi.nlm.nih.gov/38405931/

iSCORE-PD: an isogenic stem cell collection to research Parkinson's Disease

Parkinson's disease (PD) is a neurodegenerative disorder caused by complex genetic and environmental factors. Genome-edited human pluripotent stem cells...

stem cell iscore pd isogenic collection

https://pubmed.ncbi.nlm.nih.gov/12438652/

Gene expression profiling of isogenic cells with different TP53 gene dosage reveals numerous genes...

TP53 does not fully comply with the Knudson model [Knudson, A. G., Jr. (1971) Proc. Natl. Acad. Sci. USA 68, 820-823] in that a reduction of constitutional...

gene expression profiling isogenic cells different

https://pubmed.ncbi.nlm.nih.gov/38353623/

Generation of Human Isogenic Induced Pluripotent Stem Cell Lines with CRISPR Prime Editing

We developed an efficient CRISPR prime editing protocol and generated isogenic-induced pluripotent stem cell (iPSC) lines carrying heterozygous or homozygous...

induced pluripotent stem cell lines generation human isogenic