ligases - Robuta Search

https://pubmed.ncbi.nlm.nih.gov/34943817/ Potential of E3 Ubiquitin Ligases in Cancer Immunity: Opportunities and Challenges Cancer immunotherapies, including immune checkpoint inhibitors and immune pathway-targeted therapies, are promising clinical strategies for treating cancer.... ubiquitin ligases potential https://pubchem.ncbi.nlm.nih.gov/protein/EC:6.3.5.- Carbon--nitrogen ligases with glutamine as amido-N-donor (EC 6.3.5.-) | Protein Target - PubChem Protein enzyme information for 6.-.-.- Ligases | 6.3.-.- Forming carbon-nitrogen bonds. Find compounds, bioassays, and pathways associated with this enzyme. https://pubmed.ncbi.nlm.nih.gov/12909715/ Glutathione synthetase homologs encode alpha-L-glutamate ligases for methanogenic coenzyme F420 and... Proteins in the ATP-grasp superfamily of amide bond-forming ligases have evolved to function in a number of unrelated biosynthetic pathways. Previously... https://theses.gla.ac.uk/82641/ Structural insights into ADP-ribosylation of ubiquitin C-terminus by Deltex E3 ligases - Enlighten... https://data.mendeley.com/datasets/wd8mp6t629/1 Bacterial ligases reveal fundamental principles of polyubiquitin specificity - Mendeley Data Extended data containing full protein gels. Associated with https://doi.org/10.1016/j.molcel.2023.11.017. fundamental principles bacterial ligases reveal specificity https://vivo.colorado.edu/display/meshid_D08.811.464.754 Polynucleotide Ligases | CU Experts | CU Boulder polynucleotide ligases cu experts boulder https://experts.mcmaster.ca/scholarly-works/178320 d-Ala-d-Ala ligases from glycopeptide... Learn about the scholarly work entitled d-Ala-d-Ala ligases from glycopeptide... ala ligases https://www.wikidata.org/wiki/Q27626747 Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligases - Wikidata https://www.ibv.csic.es/training-network-in-drug-discovery-targeting-trim-ubiquitin-ligases-in-disease-trim-net/ TRAINING NETWORK IN DRUG DISCOVERY TARGETING TRIM UBIQUITIN LIGASES IN DISEASE (TRIM-NET) -... training network drug discovery ubiquitin ligases https://pubmed.ncbi.nlm.nih.gov/25499913/ AMBRA1 interplay with cullin E3 ubiquitin ligases regulates autophagy dynamics Autophagy maintains cellular homeostasis by degrading harmful or unnecessary intracellular components. How the autophagy response is induced rapidly and... ubiquitin ligases interplay autophagy dynamics https://cordis.europa.eu/project/id/101040046 Chemical rewiring of E3 ubiquitin ligases as a generalizable therapeutic approach | TrickE3 |... Classical drug design relies mostly on the availability of accessible pockets to block specific protein activities. Despite tremendous progress, more than 80%... ubiquitin ligases https://pubmed.ncbi.nlm.nih.gov/11846380/ Thermus scotoductus and Rhodothermus marinus DNA ligases have higher ligation efficiencies than... To mimic large numbers of nicked DNA duplexes we used a technique that produces nicked duplex DNA substrates by hybridization of complementary... dna ligases https://www.helsinki.fi/en/researchgroups/plant-phenomics/news/genomic-and-phenomic-screens-for-flower-related-ring-type-ubiquitin-e3-ligases-in-arabidopsis Genomic and Phenomic Screens for Flower Related RING Type Ubiquitin E3 Ligases in Arabidopsis |... Our latest publication using the National Plant Phenotyping Infrastructure https://cordis.europa.eu/project/id/851478 Therapeutic hijacking of E3 Ligases | Glue2Degrade | Project | Fact Sheet | H2020 | CORDIS |... Traditional drug design relies on inhibition of enzymes or receptors with accessible hydrophobic pockets. The concept of proteolysis targeting chimeras... project fact sheet therapeutic hijacking ligases https://pubmed.ncbi.nlm.nih.gov/20348096/ Allosteric regulation of the ubiquitin:NIK and ubiquitin:TRAF3 E3 ligases by the lymphotoxin-beta... The lymphotoxin-beta receptor (LTbetaR) activates the NF-kappaB2 transcription factors, p100 and RelB, by regulating the NF-kappaB-inducing kinase (NIK).... https://tobias-lib.ub.uni-tuebingen.de/xmlui/handle/10900/90079 Developing Small-Molecule Inhibitors of HECT-Type Ubiquitin Ligases for Therapeutic Applications:... small molecule inhibitors https://pubmed.ncbi.nlm.nih.gov/38416790/ Plasmodium falciparum contains functional SCF and CRL4 ubiquitin E3 ligases, and CRL4 is critical... Protein ubiquitination is essential for cellular homeostasis and regulation of several processes, including cell division and genome integrity. Ubiquitin E3... plasmodium falciparum https://scholarworks.gsu.edu/items/af599f00-ec65-496d-9e78-17a3b6dd874c Profiling Substrates of HECT and U-box E3 Ligases via Orthogonal Ubiquitin Transfer Cascade and... https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2023.1123244/full Frontiers | The E3 ubiquitin ligases regulate PD-1/PD-L1 protein levels in tumor microenvironment... The tumor microenvironment (TME) is the tumor surrounding environment, which is critical for tumor development and progression. TME is also involved in clini... https://cordis.europa.eu/project/id/813599/reporting/es Training network in drug discovery targeting TRIM Ubiquitin ligases in disease | H2020 | CORDIS |... Latest report summary training network drug discovery https://www.mordorintelligence.com/industry-reports/ligases-enzyme-market Ligases Enzyme Market - Share & Size The Ligases Enzyme Market is growing at a CAGR of 5.5% over the next 5 years. Becton, Dickinson and Company, Agilent Technologies, Merck KGaA, Thermo Fisher... market share ligases enzyme size https://www.frontiersin.org/journals/plant-science/articles/10.3389/fpls.2018.00139/full Frontiers | Roles of E3 Ubiquitin-Ligases in Nuclear Protein Homeostasis during Plant Stress... Ubiquitination, the reversible protein conjugation with ubiquitin (Ub), is a post-translational modification that enables rapid and specific cellular respons... https://dna-ligases.com/ Evolution of DNA ligases of Nucleo-Cytoplasmic Large DNA viruses dna ligases evolution nucleo cytoplasmic large https://data.mendeley.com/datasets/jpcwgwszz4/1 Source Data: Molecular mechanisms of CAND2 in regulating SCF ubiquitin ligases - Mendeley Data Source data for the published research article. source data https://peace.studentorg.berkeley.edu/2015/03/13/ubiquinin-ligases/ Ubiquinin Ligases | PEACE at UC Berkeley ligases peace uc berkeley https://www.ncbi.nlm.nih.gov/mesh?Db=mesh&Cmd=ShowDetailView&TermToSearch=68019733 Carbon-Nitrogen Ligases with Glutamine as Amide-N-Donor - MeSH - NCBI carbon nitrogen ligases glutamine https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2012.00029/full Frontiers | CRL Ubiquitin Ligases and DNA Damage Response Cullin/RING ubiquitin ligases (CRL) comprise the largest subfamily of ubiquitin ligases and are involved in various biological processes. One of the main fun... ubiquitin ligases dna damage frontiers crl response https://experts.arizona.edu/en/publications/development-of-non-electrophoretic-assay-method-for-dna-ligases-a/ Development of non-electrophoretic assay method for DNA ligases and its application to screening of...