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https://www.aafp.org/afp/2019/0315/p392 Lofexidine (Lucemyra) for Treatment of Opioid Withdrawal Symptoms | AFP Lofexidine has been shown to be as effective as clonidine at controlling some of the symptoms of withdrawal from opioid use. It may have a small additional... opioid withdrawal symptomslofexidinelucemyratreatmentafp