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Jerkmate
https://spirochem.com/technology/new-modalities/macrocycles
Macrocycles | SpiroChem
Small molecules with a lot of potential. Macrocycles are compelling entities in drug discovery with unique properties. Complex chemistry challenges. Learn more!
macrocyclesspirochem
https://www.sygnaturediscovery.com/modalities/peptides/
Peptides and Macrocycles
Feb 23, 2026 - Sygnature Discovery accelerates peptide drug discovery with integrated design, synthesis, analytics, and in vivo support.
peptidesmacrocycles
https://www.nature.com/articles/s41589-025-01929-w?error=cookies_not_supported&code=9620fada-e9cd-4d5b-89da-493b328134f9
Accurate de novo design of high-affinity protein-binding macrocycles using deep learning | Nature...
Jun 20, 2025 - Developing macrocyclic binders to therapeutic proteins typically relies on large-scale screening methods that are resource intensive and provide little control...
using deep learningnovo designaccuratehighaffinity