Robuta

https://pubmed.ncbi.nlm.nih.gov/40223119/ The RBM39 degrader indisulam inhibits acute megakaryoblastic leukemia by altering the alternative... Indisulam is a promising therapeutic candidate for AMKL and the RBM39-mediated ZMYND8 splicing plays an important role in promoting the development of AMKL. degrader https://pubmed.ncbi.nlm.nih.gov/7589286/?ordinalpos=6&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum Establishment and characterization of a novel human immature megakaryoblastic leukemia cell line,... A novel fibroblast-dependent human immature megakaryoblastic leukemia cell line (M-MOK) was established from the bone marrow of a girl with acute... of a