https://pdb101.rcsb.org/motm/106
PDB-101: Molecule of the Month: Poly(A) Polymerase
Poly(A) polymerase adds a long tail of adenine nucleotides at the end of messenger RNA
molecule of the monthpdbpoly
https://pdb101.rcsb.org/motm/39
PDB-101: Molecule of the Month: lac Repressor
A genetic circuit controls the production of lactose-utilizing enzymes in bacteria
molecule of the monthpdblac
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https://pdb101.rcsb.org/motm/motm-about
PDB-101: About Molecule of the Month
PDB-101: Training, Outreach, and Education portal of RCSB PDB
molecule of the monthpdb
https://pdb101.rcsb.org/motm/299
PDB-101: Molecule of the Month: Malaria Parasite PTEX
The parasite that causes malaria exports hundreds of proteins to remodel the cells that it infects.
molecule of the monthpdbmalariaparasiteptex
https://pdb101.rcsb.org/motm/287
PDB-101: Molecule of the Month: ZAR1 Resistosome
Plants protect themselves from infection with immune system machines such as the resistosome
molecule of the monthpdb
https://pdb101.rcsb.org/motm/87
PDB-101: Molecule of the Month: Zinc Fingers
Zinc ions are used to strengthen small protein modules that recognize DNA
molecule of the monthzinc fingerspdb
https://pdb101.rcsb.org/motm/38
PDB-101: Molecule of the Month: Potassium Channels
Potassium channels allow potassium ions to pass, but block smaller sodium ions
molecule of the monthpdbpotassiumchannels
https://pdb101.rcsb.org/motm/123
PDB-101: Molecule of the Month: P-glycoprotein
P-glycoprotein pumps toxic molecules out of our cells
molecule of the monthpdbglycoprotein
https://pdb101.rcsb.org/motm/302
PDB-101: Molecule of the Month: H5 Hemagglutinin
Sugar-binding protein on the surface of the H5N1 avian influenza virus
molecule of the monthpdbh5
https://pdb101.rcsb.org/motm/199
PDB-101: Molecule of the Month: Monellin
Monellin and other supersweet proteins trick our taste receptors.
molecule of the monthpdb
https://pdb101.rcsb.org/motm/259
PDB-101: Molecule of the Month: Designed Proteins and Citizen Science
What if people with no formal experience in science could help to improve or even rewrite nature, simply by playing a game?
molecule of the monthcitizen sciencepdbdesignedproteins
https://pdb101.rcsb.org/motm/254
PDB-101: Molecule of the Month: Cellulose Synthase
Plants build tough cellulose strands one sugar at a time.
molecule of the monthpdbcellulose
https://pdb101.rcsb.org/motm/55
PDB-101: Molecule of the Month: DNA Ligase
DNA ligase reconnects broken DNA strands, and is used to engineer recombinant DNA
molecule of the monthdna ligasepdb
https://pdb101.rcsb.org/motm/40
PDB-101: Molecule of the Month: RNA Polymerase
RNA polymerase transcribes genetic information from DNA into RNA
molecule of the monthpdbrnapolymerase
https://pdb101.rcsb.org/motm/235
PDB-101: Molecule of the Month: AMPA Receptor
Receptors for the neurotransmitter glutamate in our brain come in several shapes and sizes.
molecule of the monthpdbampareceptor
https://pdb101.rcsb.org/motm/95
PDB-101: Molecule of the Month: Multidrug Resistance Transporters
Many bacteria use multidrug resistance transporters to pump drugs and poisons out of the cell
molecule of the monthpdbresistancetransporters
https://pdb101.rcsb.org/motm/57
PDB-101: Molecule of the Month: Catalase
Catalase protects us from dangerous reactive oxidizing molecules
molecule of the monthpdb
https://pdb101.rcsb.org/motm/237
PDB-101: Molecule of the Month: Nanodiscs and HDL
Nanodiscs conveniently package a small piece of membrane for experimental studies.
molecule of the monthpdbhdl
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https://pdb101.rcsb.org/motm/motm-by-date
PDB-101: Molecule of the Month By Date
PDB-101: Training, Outreach, and Education portal of RCSB PDB
molecule of the monthby datepdb
https://pdb101.rcsb.org/motm/223
PDB-101: Molecule of the Month: Piezo1 Mechanosensitive Channel
Mechanosensitive ion channels give our cells a sense of touch.
molecule of the monthpdbchannel
https://pdb101.rcsb.org/motm/64
PDB-101: Molecule of the Month: Kinesin
The motor protein kinesin carries cellular cargo along microtubules
molecule of the monthpdbkinesin
https://pdb101.rcsb.org/motm/120
PDB-101: Molecule of the Month: Antifreeze Proteins
Small antifreeze proteins protect cells from damage by ice
molecule of the monthpdbantifreezeproteins
https://pdb101.rcsb.org/motm/242
PDB-101: Molecule of the Month: Coronavirus Proteases
Coronavirus proteases are attractive targets for the design of antiviral drugs.
molecule of the monthpdbcoronavirusproteases
https://pdb101.rcsb.org/motm/256
PDB-101: Molecule of the Month: SARS-CoV-2 Spike and Antibodies
Structural biologists are revealing the many ways that antibodies recognize SARS-CoV-2
molecule of the monthpdbsarscovspike
https://pdb101.rcsb.org/motm/113
PDB-101: Molecule of the Month: Influenza Neuraminidase
Neuraminidase is an important target for influenza drugs
molecule of the monthpdbinfluenzaneuraminidase
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https://pdb101.rcsb.org/motm/310
PDB-101: Molecule of the Month: Incretins
GLP-1 and GIP are hormones that are released soon after you eat a meal
molecule of the monthpdbincretins
https://pdb101.rcsb.org/motm/192
PDB-101: Molecule of the Month: Vancomycin
The antibiotic vancomycin blocks the construction of bacterial cell walls.
molecule of the monthpdbvancomycin
https://pdb101.rcsb.org/motm/290
PDB-101: Molecule of the Month: Nanowires
Nanowires conduct electrons one at a time inside biological molecules.
molecule of the monthpdbnanowires
https://pdb101.rcsb.org/motm/201
PDB-101: Molecule of the Month: Isoprene Synthase
Plants release a billion metric tons of isoprene and other organic gases every year.
molecule of the monthpdb
https://pdb101.rcsb.org/motm/249
PDB-101: Molecule of the Month: SARS-CoV-2 RNA-dependent RNA Polymerase
Coronaviruses duplicate their RNA genome using a specialized polymerase
molecule of the monthpdbsarscovrna
https://pdb101.rcsb.org/motm/229
PDB-101: Molecule of the Month: Fluorescent RNA Aptamers
RNA aptamers are being engineered to track molecules inside living cells
molecule of the monthpdbfluorescentrna
https://pdb101.rcsb.org/motm/17
PDB-101: Molecule of the Month: Cyclooxygenase
Aspirin attacks an important enzyme in pain signaling and blood clotting
molecule of the monthpdb
https://pdb101.rcsb.org/motm/262
PDB-101: Molecule of the Month: Fifty Years of Open Access to PDB Structures
The Protein Data Bank is celebrating its golden anniversary!
molecule of the monthfifty yearsopen accesspdb
https://pdb101.rcsb.org/motm/284
PDB-101: Molecule of the Month: ATM and ATR Kinases
Dividing cells use ATM and ATR kinases to respond to DNA damage.
molecule of the monthpdbatmatrkinases
https://pdb101.rcsb.org/motm/150
PDB-101: Molecule of the Month: Sliding Clamps
Sliding clamps slide along DNA strands and keep DNA polymerase on track during replication
molecule of the monthpdbslidingclamps
https://pdb101.rcsb.org/motm/260
PDB-101: Molecule of the Month: Ribonuclease P
The ribozyme ribonuclease P cleaves pre-tRNA to form functional tRNA.
molecule of the monthpdb
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https://pdb101.rcsb.org/motm/243
PDB-101: Molecule of the Month: Voltage-gated Sodium Channels
Voltage-gated sodium channels transmit signals in a wave through the nervous system.
molecule of the monthsodium channelspdbvoltage
https://pdb101.rcsb.org/motm/195
PDB-101: Molecule of the Month: RAF Protein Kinases
A single mutation in a RAF protein kinase can help transform a normal cell into a cancer cell.
molecule of the monthprotein kinasespdbraf
https://pdb101.rcsb.org/motm/222
PDB-101: Molecule of the Month: Proteins and Nanoparticles
Nanotech scientists are designing new ways to combine proteins and nanoparticles
molecule of the monthpdbproteinsnanoparticles
https://pdb101.rcsb.org/motm/246
PDB-101: Molecule of the Month: SARS-CoV-2 Spike
Coronavirus spike protein binds to receptors on cell surfaces, and is a target for vaccine development.
molecule of the monthpdbsarscovspike
https://pdb101.rcsb.org/motm/motm-by-category
PDB-101: Molecule of the Month By Category
PDB-101: Training, Outreach, and Education portal of RCSB PDB
molecule of the monthby categorypdb
https://pdb101.rcsb.org/motm/316
PDB-101: Molecule of the Month: Insect Odorant Receptors
Protein complexes that allow insects to detect a wide variety of volatile compounds
molecule of the monthpdbinsectreceptors
https://pdb101.rcsb.org/motm/198
PDB-101: Molecule of the Month: Beta-galactosidase
Beta-galactosidase is a powerful tool for genetic engineering of bacteria
molecule of the monthpdbbeta
https://pdb101.rcsb.org/motm/289
PDB-101: Molecule of the Month: Mediator
Mediator integrates regulatory information to decide when genes need to be transcribed.
molecule of the monthpdbmediator
https://pdb101.rcsb.org/motm/89
PDB-101: Molecule of the Month: Aconitase and Iron Regulatory Protein 1
Aconitase performs a reaction in the citric acid cycle, and moonlights as a regulatory protein
molecule of the monthpdbironregulatoryprotein
https://pdb101.rcsb.org/motm/191
PDB-101: Molecule of the Month: Glutamate-gated Chloride Receptors
The antibiotic ivermectin attacks glutamate-gated chloride channels, paralyzing parasitic worms.
molecule of the monthpdbglutamatechloridereceptors
https://pdb101.rcsb.org/motm/189
PDB-101: Molecule of the Month: Amyloids
Alzheimer's disease and prion diseases are linked to unnatural aggregation of proteins into amyloid fibrils.
molecule of the monthpdb
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https://pdb101.rcsb.org/motm/265
PDB-101: Molecule of the Month: Golgi Casein Kinase
Casein and many other secreted proteins are phosphorylated by Golgi casein kinase
molecule of the monthcasein kinasepdb
https://pdb101.rcsb.org/motm/264
PDB-101: Molecule of the Month: SARS-CoV-2 Spike Variants
SARS-CoV-2 is constantly changing, posing new challenges during the COVID19 pandemic
molecule of the monthpdbsarscovspike
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https://pdb101.rcsb.org/motm/135
PDB-101: Molecule of the Month: Integrase
HIV integrase allows HIV to insert itself into the genome of an infected cell
molecule of the monthpdbintegrase
https://pdb101.rcsb.org/motm/227
PDB-101: Molecule of the Month: Telomerase
Telomerase maintains the ends of our chromosomes.
molecule of the monthpdbtelomerase
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https://pdb101.rcsb.org/motm/23
PDB-101: Molecule of the Month: DNA
Atomic structures reveal how the iconic double helix encodes genomic information
molecule of the monthpdbdna
https://pdb101.rcsb.org/motm/146
PDB-101: Molecule of the Month: Aminoglycoside Antibiotics
Antibiotic-resistant bacteria build enzymes that destroy drugs like streptomycin
molecule of the monthpdbantibiotics
https://pdb101.rcsb.org/motm/240
PDB-101: Molecule of the Month: Hypoxia-Inducible Factors
HIF-α is a molecular switch that responds to changing oxygen levels.
molecule of the monthpdbhypoxiafactors
https://pdb101.rcsb.org/motm/138
PDB-101: Molecule of the Month: Glucansucrase
Bacteria adhere to our teeth by building sticky sugar chains
molecule of the monthpdb
https://pdb101.rcsb.org/motm/134
PDB-101: Molecule of the Month: Integrin
Integrins forge flexible linkages between the infrastructure inside and outside of cells
molecule of the monthpdbintegrin
https://pdb101.rcsb.org/motm/31
PDB-101: Molecule of the Month: p53 Tumor Suppressor
p53 tumor suppressor protects the body from DNA damage and cancer
molecule of the monthpdbp53tumorsuppressor
https://pdb101.rcsb.org/motm/88
PDB-101: Molecule of the Month: Clathrin
Three-armed clathrin triskelions are used to build molecular cages involved in transport
molecule of the monthpdb
https://pdb101.rcsb.org/motm/185
PDB-101: Molecule of the Month: Titin
The giant protein titin organizes the structure of muscle and gives them elasticity
molecule of the monthpdb
https://pdb101.rcsb.org/motm/214
PDB-101: Molecule of the Month: Chimeric Antigen Receptors
T cells may be engineered with chimeric antigen receptors to attack cancer cells.
molecule of the monthpdbantigenreceptors
https://pdb101.rcsb.org/motm/68
PDB-101: Molecule of the Month: Neurotrophins
Neurotrophins guide the development of the nervous system
molecule of the monthpdb
https://pdb101.rcsb.org/motm/200
PDB-101: Molecule of the Month: Quasisymmetry in Icosahedral Viruses
Viruses use quasisymmetry to build large capsids out of many small subunits
molecule of the monthpdbviruses
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https://pdb101.rcsb.org/motm/101
PDB-101: Molecule of the Month: Prions
Mad cow disease is caused by prion proteins that misfold and aggregate
molecule of the monthpdbprions