https://dash.harvard.edu/entities/publication/73120378-99c0-6bd4-e053-0100007fdf3b
Small-Molecule and Mutational Analysis of Allosteric Eg5 Inhibition by Monastrol
Background: A recent crystal structure of monastrol in a ternary complex with the kinesin Eg5 motor domain highlights a novel, induced-fit drug binding site at...
small moleculeanalysis
https://www.ncbi.nlm.nih.gov/Structure/pdb/1X88
1X88: Human Eg5 motor domain bound to Mg-ADP and monastrol
Kinesin-like protein KIF11ADENOSINE-5'-DIPHOSPHATEETHYL 4-(3-HYDROXYPHENYL)-6-METHYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLATEMAGNESIUM ION
humanmotordomain