Robuta

https://elifesciences.org/articles/10606/figures
A new method for developing biosensors from ligand binding domains that have concentration-dependent and selective responses to small molecules in yeast,...
in afiguresdatageneralstrategy
https://www.mdpi.com/1420-3049/29/5/1166
Breast cancer, characterized by its molecular intricacy, has witnessed a surge in targeted therapeutics owing to the rise of small-molecule drugs.
catalystshealingsymphonysynthesisclinical
https://www.ncbi.nlm.nih.gov/Structure/pdb/6XB7
RNA (41-MER)3-amino-N-(diaminomethylidene)-5-(dimethylamino)-6-(phenylethynyl)pyrazine-2-carboxamide
small moleculeirestargetingenterovirusreplication
https://nextgen-nano.co.uk/modifications-to-non-fullerene-small-molecule-acceptor-in-organic-thin-film-for-solar-cells-improve-efficiency/
small moleculemodificationsnonfullereneacceptor
https://www.rcsb.org/structure/3KGQ
Carboxypeptidase A liganded to an organic small-molecule: conformational changes
carboxypeptidase arcsbpdborganicsmall
https://newscenter.lbl.gov/2017/10/06/reimagining-hydrogen-small-molecule-large-scale-ideas/
Oct 11, 2017 - While hydrogen is often talked about as a pollution-free fuel of the future, especially for use in fuel cell electric vehicles, hydrogen can be used for much...
small moleculelarge scalereimagininghydrogenideas
https://www.ojp.gov/ncjrs/virtual-library/abstracts/innovative-engineering-and-sensing-strategies-aptamer-based-small
This study reviewed new approaches for the streamlined development of high-performance aptamer-based sensors for small-molecule detection.
small moleculeinnovativeengineeringsensingstrategies
https://www.rcsb.org/structure/8ITZ
Crystal structure of human Galectin-3 in complex with small molecule inhibitor
crystal structurercsbpdbhumangalectin
https://www.news-medical.net/news/20100303/AGN-209323-small-molecule-for-neuropathic-pain-Bristol-Myers-Squibb-Allergan-announce-global-agreement.aspx
Bristol-Myers Squibb Company and Allergan, Inc. today announced a global agreement for the development and commercialization of AGN-209323, a Phase II-ready,...
bristol myers squibbsmall moleculeneuropathic painagn
https://www.sgs.com/en-th/news/2025/01/decoding-the-differences-small-molecule-vs-microbiome-based-clinical-trials
Understand the unique considerations and challenges associated with the transition from non-clinical to clinical trials for microbiome-based therapeutics.
small moleculeclinical trialsdecodingdifferencesvs
https://www.patheon.com/us/en/our-capabilities/small-molecule.html
Turn to the CDMO you can trust for your small molecule drug development and manufacturing needs. Learn more about our fully integrated services.
small moleculedrug developmentampmanufacturingservices
https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2018.00058/full
P2X receptors are trimeric eukaryotic ATP-gated cation channels. Extracellular ATP - their physiological ligand - is released as a neurotransmitter and in co...
small moleculeligand bindingfrontiersmoleculardeterminants
https://www.ncbi.nlm.nih.gov/Structure/pdb/8A62
14-3-3 protein sigmaForkhead box protein...
small moleculestabilizercompound
https://www.prlog.org/13074336-global-small-molecule-api-market-to-reach-usd-286-03-billion-by-2030.html
Global Small Molecule API Market to Reach USD 286.03 Billion by 2030. The Global Small Molecule Active Pharmaceutical Ingredient (API) Market is witnessing...
small moleculeglobalapimarketreach
https://elifesciences.org/articles/52283/figures
G-quadruplex DNA regulates autophagy in neurons.
small moleculeg quadruplexfiguresdatastabilizers
https://www.sciencedaily.com/releases/2020/10/201002091031.htm
Scientists have found an ingredient that makes a vaccine more effective through an approach more often seen in materials science -- testing molecules that...
vaccine ingredientssmall moleculecouldhidinglibraries
https://www.rcsb.org/structure/6MXZ
Structure of 53BP1 Tudor domains in complex with small molecule UNC3474
rcsbpdbstructuretudordomains
https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2022.1023224/full?amp;utm_source=Email_to_authors_&utm_medium=Email&utm_content=T1_11.5e1_author&utm_campaign=Email_publication&field=&journalName=Frontiers_in_Medicine&id=1023224
Uveitis is a T cell-mediated, intraocular inflammatory disease and one of the main causes of blindness in industrialized countries. There is a high unmet nee...
a newsmall moleculefrontiersdhodhinhibitor
https://elifesciences.org/reviewed-preprints/93405/figures
small molecule drugspharmacologicallyinducingregenerativecardiac
https://elifesciences.org/reviewed-preprints/93405
small molecule drugspharmacologicallyinducingregenerativecardiac
https://pubmed.ncbi.nlm.nih.gov/20028853/
Activation of the beta-catenin and receptor kinase pathways occurs often in medulloblastoma, the most common pediatric malignant brain tumor. In this study, we...
small moleculeakt signalinginhibitorsphosphatidylinositolkinase
https://link.springer.com/article/10.1186/s12985-025-02867-8?error=cookies_not_supported&code=51d1633e-dac0-41f9-b309-a5a3c044906e
Jul 19, 2025 - Herpes simplex virus type 2 (HSV-2) is a highly prevalent human pathogen worldwide that not only causes genital herpes but is also associated with severe h
small moleculehsvinfectionviatargeting
https://elifesciences.org/articles/63402
Locally delivered small-molecule sclerostin inhibitors are able to promote local osteogenesis in vitro and in clinically relevant in vivo models by...
small moleculesclerostininhibitorspromoteosteogenesis
https://pharmafeatures.com/kinase-code-unveiled-mapping-the-molecular-determinants-of-adverse-events-in-small-molecule-inhibitor-therapies/
Oct 21, 2025 - Machine learning reveals how specific kinase inhibition patterns shape the safety profiles of targeted cancer therapies.
adverse eventskinasecodeunveiledmapping
https://www.rcsb.org/structure/3PWC
Bovine trypsin variant X(tripleGlu217Ile227) in complex with small molecule inhibitor
rcsbpdbbovinetrypsinvariant
https://elifesciences.org/articles/63284
Knockout of the methyltransferase ICMT prevents progerin methylation and improves survival in mice with Hutchinson-Gilford progeria syndrome (HGPS) and an ICMT...
small moleculeicmtinhibitordelayssenescence
https://www.technologynetworks.com/neuroscience/news/small-molecule-keeps-new-adult-neurons-straying-may-be-tied-schizophrenia-284390
Study shows the microRNA miR-19 helps budding adult brain cells stay on track.
small moleculenew adultkeepsneuronsstraying
https://www.ncbi.nlm.nih.gov/Structure/pdb/8ATP
14-3-3 protein sigmaEstrogen receptor2-chloranyl-~{N}-[[1-[4-[(4-chlorophenyl)amino]piperidin-4-yl]carbonylpiperidin-4-yl]methyl]ethanamideMAGNESIUM ION
small moleculestabilizer
https://pubmed.ncbi.nlm.nih.gov/26631113/
The transcription factor Myb plays a key role in the hematopoietic system and has been implicated in the development of leukemia and other human cancers....
acute myeloid leukemiasmall moleculetargetinginhibitor
https://www.bu.edu/bmerc/2013/06/24/computational-selection-of-small-molecule-inhibitors-of-the-eif4eeif4g-protein-protein-complex-involved-in-cancer/
small moleculecomputationalselectioninhibitors
https://www.ncbi.nlm.nih.gov/Structure/pdb/3U2O
Dihydroorotate dehydrogenase (quinone), mitochondrialACETATE IONFLAVIN MONONUCLEOTIDEOROTIC ACIDSULFATE IONmethyl...
dihydroorotate dehydrogenasecrystal structuredhodhcomplexsmall