https://openuserjs.org/scripts/Harest/Twitch_-_Mute_ads_and_optionally_hide_them
About | Twitch - Mute ads and optionally hide them | Userscripts | OpenUserJS
Automatically mutes the Twitch player when an advertisement started and unmute it once finished. You can also hide ads by setting disableDisplay to true.
mute adstwitchoptionallyhide