Robuta

https://cordis.europa.eu/project/id/101122595/de Targeting the undruggable: Leveraging neomorphic DNA-binding preferences of chimeric fusion... Many aggressive cancers, such as pediatric high-risk Ewing sarcoma and alveolar rhabdomyosarcoma, are fueled by and addicted to chimeric oncogenic... targetingleveraging https://keybase.io/neomorphic neomorphic (Jody Clements) | Keybase neomorphic (Jody Clements) is now on Keybase, an open source app for encryption and cryptography. jodyclementskeybase https://pubmed.ncbi.nlm.nih.gov/32683582/?dopt=Abstract Tumor-derived neomorphic mutations in ASXL1 impairs the BAP1-ASXL1-FOXK1/K2 transcription network Additional sex combs-like 1 (ASXL1) interacts with BRCA1-associated protein 1 (BAP1) deubiquitinase to oppose the polycomb repressive complex 1 (PRC1)-mediated... https://cordis.europa.eu/project/id/101122595/pl Targeting the undruggable: Leveraging neomorphic DNA-binding preferences of chimeric fusion... Many aggressive cancers, such as pediatric high-risk Ewing sarcoma and alveolar rhabdomyosarcoma, are fueled by and addicted to chimeric oncogenic... targetingleveraging