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https://www.leeds-live.co.uk/news/uk-world-news/nhs-methotrexate-warning-signs-mean-33162405 NHS Methotrexate warning signs that mean you should call 111 straight away - Leeds Live Methotrexate is usually the first medicine given for rheumatoid arthritis nhs methotrexate warningsigns https://www.chroniclelive.co.uk/news/uk-news/nhs-methotrexate-warning-signs-mean-33166551 NHS Methotrexate warning signs that mean you should call 111 straight away | Chronicle Live Jan 5, 2026 - Methotrexate is often the first medication prescribed for rheumatoid arthritis, but the NHS warns of serious side effects requiring urgent medical attention nhs methotrexate warningsigns