https://pubmed.ncbi.nlm.nih.gov/39964232/
Nmnat2 deficiency in the arcuate nucleus or paraventricular nucleus induces Sarm1-independent...
Nicotinamide mononucleotide adenylyltransferase 2 (Nmnat2) plays an important role in maintaining axon integrity, and the arcuate nucleus (ARC), and...
in thedeficiency
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.1000300
Endogenous Nmnat2 Is an Essential Survival Factor for Maintenance of Healthy Axons | PLOS Biology
We conclude that endogenous Nmnat2 prevents spontaneous degeneration of healthy axons and propose that, when present, the more long-lived, functionally related...