Robuta

https://www.ncbi.nlm.nih.gov/Structure/pdb/8FLK
Stimulator of interferon genes protein4-({[4-(2-tert-butyl-5,5-dimethyl-1,3-dioxan-2-yl)phenyl]methyl}amino)-3-methoxybenzoic acidcGAMP
cryo emstructurestingoligomerbound
https://pubmed.ncbi.nlm.nih.gov/18800165/
Recent in vitro and in vivo studies suggest that destabilized proteins with defective folding induce aggregation and toxicity in protein-misfolding diseases....
in a groupfolded proteinsamyloidoligomerconformation