https://www.surrey.ac.uk/research-projects/combining-oncolytic-viral-therapy-and-immune-checkpoint-blockadeto-achieve-optimal-prostate-cancer
Combining oncolytic viral therapy and immune checkpoint blockadeto achieve optimal prostate cancer...
oncolytic viral therapyimmune checkpoint
https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2025.1530583/full
Frontiers | Effect of bispecific recombinant oncolytic adenovirus carrying apoptin on apoptosis of...
ObjectiveIn this study, breast cancer cell line MCF-7 was infected with recombinant oncolytic adenovirus Ad-VT expressing apopsin protein, and its anti-tumou...
oncolytic adenovirusfrontierseffectrecombinant
https://www.hmpgloballearningnetwork.com/site/frmc/conference-coverage/measuring-pandemics-impact-oral-oncolytic-adherence
Measuring the Pandemic's Impact on Oral Oncolytic Adherence
Researchers at AMCP 2023 studied the number of prescription fills and therapy changes to determine how COVID-19 impacted adherence to oral oncolytic agents....
the pandemicmeasuringimpactoraloncolytic
https://pmc.ncbi.nlm.nih.gov/articles/PMC9365362/
Convection Enhanced Delivery of the Oncolytic Adenovirus Delta24-RGD in Patients with Recurrent...
Testing safety of Delta24-RGD (DNX-2401), an oncolytic adenovirus, locally delivered by convection enhanced delivery (CED) in tumor and surrounding brain of...
convection enhanced delivery
https://pmc.ncbi.nlm.nih.gov/articles/PMC3989763/
Oncolytic Immunotherapy: Dying the Right Way is a Key to Eliciting Potent Antitumor Immunity - PMC
Oncolytic viruses (OVs) are novel immunotherapeutic agents whose anticancer effects come from both oncolysis and elicited antitumor immunity. OVs induce mostly...
https://www.mdpi.com/1999-4915/9/12/382
Immunotherapeutic Potential of Oncolytic H-1 Parvovirus: Hints of Glioblastoma Microenvironment...
Glioblastoma, one of the most aggressive primary brain tumors, is characterized by highly immunosuppressive microenvironment. This contributes to glioblastoma...
h 1immunotherapeuticpotentialoncolyticparvovirus
https://www.frontiersin.org/journals/molecular-biosciences/articles/10.3389/fmolb.2024.1331369/full
Frontiers | Antimetastatic and antitumor activities of oncolytic NDV AMHA1 in a 3D culture model of...
Newcastle disease virus (NDV) AMHA1 is capable of killing cancer cells by direct replication or by induction of apoptosis alongside other pathways. Here, we ...
https://pmc.ncbi.nlm.nih.gov/articles/PMC8069290/
Oncolytic Virotherapy for Cancer: Clinical Experience - PMC
Oncolytic viruses are a new class of therapeutics which are largely in the experimental stage, with just one virus approved by the FDA thus far. While the...
oncolytic virotherapyclinical experiencecancerpmc
https://www.mdpi.com/books/reprint/5203-oncolytic-virus-immunotherapy
Oncolytic Virus Immunotherapy | MDPI Books
Dear Readers, Oncolytic Viruses (OV) are self-propagating agents that can selectively induce the lysis of cancer cells while sparing normal tissues....
oncolytic virusimmunotherapymdpibooks
https://www.dukehealth.org/clinical-trials/directory/pro00112883
PuMP: Oncolytic HSV1 MVR-C5252 in... | Clinical Trials at Duke
clinical trialspumponcolytichsv1mvr
https://www.marketresearch.com/Deep-Insights-Research-Co-DIR-v4285/Global-Oncolytic-Virus-Competitive-Landscape-37353786/
Global Oncolytic Virus Competitive Landscape Professional Research Report 2024
Global Oncolytic Virus Competitive Landscape Professional Research Report 2024 Global Oncolytic Virus Competitive Landscape Professional Research Report 2024...
oncolytic viruscompetitive landscapeprofessional researchglobalreport
https://pmc.ncbi.nlm.nih.gov/articles/PMC5432606/
Oncolytic Herpes Simplex Viral Therapy: A Stride toward Selective Targeting of Cancer Cells - PMC
Oncolytic viral therapy, which makes use of replication-competent lytic viruses, has emerged as a promising modality to treat malignancies. It has shown...
https://www.researchandmarkets.com/reports/6076065/oncolytic-adenovirus-market-report
Oncolytic Adenovirus Market Report 2026 - Research and Markets
The Oncolytic Adenovirus Market, valued at USD 143.57B in 2026, is projected to reach USD 195.85B by 2030, growing at a 8.1% CAGR.
oncolytic adenovirusmarket report2026 researchmarkets
https://bioimagingcore.be/q2a/tag/oncolytic
Recent questions tagged oncolytic - Bioimagingcore Q&A
recent questionstaggedoncolytic
https://www.mdpi.com/1999-4915/13/6/1082
Development of Group B Coxsackievirus as an Oncolytic Virus: Opportunities and Challenges
Oncolytic viruses have emerged as a promising strategy for cancer therapy due to their dual ability to selectively infect and lyse tumor cells and to induce...
group b
https://www.cancer.gov/news-events/cancer-currents-blog/2023/oncolytic-virus-blocking-tgf-beta
Oncolytic Virus Disrupts Immune-Blocking Protein - NCI
Researchers have modified an oncolytic virus so that it blocks the protein TGF-beta, helping expose tumors to the immune system.
oncolytic virusimmuneblockingproteinnci
https://pmc.ncbi.nlm.nih.gov/articles/PMC5758921/
Measles virus: Background and oncolytic virotherapy - PMC
Measles is a highly transmissible disease caused by measles virus and remains a major cause of child mortality in developing countries. Measles virus...
measles virusoncolytic virotherapybackgroundpmc
https://www.mdpi.com/2076-393X/12/9/958/notes
Vaccines | Free Full-Text | An Unconventional Case Study of Neoadjuvant Oncolytic Virotherapy for...
https://www.news-medical.net/news/20240806/Harnessing-oncolytic-viruses-for-cancer-immunotherapy-to-improve-treatment-outcomes.aspx
Harnessing oncolytic viruses for cancer immunotherapy to improve treatment outcomes
Aug 6, 2024 - Oncolytic virus (OV)-based immunotherapy has emerged as a promising strategy for cancer treatment, offering a unique potential to selectively target malignant...
oncolytic virusescancer immunotherapyharnessingimprovetreatment
https://pmc.ncbi.nlm.nih.gov/articles/PMC5779534/
Designing and building oncolytic viruses - PMC
Oncolytic viruses (OVs) are engineered and/or evolved to propagate selectively in cancerous tissues. They have a dual mechanism of action; direct killing of...
oncolytic virusesdesigningbuildingpmc
https://www.precedenceresearch.com/table-of-content/6939
Oncolytic Virus Therapy Market Size to Hit USD 11.13 Billion by 2034
The global oncolytic virus therapy market size is evaluated at USD 3.71 billion in 2025 and is predicted to hit around USD 11.13 billion by 2034, growing at a...
oncolytic virus therapy
https://pmc.ncbi.nlm.nih.gov/articles/PMC6025169/
Designer Oncolytic Adenovirus: Coming of Age - PMC
The licensing of talimogene laherparepvec (T-Vec) represented a landmark moment for oncolytic virotherapy, since it provided unequivocal evidence for the...
coming of ageoncolytic adenovirusdesignerpmc
https://finviz.com/news/71228/calidi-biotherapeutics-presents-systemic-oncolytic-platform-with-cd55-enhanced-expression-and-il-15-superagonist-payload-at-asco-annual-meeting
Calidi Biotherapeutics Presents systemic oncolytic platform with CD55-Enhanced expression and IL-15...
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https://informaconnect.com/tilt-arms-oncolytic-viruses-to-enable-t-cell-therapies/
Tilt arms oncolytic viruses to enable T-cell therapies
oncolytic virusestiltarmsenablecell
https://www.surrey.ac.uk/research-projects/engineering-oncolytic-hsv-optimal-spread-epithelial-ovarian-tumours
Engineering oncolytic HSV for optimal spread in epithelial ovarian tumours | University of Surrey
https://www.cancer.org/cancer/managing-cancer/treatment-types/immunotherapy/oncolytic-virus-therapy.html
Oncolytic Virus Therapy and Its Side Effects | American Cancer Society
Oncolytic virus therapy uses viruses that have been changed in a lab to destroy cancer cells. Learn more about how they work and their side effects.
oncolytic virus therapyside effectsamerican cancersociety
https://www.epo.org/fr/boards-of-appeal/decisions/t191203eu1
T 1203/19 (Oncolytic adenoviruses/INSTITUT CATALA D'ONCOLOGIA) du 26.04.2022
https://pmc.ncbi.nlm.nih.gov/articles/PMC9761050/
Repeated dosing improves oncolytic rhabdovirus therapy in mice via interactions with intravascular...
There is debate in the field of oncolytic virus (OV) therapy, whether a single viral dose, or multiple administrations, is better for tumor control. Using...
https://www.precedenceresearch.com/press-release/oncolytic-virus-based-gene-therapy-market
Rising Oncology Focus Drives Oncolytic Virus Gene Therapy Market
The Oncolytic Virus-Based Gene Therapy Market is expanding rapidly with increasing cancer prevalence, innovative trials, and breakthrough viral platforms.
oncology focusoncolytic virusgene therapyrisingdrives
https://pmc.ncbi.nlm.nih.gov/articles/PMC7352900/
Optimizing Oncolytic Viral Design to Enhance Antitumor Efficacy: Progress and Challenges - PMC
The field of oncolytic virotherapy has seen remarkable advancements in last two decades, leading to approval of the first oncolytic immuno-virotherapy,...
oncolytic viral
https://www.jpost.com/health-and-wellness/article-846255
Oncolytic viruses: The tiny warriors fighting brain cancer | The Jerusalem Post
Oncolytic viruses, once considered medical curiosities, are now cutting-edge tools in the fight against some of the most challenging cancers, like glioblastoma.
oncolytic virusesthe tinybrain cancerwarriorsfighting
https://pmc.ncbi.nlm.nih.gov/articles/PMC8987060/
Engineering strategies to enhance oncolytic viruses in cancer immunotherapy - PMC
Oncolytic viruses (OVs) are emerging as potentially useful platforms in treatment methods for patients with tumors. They preferentially target and kill tumor...
oncolytic virusescancer immunotherapyengineeringstrategiesenhance
https://www.biospace.com/press-releases/transgene-and-bioinvent-to-present-updated-data-on-armed-oncolytic-virus-bt-001-at-esmo-2025
Transgene and BioInvent to Present Updated Data on Armed Oncolytic virus BT-001 at ESMO 2025 -...
https://www.helsinki.fi/en/researchgroups/immunovirotherapy-lab/news/as-an-expert-in-oncolytic-virotherapy-professor-cerullo-is-ranked-no-13-in-the-world
As an expert in Oncolytic Virotherapy Professor Cerullo is ranked no: 13 in the world. |...
The founder of Expertscape believes that no one is an expert at anything unless they are investigating the leading edge of knowledge and are writing about it....
https://www.biospace.com/press-releases/calidi-biotherapeutics-presents-systemic-oncolytic-platform-with-cd55-enhanced-expression-and-il-15-superagonist-payload-at-asco-annual-meeting
Calidi Biotherapeutics Presents systemic oncolytic platform with CD55-Enhanced expression and IL-15...
https://pmc.ncbi.nlm.nih.gov/articles/PMC10213976/
Innovative retargeted oncolytic herpesvirus against nectin4-positive cancers - PMC
Nectin4 is a recently discovered tumor associated antigen expressed in cancers that constitute relevant unmet clinical needs, including the undruggable triple...
innovativeoncolyticherpesviruspositivecancers
https://www.dkfz.de/virotherapie/oncolytic-adenovirus-group
Oncolytic Adenovirus Group - Deutsches Krebsforschungszentrum
oncolytic adenovirusgroupdeutsches
https://www.biospace.com/synthetica-pioneering-closes-a-series-a-funding-round-to-support-development-of-oncolytic-bacterial-therapy-for-solid-tumors
Synthetica Pioneering Closes a Series A Funding Round to Support Development of Oncolytic Bacterial...
https://pmc.ncbi.nlm.nih.gov/articles/PMC5023393/
Phase 1 Study of Intravenous Oncolytic Poxvirus (vvDD) in Patients With Advanced Solid Cancers - PMC
We have conducted a phase 1 study of intravenous vvDD, a Western Reserve strain oncolytic vaccinia virus, on 11 patients with standard treatment-refractory...
https://pmc.ncbi.nlm.nih.gov/articles/PMC5630504/
Clinical Trials with Oncolytic Measles Virus: Current Status and Future Prospects - PMC
Attenuated Edmonston lineage measles virus (MV-Edm) vaccine strains can preferentially infect and lyse a wide variety of cancer cells. Oncolytic MV-Edm...
clinical trialsmeasles virus
https://pmc.ncbi.nlm.nih.gov/articles/PMC5472147/
Oncolytic Herpes Virus rRp450 Shows Efficacy in Orthotopic Xenograft Group 3/4 Medulloblastomas and...
Pediatric brain tumors including medulloblastoma and atypical teratoid/rhabdoid tumor are associated with significant mortality and treatment-associated...
oncolytic herpes virus
https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2024.1490414/full
Frontiers | Neutrophils in oncolytic virus immunotherapy
Oncolytic viruses have emerged as a highly promising modality for cancer treatment due to their ability to replicate specifically within tumors, carry therap...
oncolytic virusfrontiersneutrophilsimmunotherapy
https://bioimagingcore.be/q2a/204781/oncolytic-virus-therapy-with-ifn
Oncolytic Virus therapy with IFN - Bioimagingcore Q&A
Oncolytic Virus therapy with IFN from Creative Biolabs. Creative Biolabs provides customized, ... globally. Oncolytic Virus therapy with IFN
oncolytic virus therapyifnq
https://pmc.ncbi.nlm.nih.gov/articles/PMC3960873/
Oncolytic Newcastle Disease Virus as Cutting Edge between Tumor and Host - PMC
Oncolytic viruses (OVs) replicate selectively in tumor cells and exert anti-tumor cytotoxic activity. Among them, Newcastle Disease Virus (NDV), a bird RNA...
newcastle disease viruscutting edge
https://www.frontiersin.org/journals/cellular-neuroscience/articles/10.3389/fncel.2022.819363/full
Frontiers | Glioblastoma microenvironment and its reprogramming by oncolytic virotherapy
Glioblastoma (GBM), a highly aggressive form of brain tumor, responds poorly to current conventional therapies, including surgery, radiation therapy, and sys...
frontiersglioblastomamicroenvironmentreprogrammingoncolytic
https://pmc.ncbi.nlm.nih.gov/articles/PMC12730407/
Oncolytic Viruses in Glioblastoma: Clinical Progress, Mechanistic Insights, and Future Therapeutic...
Glioblastoma (GBM) is the most aggressive primary brain tumor, with limited treatment options and a poor median survival of around 15 months. Oncolytic viruses...
oncolytic virusesglioblastomaclinical
https://www.spandidos-publications.com/10.3892/ol.2021.13061
[Retracted] Oncolytic virotherapy with human telomerase reverse transcriptase promoter regulation...
Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.
oncolytic virotherapyreverse transcriptaseretractedhumantelomerase
https://www.wikidata.org/wiki/Q45717443
Present status of oncolytic virus studies - Wikidata
scientific article published in June 1960
oncolytic viruspresentstatusstudieswikidata
https://pmc.ncbi.nlm.nih.gov/articles/PMC7316762/
Advances and potential pitfalls of oncolytic viruses expressing immunomodulatory transgene therapy...
Glioblastoma (GBM) is an immunosuppressive, lethal brain tumor. Despite advances in molecular understanding and therapies, the clinical benefits have remained...
oncolytic virusesadvancespotentialpitfalls
https://www.mdpi.com/2072-6694/13/3/544
Measles Virus as an Oncolytic Immunotherapy
Measles virus (MeV) preferentially replicates in malignant cells, leading to tumor lysis and priming of antitumor immunity. Live attenuated MeV vaccine strains...
measles virusoncolyticimmunotherapy
https://www.mdpi.com/1999-4915/15/2/363
Establishing a New Platform to Investigate the Efficacy of Oncolytic Virotherapy in a Human Ex Vivo...
Oncolytic virotherapy constitutes a promising treatment option for many solid cancers, including peritoneal carcinomatosis (PC), which still represents a...
https://www.broadinstitute.org/publications/broad1371471
Retargeted oncolytic viruses engineered to remodel the tumor microenvironment for glioblastoma...
oncolytic virusesthe tumorengineered
https://pmc.ncbi.nlm.nih.gov/articles/PMC8284840/
Oncolytic HSV-1 G207 Immunovirotherapy for Pediatric High-Grade Gliomas - PMC
Outcomes in children and adolescents with recurrent or progressive high-grade glioma are poor, with a historical median overall survival of 5.6 months....
hsv 1high gradeoncolyticg207
https://pmc.ncbi.nlm.nih.gov/articles/PMC8043042/
Intratumoral OH2, an oncolytic herpes simplex virus 2, in patients with advanced solid tumors: a...
OH2 is a genetically engineered oncolytic herpes simplex virus type 2 designed to selectively amplify in tumor cells and express granulocyte-macrophage...
herpes simplex virus 2
https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2022.839536/full
Frontiers | Senecavirus A as an Oncolytic Virus: Prospects, Challenges and Development Directions
Oncolytic viruses have the capacity to selectively kill infected tumor cells and trigger protective immunity. As such, oncolytic virotherapy has become a pro...
senecavirus a
https://www.fiercebiotech.com/biotech/merck-inks-394m-takeover-oncolytic-virus-play-viralytics
Merck inks $394M takeover of oncolytic virus play Viralytics | Fierce Biotech
Feb 21, 2018 - Merck is set to pay $394 million to acquire Viralyti
oncolytic virusmerckinkstakeover
https://www.broadinstitute.org/publications/broad1374011
Persistent T cell activation and cytotoxicity against glioblastoma following single oncolytic virus...
t cell activation
https://pmc.ncbi.nlm.nih.gov/articles/PMC5086626/
Measles to the Rescue: A Review of Oncolytic Measles Virus - PMC
Oncolytic virotherapeutic agents are likely to become serious contenders in cancer treatment. The vaccine strain of measles virus is an agent with an...
to the rescuea reviewoncolytic virusmeaslespmc
https://www.mdpi.com/1999-4915/13/6/1019
Human Retrotransposons and the Global Shutdown of Homeostatic Innate Immunity by Oncolytic...
Although the oncolytic parvovirus H-1PV has entered clinical trials, predicting therapeutic success remains challenging. We investigated whether the antiviral...
https://www.lytixbiopharma.com/
Lytix Biopharma | Oncolytic Immunotherapy
Lytix Biopharma is developing first-in-class oncolytic molecule therapies that kill cancer with direct and abscopal tumor effects. Redefining the standard of...
lytixbiopharmaoncolyticimmunotherapy
https://www.biospace.com/oncomyx-announces-presentation-of-preclinical-efficacy-data-of-novel-oncolytic-immunotherapy-at-sitc-2020
OncoMyx Announces Presentation of Preclinical Efficacy Data of Novel Oncolytic Immunotherapy at...
Nov 9, 2020 - OncoMyx Therapeutics, a privately-held oncolytic immunotherapy company, announced the presentation of preclinical data at the Society for Immunotherapy of...
oncolytic immunotherapyannouncespresentationpreclinical
https://pmc.ncbi.nlm.nih.gov/articles/PMC6911943/
Oncolytic Viruses for Cancer Therapy: Barriers and Recent Advances - PMC
Oncolytic viruses (OVs) are powerful new therapeutic agents in cancer therapy. With the first OV (talimogene laherparepvec [T-vec]) obtaining US Food and Drug...
oncolytic virusescancer therapybarriersrecentadvances
https://www.gminsights.com/industry-analysis/oncolytic-virotherapy-market
Oncolytic Virotherapy Market Size & Share Report, 2032
The oncolytic virotherapy market size was valued at USD 20.1 million in 2023 and is anticipated to showcase growth at 26.9% CAGR from 2024 and 2032 driven by...
oncolytic virotherapymarket sizesharereport2032
https://pmc.ncbi.nlm.nih.gov/articles/PMC7352817/
Efficacy and Safety of Oncolytic Viruses in Randomized Controlled Trials: A Systematic Review and...
Oncolytic virotherapy is a promising antitumor therapeutic strategy. It is based on the ability of viruses to selectively kill cancer cells and induce host...
efficacy and safetyrandomized controlled trials