https://elifesciences.org/reviewed-preprints/92889
Senescence of endplate osteoclasts induces sensory innervation and spinal pain
sensory innervationsenescenceendplateosteoclastsinduces
https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2017.00954/full
Frontiers | Emerging Roles of Osteoclasts in the Modulation of Bone Microenvironment and Immune...
Multiple myeloma (MM) is the one of most common form of hematologic malignancy resulting from cancerous proliferation of mature malignant plasma cells (MPCs)...
emerging roles
https://www.mdpi.com/2072-6643/14/22/4869
Lacticaseibacillus rhamnosus MG4706 Suppresses Periodontitis in Osteoclasts, Inflammation-Inducing...
Periodontitis is a chronic inflammatory disease characterized by tooth loss due to inflammation and the loss of alveolar bone. Periodontitis is closely related...
lacticaseibacillus rhamnosusperiodontitisosteoclastsinflammation
https://elifesciences.org/reviewed-preprints/98665/figures
Formation of Multinucleated Osteoclasts Depends on an Oxidized Species of Cell Surface Associated...
https://elifesciences.org/articles/54493
Dissecting the phenotypic and functional heterogeneity of mouse inflammatory osteoclasts by the...
Osteoclasts emerging in inflammation are heterogeneous and encompass a strongly inflammatory subset with a high resorbing activity and an immune suppressive...
dissectingphenotypicfunctional
https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2023.1110369/full
Frontiers | ECSIT is essential for RANKL-induced stimulation of mitochondria in osteoclasts and a...
Estrogens inhibit bone resorption and preserve bone mass, at least in part, via direct effects on osteoclasts. The binding of RANKL, the critical cytokine fo...
https://elifesciences.org/articles/75610v1
Nanoscale architecture and coordination of actin cores within the sealing zone of human osteoclasts...
https://www.news-medical.net/life-sciences/What-are-Osteoclasts.aspx
What are Osteoclasts?
Nov 27, 2019 - Osteoclasts are specialized, multinucleated cells that play a vital role in bone development and regeneration.
osteoclasts
https://elifesciences.org/articles/75610v2
Nanoscale architecture and coordination of actin cores within the sealing zone of human osteoclasts...
https://www.jci.org/articles/view/121561/pdf
JCI - Subchondral bone osteoclasts induce sensory innervation and osteoarthritis pain
subchondral bonesensory innervationjciosteoclastsinduce
https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2019.00684/full
Frontiers | mTORC1 Activation in Osteoclasts Prevents Bone Loss in a Mouse Model of Osteoporosis
The mechanistic/mammalian target of rapamycin (mTOR) is widely implicated in the pathogenesis of various diseases, including cancer, obesity, and cardiovascu...
https://pmc.ncbi.nlm.nih.gov/articles/PMC3366812/
Siglec-15 Protein Regulates Formation of Functional Osteoclasts in Concert with DNAX-activating...
Background: ITAM-harboring DAP12 contributes to functional osteoclast formation. Results: Siglec-15 is NFAT2-inducible and functions with DAP12 to promote...
https://www.jci.org/articles/view/121561/ga
JCI - Subchondral bone osteoclasts induce sensory innervation and osteoarthritis pain
subchondral bonesensory innervationjciosteoclastsinduce
https://pmc.ncbi.nlm.nih.gov/articles/PMC394349/
Human primary osteoclasts: in vitro generation and applications as pharmacological and clinical...
Osteoclasts are cells of hematopoietic origin with a unique property of dissolving bone; their inhibition is a principle for treatment of diseases of bone...
in vitrohumanprimaryosteoclasts