https://www.gov.uk/drug-safety-update/tapentadol-palexia-risk-of-seizures-and-reports-of-serotonin-syndrome-when-co-administered-with-other-medicines?UNLID=803528536202429105635&UNLID=1016570046202475112352&UNLID=305511363202641825256
Tapentadol (Palexia): risk of seizures and reports of serotonin syndrome when co-administered with...
Tapentadol may increase seizure risk in patients taking other medicines that lower seizure threshold, for example, antidepressants and antipsychotics....