https://nmr.oxinst.com/learning/learning/view/article/pich-overwinds-dna-to-help-it-untangle
PICH-directed positive supercoiling promotes DNA disentanglement — Oxford Instruments Learning...
May 29, 2026 - Molecular-level images of DNA structure showed that positive supercoiling induced by the enzyme PICH actually aided subsequent disentanglement.
positive supercoilingoxford instrumentspichdirectedpromotes
https://abberior.rocks/expertise/publications/star-is-a-positive-regulator-of-topoisomerase-i-activity-involved-in-supercoiling-maintenance-in-streptococcus-pneumoniae/
StaR Is a Positive Regulator of Topoisomerase I Activity Involved in Supercoiling Maintenance in...
The DNA topoisomerases gyrase and topoisomerase I as well as the nucleoid-associated protein HU maintain supercoiling levels in Streptococcus pneumoniae, a...
is astarpositiveregulatortopoisomerase