https://elifesciences.org/articles/94720
Why does protein kinase A respond to purine nucleosides in certain pathogens, but not to the cyclic nucleotides that activate this kinase in most other...
protein kinase aprobingligandselectivitypathogens
https://elifesciences.org/articles/60715v2/peer-reviews
Ligands with different efficacy profiles shift the free energy landscape of the beta2 adrenergic receptor activation and stabilize diverse active-like states...
peer reviewg proteinidentificationligandspecific
https://www.ncbi.nlm.nih.gov/Structure/pdb/6QBA
DNA-binding protein 7aRetinol-binding protein 42-[({4-[2-(trifluoromethyl)phenyl]piperidin-1-yl}carbonyl)amino]benzoic acidACETATE...
retinol binding proteincrystal structure
https://pubmed.ncbi.nlm.nih.gov/34302750/
G-protein-coupled receptors (GPCRs) represent the largest family of drug targets. Upon activation, GPCRs signal primarily via a diverse set of heterotrimeric G...
g protein signalingliganddirectedbiasdopamine
https://pubmed.ncbi.nlm.nih.gov/31870540/
Fatty acid binding proteins play an important role in the transportation of fatty acids. Despite intensive studies, how fatty acids enter the protein cavity...
fatty acidbinding proteinligandentryvia