resistance evolution - Robuta Search

https://pmc.ncbi.nlm.nih.gov/articles/PMC12209985/ Streptococcus suis: Epidemiology and resistance evolution of an emerging zoonotic bacteria - PMC The health of humans and the growth of the agriculture industry are seriously threatened by the emerging zoonotic pathogen Streptococcus suis (S. suis). In the... streptococcus suis resistance evolution https://elifesciences.org/articles/64116 Multi-step vs. single-step resistance evolution under different drugs, pharmacokinetics, and... The number and effects of mutations leading to full drug resistance crucially determine treatment failure probability and should be used to inform... resistance evolution different drugs multi step vs https://pubmed.ncbi.nlm.nih.gov/41987223/ Convergent evolution of complex structural variants drives therapy resistance in metastatic... We conclude that cSVs, particularly ecDNA, are a pervasive contributor to intra-patient heterogeneity in late-stage mCRPC and a key driver of targeted therapy... convergent evolution structural variants complex https://pmc.ncbi.nlm.nih.gov/articles/PMC21672/ Drug concentration heterogeneity facilitates the evolution of drug resistance - PMC Pathogenic microorganisms use Darwinian processes to circumvent attempts at their control through chemotherapy. In the case of HIV-1 infection, in which drug... the evolution drug concentration heterogeneity resistance https://elifesciences.org/reviewed-preprints/95058/reviews Fast Evolution of SOS-Independent Multi-Drug Resistance in Bacteria multi drug resistance fast evolution sos independent https://elifesciences.org/articles/78834 Pre-existing chromosomal polymorphisms in pathogenic E. coli potentiate the evolution of resistance... Interactions between a mobile resistance gene and chromosomal mutations drive the evolution of high-level antibiotic resistance. pathogenic e coli https://pmc.ncbi.nlm.nih.gov/articles/PMC12334625/ Exploiting collateral sensitivity in the evolution of resistance to tyrosine kinase inhibitors in... Broad-spectrum multi-target tyrosine kinase inhibitors (mTKIs) are clinically approved for the treatment of soft tissue sarcomas (STS). However, acquired... in the https://elifesciences.org/reviewed-preprints/95058 Fast Evolution of SOS-Independent Multi-Drug Resistance in Bacteria multi drug resistance fast evolution sos independent https://www.gu.se/en/research/the-role-of-the-environment-in-the-selection-and-evolution-of-antibiotic-resistance The role of the environment in the selection and evolution of antibiotic resistance | University of... This project combines classical bacterial culturing, metagenomic DNA sequencing, bioinformatics analyses, advanced molecular biology, X-ray crystallography and... the role antibiotic resistance environment https://scienceblogs.com/insolence/2007/05/24/medicine-and-evolution-part-11-studying Medicine and Evolution, Part 11: Studying the mechanism of multidrug resistance | ScienceBlogs Our creationist neurosurgeon, Dr. Michael Egnor, isn't going to like this one bit. No doubt he'll try to call it "artificial selection" or a "tautology" when... part 11 https://studylib.net/doc/27664894/variation-and-selection-qp Genetics & Evolution Exam Paper: Alleles, Resistance, Finches Explore genetics and evolution with this exam paper covering allele frequencies, sickle cell anemia, antibiotic resistance, blood groups, and Galapagos finches. exam paper genetics evolution alleles resistance https://elifesciences.org/articles/01322 Evolution of extreme resistance to ionizing radiation via genetic adaptation of DNA repair | eLife Experiments on E. coli show that multiple mechanisms contribute to extreme resistance to ionizing radiation in bacteria, with mutations to three genes for DNA... https://www.gov.uk/research-for-development-outputs/differences-in-the-dynamics-of-viral-rebound-and-evolution-of-resistance-between-cbv-nvp-and-cbv-abc-nora-sub-study-of-dart-trial-uncovered-in-the-absence-of-viral-load-monitoring-in-real-time Differences in the dynamics of viral rebound and evolution of resistance between CBV/NVP and... https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2017.01217/full Frontiers | Host Resistance and Temperature-Dependent Evolution of Aggressiveness in the Plant... Understanding how habitat heterogeneity may affect the evolution of plant pathogens is essential to effectively predict new epidemiological landscapes and ma... host resistance https://www.stir.ac.uk/research/hub/publication/1862875 Book Chapter | Evolution of sea louse (Copepoda: Caligidae) resistance against control agents |... book chapter sea louse https://www.gov.uk/research-for-development-outputs/emergence-and-evolution-of-drug-resistance-in-the-absence-of-viral-load-monitoring-during-48-weeks-of-combivir-tenofovir-within-the-dart-trial Emergence and evolution of drug resistance in the absence of viral load monitoring during 48 weeks... https://www.progress-net.de/ Pneumonia Research Network on Genetic Resistance and Susceptibility for the Evolution of Severe... https://pmc.ncbi.nlm.nih.gov/articles/PMC7850051/ Selective Sweeps in a Nutshell: The Genomic Footprint of Rapid Insecticide Resistance Evolution in... Among the most familiar forms of human-driven evolution on ecological time scales is the rapid acquisition of resistance to pesticides by insects. Since the... in a nutshell https://www.osti.gov/pages/biblio/1832660-structural-evolution-dna-repair-self-resistance-mechanism-targeting-genotoxic-secondary-metabolites Structural evolution of a DNA repair self-resistance mechanism targeting genotoxic secondary... The U.S. Department of Energy's Office of Scientific and Technical Information a dna https://www.psu.edu/news/research/story/what-dose-medication-best-prevent-evolution-drug-resistance What dose of medication is best to prevent the evolution of drug resistance? | Penn State University A new model shows that the standard practice of treating infections with the highest tolerable dose of anti-microbe medications may not be best for preventing... https://www.osti.gov/biblio/2342003 Lithium Loss, Resistance Growth, Electrode Expansion, Gas Evolution, and Li Plating: Analyzing... Analysis of the performance evolution and failure mechanisms of commercial Li-ion batteries is crucial for improving testing methods, accurately modeling... https://pmc.ncbi.nlm.nih.gov/articles/PMC4209135/ Parallel Evolution of Tetrodotoxin Resistance in Three Voltage-Gated Sodium Channel Genes in the... Members of a gene family expressed in a single species often experience common selection pressures. Consequently, the molecular basis of complex adaptations... voltage gated sodium channel https://elifesciences.org/articles/20420/peer-reviews Peer review in Ribosomal mutations promote the evolution of antibiotic resistance in a multidrug... Mutations in several components of a bacterial ribosome are shown to broadly decrease antibiotic and stress sensitivity, and readily accessible reversion... https://www.mdpi.com/2077-0383/12/6/2414 Evolution of Antibiotic Resistance in Escherichia coli and Klebsiella pneumoniae Clinical Isolates... In recent years, we have witnessed a growing drug resistance among bacteria, which is associated with the use and availability of an increasing number of... antibiotic resistance escherichia coli https://www.sri.com/publication/biosciences-health-pubs/an-early-21st-century-perspective-on-antibiotic-resistance-evolution-global-response-and-possible-solutions/ An Early 21st Century Perspective on Antibiotic Resistance Evolution, Global Response, and Possible... early 21st century https://sheffield.ac.uk/biosciences/news/scientists-identify-factors-which-drive-evolution-herbicide-resistance Scientists identify factors which drive the evolution of herbicide resistance | Biosciences | The... New findings could have an important impact on medicine as well as agriculture. scientists identify the evolution herbicide resistance factors drive https://www.frontiersin.org/research-topics/70110/generative-ai-and-large-language-models-in-microbial-evolution-resistance-mechanisms-and-antimicrobial-drug-discovery/impact Frontiers | Generative AI and Large Language Models in Microbial Evolution, Resistance Mechanisms,... Generative AI and Large Language Models (LLMs) are transforming microbiology by providing novel insights into microbial evolution, resistance mechanisms, and... large language models generative ai