Robuta

https://www.ncbi.nlm.nih.gov/Structure/pdb/4X0F 4X0F: Crystal structure of crosslink stabilized long-form PDE4B in complex with (R)-(-)-rolipram cAMP-specific 3',5'-cyclic phosphodiesterase 4BIODIDE IONMAGNESIUM IONROLIPRAMZINC ION https://pmc.ncbi.nlm.nih.gov/articles/PMC24568/ Rolipram, a type IV-specific phosphodiesterase inhibitor, facilitates the establishment of... In an attempt to improve behavioral memory, we devised a strategy to amplify the signal-to-noise ratio of the cAMP pathway, which plays a central role in... a typephosphodiesterase inhibitorthe establishmentrolipramiv