Robuta

https://pubmed.ncbi.nlm.nih.gov/37805627/ Super-enhancer hijacking drives ectopic expression of hedgehog pathway ligands in meningiomas Hedgehog signaling mediates embryologic development of the central nervous system and other tissues and is frequently hijacked by neoplasia to facilitate... super enhancer https://pubmed.ncbi.nlm.nih.gov/36877164/ LSD1 Inhibition Disrupts Super-Enhancer-Driven Oncogenic Transcriptional Programs in... LSD1 drives prostate cancer progression by activating super-enhancer-mediated oncogenic programs, which can be targeted with the combination of LSD1 and BRD4... super enhancer inhibition disrupts driven programs https://scholars.duke.edu/publication/1521494 Scholars@Duke publication: Super-enhancer signature reveals key mechanisms associated with... super enhancer scholars duke publication https://pubmed.ncbi.nlm.nih.gov/26560027/ Genetic predisposition to neuroblastoma mediated by a LMO1 super-enhancer polymorphism Neuroblastoma is a paediatric malignancy that typically arises in early childhood, and is derived from the developing sympathetic nervous system. Clinical... genetic predisposition by a super enhancer neuroblastoma mediated https://sciencedaily.com/releases/2022/01/220111091350.htm Modular super-enhancer controls retinal development | ScienceDaily Scientists have identified distinct functions for regions of a super-enhancer that controls gene expression during retina formation, calling it a 'modular'... super enhancer modular controls retinal development https://pubmed.ncbi.nlm.nih.gov/38836550/ Super-enhancer-driven ameboidal-type cell migration-related MMP14 expression in tongue squamous... SEs and related key motifs transcriptional regulate tumor metastasis-associated MMP14 and might be potential therapeutic targets for TSCC. https://pure.psu.edu/en/publications/is-a-super-enhancer-greater-than-the-sum-of-its-parts/ Is a super-enhancer greater than the sum of its parts? - Penn State https://www.cirm.ca.gov/about-cirm/publications/cd47-associated-super-enhancer-links-pro-inflammatory-signalling-cd47-upregulation-breast-cancer/ A CD47-associated super-enhancer links pro-inflammatory signalling to CD47 upregulation in breast...