targeting stem - Robuta Search

https://scholars.duke.edu/publication/954292 Scholars@Duke publication: Targeting stem cell behavior in desmoid tumors (aggressive fibromatosis)... targeting stem cell behavior https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2016.00533/full Frontiers | Exosome-Based Cancer Therapy: Implication for Targeting Cancer Stem Cells Drug resistance, difficulty in specific targeting and self-renewal properties of cancer stem cells (CSCs) all contribute to cancer treatment failure and rela... cancer therapy targeting stem frontiers exosome based https://cordis.europa.eu/project/id/682935 Pleiotropic treatment of cancer: RANK inhibitors targeting cancer stem cells and immunity |... "Thousands of cancer patients worldwide are taking RANKL inhibitors for the management of bone metastasis, based on the key role of RANKL and its receptor,... targeting stem treatment cancer rank https://pubmed.ncbi.nlm.nih.gov/26700806/ Targeting PTPRK-RSPO3 colon tumours promotes differentiation and loss of stem-cell function Colorectal cancer remains a major unmet medical need, prompting large-scale genomics efforts in the field to identify molecular drivers for which targeted... https://www.wikidata.org/wiki/Q72583957 Simple screening procedure to detect gene targeting events in embryonic stem cells - Wikidata scientific article published on 01 January 1993 https://www.sciencedaily.com/releases/2010/01/100131145507.htm Targeting cancer stem cells in the lab | ScienceDaily Understanding of the particular cancer cells within a tumour that drive its growth could now advance more rapidly, thanks to new research. Scientisist now show... cancer stem cells in the lab targeting sciencedaily https://microbiology.weill.cornell.edu/targeting-autocrine-regulatory-loop-cancer-stem-cells-impairs-progression-and-chemotherapy Targeting an Autocrine Regulatory Loop in Cancer Stem-like Cells Impairs the Progression and... https://www.mdpi.com/2077-0383/10/24/5805 Shedding Light on Targeting Chronic Myeloid Leukemia Stem Cells Chronic myeloid leukemia stem cells (CML LSCs) are a rare and quiescent population that are resistant to tyrosine kinase inhibitors (TKI). When TKI therapy is... chronic myeloid leukemia shedding light targeting stem cells https://pubmed.ncbi.nlm.nih.gov/40239632/?dopt=Abstract Catalytic neural stem cell exosomes for multi-stage targeting and synergistical therapy of retinal... Neuronal damage of the retina is a leading cause of visual impairment in patients with retinal ischemia-reperfusion injury (RIRI). Building on our clinical and... https://www.mdpi.com/1422-0067/22/23/13044 Natural Products Targeting Cancer Stem Cells for Augmenting Cancer Therapeutics Cancer stem cells (CSC) have been identified in several types of solid tumors. In some cases, CSC may be the source of all the tumor cells, the cause of the... cancer stem cells natural products targeting augmenting therapeutics https://www.frontiersin.org/journals/cell-and-developmental-biology/articles/10.3389/fcell.2019.00016/full Frontiers | Meeting the Challenge of Targeting Cancer Stem Cells Notwithstanding cancer patients benefit from a plethora of therapeutic alternatives, drug resistance remains a critical hurdle. Indeed, the high mortality ra... the challenge frontiers meeting targeting cancer https://pubmed.ncbi.nlm.nih.gov/39166412/ Targeting Bacteria-Induced Ferroptosis of Bone Marrow Mesenchymal Stem Cells to Promote the Repair... The specific mechanisms underlying bacteria-triggered cell death and osteogenic dysfunction in host bone marrow mesenchymal stem cells (BMSCs) remain unclear,... https://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0002870 Targeting Echinococcus multilocularis Stem Cells by Inhibition of the Polo-Like Kinase EmPlk1 |... Author Summary The lethal disease AE is characterized by continuous and infiltrative growth of the metacestode larva of the tapeworm E. multilocularis within... https://www.cirm.ca.gov/our-progress/awards/directed-evolution-novel-aav-variants-enhanced-gene-targeting-pluripotent-human-stem-cells-and-investigation-dopaminergic-neuron-differentiation/ Directed Evolution of Novel AAV Variants for Enhanced Gene Targeting in Pluripotent Human Stem... https://www.cirm.ca.gov/about-cirm/newsroom/press-releases/10182018-stem-cell-agency-invests-new-immunotherapy-approach-hiv/ Stem Cell Agency Invests in New Immunotherapy Approach to HIV, Plus Promising Projects Targeting... https://iscrm.uw.edu/recent_research/targeting-nad-metabolism-as-interventions-for-mitochondrial-disease/ Targeting NAD+ Metabolism as Interventions for Mitochondrial Disease - Institute for Stem Cell &... Aug 1, 2019 - Scientific Reports, February 2019 mitochondrial disease targeting nad metabolism interventions https://www.ophth.wisc.edu/blog/2017/05/01/resveratrol-targeting-of-akt-and-p53-in-glioblastoma-and-glioblastoma-stem-like-cells-to-suppress-growth-and-infiltration/ Resveratrol targeting of AKT and p53 in glioblastoma and glioblastoma stem-like cells to suppress... PubMed ID: 27419830 Author(s): Clark PA, Bhattacharya S, Elmayan A, Darjatmoko SR, Thuro BA, Yan MB, van Ginkel PR, Polans AS, Kuo JS. Resveratrol targeting of... https://pure.psu.edu/en/publications/targeting-stem-cell-derived-tissue-associated-regulatory-t-cells-/ Targeting Stem Cell-Derived Tissue-Associated Regulatory T Cells for Type 1 Diabetes Immunotherapy... https://pubmed.ncbi.nlm.nih.gov/32296030/ Targeting cancer stem cell pathways for cancer therapy Since cancer stem cells (CSCs) were first identified in leukemia in 1994, they have been considered promising therapeutic targets for cancer therapy. These... cancer stem cell targeting pathways therapy https://pubmed.ncbi.nlm.nih.gov/2822260/?dopt=Abstract&holding=f1000,f1000m,isrctn Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells We mutated, by gene targeting, the endogenous hypoxanthine phosphoribosyl transferase (HPRT) gene in mouse embryo-derived stem (ES) cells. A specialized... site directed mutagenesis https://pubmed.ncbi.nlm.nih.gov/41326331/ Targeting leukemic stem cell biomechanics suppresses stemness and enhances NK cell-mediated... Acute myeloid leukemia (AML) is primarily driven by leukemic stem cells (LSCs), the main cause of relapse and therapy resistance. Here, we discover that LSCs... stem cell targeting biomechanics https://pubmed.ncbi.nlm.nih.gov/22655230/ Therapeutic targeting of cancer stem cells Recent breakthroughs in translational oncology are opening new perspectives for the treatment of cancer. The advent of targeted therapies has provided the... therapeutic targeting cancer stem cells https://pubmed.ncbi.nlm.nih.gov/33582212/ Targeting cancer stem cells by disulfiram and copper sensitizes radioresistant chondrosarcoma to... Overcoming the radiosensitivity of chondrosarcoma (CS), the second most common primary bone tumor, is needed. Radioresistance is attributed to cancer stem... cancer stem cells https://mrm.research.mcgill.ca/2021/07/mrm-insights-targeting-oxphos-in-glioma-stem-cells/ MRM Insights: Targeting OXPHOS in Glioma Stem Cells | MRM Jul 14, 2021 - Every month, a member of the MRM Network is writing about stem cells and regenerative medicine from a different perspective. mrm insights targeting oxphos glioma https://digital.library.adelaide.edu.au/items/46de60d5-17bf-4227-ab60-3617e99ef3a5 In silico modelling of a cancer stem cell-targeting agent and its effects on tumour control during... Head and neck cancers (HNC), like most solid tumours, contain a subpopulation of cancer stem cells (CSC) that are commonly responsible for treatment failure....