withaferin - Robuta Search

https://pmc.ncbi.nlm.nih.gov/articles/PMC4924683/ Withaferin-A suppress AKT induced tumor growth in colorectal cancer cells - PMC The oncogenic activation of AKT gene has emerged as a key determinant of the aggressiveness of colorectal cancer (CRC); hence, research has focused on... withaferin a https://pmc.ncbi.nlm.nih.gov/articles/PMC9966696/ Withaferin A: A Pleiotropic Anticancer Agent from the Indian Medicinal Plant Withania somnifera... Cancer represents the second most deadly disease and one of the most important public health concerns worldwide. Surgery, chemotherapy, radiation therapy, and... withaferin a anticancer agent from the https://pmc.ncbi.nlm.nih.gov/articles/PMC10519218/ Withaferin A: A Dietary Supplement with Promising Potential as an Anti-Tumor Therapeutic for Cancer... Cancer, as the leading cause of death worldwide, poses a serious threat to human health, making the development of effective tumor treatments a significant... https://pmc.ncbi.nlm.nih.gov/articles/PMC7878893/ Withaferin A alleviates fulminant hepatitis by targeting macrophage and NLRP3 - PMC Fulminant hepatitis (FH) is an incurable clinical syndrome where novel therapeutics are warranted. Withaferin A (WA), isolated from herb Withania Somnifera, is... withaferin a fulminant hepatitis https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2025.1540237/full Frontiers | Fortified Withaferin A accelerates the transition from fibrovascular to bone remodeling... IntroductionThis study shows that Fortified Withaferin A (FWA, 10% w/w) accelerates bone healing, advancing from the fibrovascular to bone remodeling stage w... withaferin a the transition https://pmc.ncbi.nlm.nih.gov/articles/PMC6862083/ Withania Somnifera (Ashwagandha) and Withaferin A: Potential in Integrative Oncology - PMC Ashwagandha (Withania Somnifera, WS), belonging to the family Solanaceae, is an Ayurvedic herb known worldwide for its numerous beneficial health activities... withania somnifera integrative oncology ashwagandha withaferin https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2018.00248/full Frontiers | An Adaptogen: Withaferin A Ameliorates in Vitro and in Vivo Pulmonary Fibrosis by... Pulmonary fibrosis is chronic lung disease with only two FDA approved clinically available drugs, with limited safety profile. Inadequate therapy motivated u... https://pmc.ncbi.nlm.nih.gov/articles/PMC6200817/ Withaferin A inhibits Epithelial to Mesenchymal Transition in Non-Small Cell Lung Cancer Cells - PMC Lung cancer is the leading cause of cancer-related deaths worldwide and in the United States. Despite recent advancements in treatment approaches, metastasis... non small cell lung cancer https://pmc.ncbi.nlm.nih.gov/articles/PMC11430445/ Synergistic Inhibition of Pancreatic Cancer Cell Growth and Migration by Gemcitabine and Withaferin... Pancreatic cancer remains one of the most lethal malignancies due to its aggressive nature and resistance to conventional therapies. This study investigates... pancreatic cancer cell growth https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2018.00195/full Frontiers | Withaferin A Associated Differential Regulation of Inflammatory Cytokines A role of inflammation-associated cytokines/chemokines has been implicated in a wide variety of human diseases. Here, we investigated the regulation of infla... withaferin a frontiers associated differential regulation https://www.mdpi.com/1420-3049/26/24/7696 Withaferin A: From Ancient Remedy to Potential Drug Candidate Withaferin A (WA) is a pivotal withanolide that has conquered a conspicuous place in research, owning to its multidimensional biological properties. It is an... withaferin a ancient remedy potential drug https://www.frontiersin.org/journals/cell-and-developmental-biology/articles/10.3389/fcell.2021.636498/full Frontiers | Withaferin A and Ovarian Cancer Antagonistically Regulate Skeletal Muscle Mass Cachexia is a complex wasting syndrome that overwhelmingly affects the majority of late-stage cancer patients. Additionally, there are currently no efficacio... withaferin a ovarian cancer skeletal muscle frontiers https://pmc.ncbi.nlm.nih.gov/articles/PMC5199013/ Withaferin A Induces ROS-Mediated Paraptosis in Human Breast Cancer Cell-Lines MCF-7 and MDA-MB-231... Advancement in cancer therapy requires a better understanding of the detailed mechanisms that induce death in cancer cells. Besides apoptosis, themode of other... https://pmc.ncbi.nlm.nih.gov/articles/PMC10893887/ Withaferin A inhibits lysosomal activity to block autophagic flux and induces apoptosis via... Withaferin A (WFA), a steroidal lactone, negatively regulates breast cancer growth however, its mechanisms of action remain largely elusive. We found that WFA...