abcb1 - Robuta Search

https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2025.1510890/full Frontiers | Influence of the ABCB1-rs1045642 gene polymorphism on blood drug concentration in... This study aimed to investigate the impact of the ABCB1-rs1045642 gene polymorphism on the blood drug concentrations of voriconazole in patients with severe ... https://pmc.ncbi.nlm.nih.gov/articles/PMC10441638/ ABCB1 and ABCG2 Regulation at the Blood-Brain Barrier: Potential New Targets to Improve Brain Drug... The drug efflux transporters ABCB1 and ABCG2 at the blood-brain barrier limit the delivery of drugs into the brain. Strategies to overcome ABCB1/ABCG2 have... https://www.ncbi.nlm.nih.gov/Structure/cdd/cd18578 CDD Conserved Protein Domain Family: ABC_6TM_Pgp_ABCB1_D2_like cd18578 (PSSM ID: 350022): Conserved Protein Domain Family ABC_6TM_Pgp_ABCB1_D2_like, P-glycoprotein 1 (permeability glycoprotein, Pgp) also known as multidrug... conserved protein cdd domain family https://www.ncbi.nlm.nih.gov/Structure/pdb/7ZK8 7ZK8: ABCB1 L971C mutant (mABCB1) in the outward facing state bound to AAC ATP-dependent translocase... https://www.jci.org/articles/view/70430/figure/1 JCI - P-glycoprotein ABCB1: a major player in drug handling by mammals p glycoprotein a major https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2021.672287/full Frontiers | Clinical Relevance of ABCB1, ABCG2, and ABCC2 Gene Polymorphisms in Chronic Myeloid... Tyrosine kinase inhibitors (TKIs) have radically changed the outcome of chronic myeloid leukemia (CML) patients in the last 20 years. Moreover, the advent of... https://www.ncbi.nlm.nih.gov/Structure/pdb/7A6F 7A6F: Nanodisc reconstituted human ABCB1 in complex with MRK16 Fab and zosuquidar MRK16 Fab-fragment heavy chainMRK16 Fab-fragment light chainMultidrug resistance protein 1CHOLESTEROLZosuquidar https://www.spandidos-publications.com/10.3892/ijo.2017.4005 Uncaria alkaloids reverse ABCB1-mediated cancer multidrug resistance International Journal of Oncology is an international journal devoted to oncology research and cancer treatment. uncaria alkaloids reverse abcb1 mediated https://pmc.ncbi.nlm.nih.gov/articles/PMC8931498/ Drug Transporters ABCB1 (P-gp) and OATP, but not Drug-Metabolizing Enzyme CYP3A4, Affect the... The psychedelic alkaloid ibogaine is increasingly used as an oral treatment for substance use disorders, despite being unlicensed in most countries and having... https://www.mdpi.com/2077-0383/11/19/5655 ABCB1 Is Frequently Methylated in Higher-Grade Gliomas and May Serve as a Diagnostic Biomarker of... ABCB1 belongs to a superfamily of membrane transporters that use ATP hydrolysis to efflux various endogenous compounds and drugs outside the cell. Cancer cells... https://www.ebi.ac.uk/chembl/explore/target/CHEMBL4302 Target: ATP-dependent translocase ABCB1 (CHEMBL4302) - ChEMBL Report card for Target ATP-dependent translocase ABCB1 (CHEMBL4302). Homo sapiens, SINGLE PROTEIN, 7.6.2.1, 7.6.2.2, ABCB1, ATP-binding cassette sub-family B... target atp dependent translocase abcb1 https://www.ncbi.nlm.nih.gov/Structure/cdd/cd18577 CDD Conserved Protein Domain Family: ABC_6TM_Pgp_ABCB1_D1_like cd18577 (PSSM ID: 350021): Conserved Protein Domain Family ABC_6TM_Pgp_ABCB1_D1_like, P-glycoprotein 1 (permeability glycoprotein, Pgp) also known as multidrug... conserved protein cdd domain family