https://www.muni.cz/en/research/publications/1672039
An Explorative Analysis of ABCG2/TOP-1 mRNA Expression as a Biomarker Test for FOLFIRI Treatment in...
https://www.mdpi.com/2227-9059/11/9/2567
ABCC1, ABCG2 and FOXP3: Predictive Biomarkers of Toxicity from Methotrexate Treatment in Patients...
Background: Methotrexate (MTX) is one of the most extensively used drugs in the treatment of moderate-to-severe psoriasis (PS). However, it frequently must be...
https://pmc.ncbi.nlm.nih.gov/articles/PMC10441638/
ABCB1 and ABCG2 Regulation at the Blood-Brain Barrier: Potential New Targets to Improve Brain Drug...
The drug efflux transporters ABCB1 and ABCG2 at the blood-brain barrier limit the delivery of drugs into the brain. Strategies to overcome ABCB1/ABCG2 have...
https://www.rcsb.org/structure/6HBU
RCSB PDB - 6HBU: Cryo-EM structure of the ABCG2 E211Q mutant bound to ATP and Magnesium
Cryo-EM structure of the ABCG2 E211Q mutant bound to ATP and Magnesium
https://www.rcsb.org/structure/8QCM
RCSB PDB - 8QCM: ABCG2 in complex with MZ82 and 5D3 Fab
ABCG2 in complex with MZ82 and 5D3 Fab
rcsb pdbabcg2
https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2021.672287/full
Frontiers | Clinical Relevance of ABCB1, ABCG2, and ABCC2 Gene Polymorphisms in Chronic Myeloid...
Tyrosine kinase inhibitors (TKIs) have radically changed the outcome of chronic myeloid leukemia (CML) patients in the last 20 years. Moreover, the advent of...
https://www.spandidos-publications.com/10.3892/or.2011.1468/abstract
Arginine 482 to glycine mutation in ABCG2/BCRP increases etoposide transport and resistance to the...
Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.
https://elifesciences.org/articles/83976/figures
Figures and data in Nucleotide binding is the critical regulator of ABCG2 conformational...
The conformational switch of ABCG2 from the high substrate affinity inward-facing to a low substrate affinity outward-facing state is induced by nucleotide...
https://www.ncbi.nlm.nih.gov/Structure/pdb/7NEZ
7NEZ: Structure of topotecan-bound ABCG2
5D3(Fab) heavy chain variable domain5D3(Fab) light chain variable domainATP-binding cassette sub-family G member...
structuretopotecanboundabcg2
https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2013.00138/full
Frontiers | ABCG2 is not able to catalyze glutathione efflux and does not contribute to...
ABCG2 is a key human ATP-Binding Cassette (ABC) transporter mediating cancer cell chemoresistance. In the case of ABCC1, another multidrug transporter, earli...
is not
https://www.spandidos-publications.com/mmr/5/3/603
Differential effects of calcium antagonists on ABCG2/BCRP-mediated drug resistance and transport in...
Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.