Robuta

As a member of the wwPDB, the RCSB PDB curates and annotates PDB data according to agreed upon standards. The RCSB PDB also provides a variety of tools and...

Crystal structure of human Karyopherin-beta2 bound to the PY-NLS of Saccharomyces cerevisiae NAB2

PanDDA analysis group deposition -- Crystal Structure of Enterovirus D68 3C Protease in complex with Z44585777

Structure of the enzyme-product complex resulting from TDG action on a GT mismatch in the presence of excess base

Crystal structure of oxidized C73S/C85S putidaredoxin, a [2Fe-2S] ferredoxin from Pseudomonas putida

Cryo-electron Tomography and All-atom Molecular Dynamics Simulations Reveal a Novel Kinase Conformational Switch in Bacterial Chemotaxis Signaling

Spatial structure of P33A mutant of non-conventional toxin WTX from Naja kaouthia

Solution Structure of the Band 7 Domain of the mouse Flotillin 2 Protein

Structure of G132S BlaC from Mycobacterium tuberculosis

Bovine Pancreatic Trypsin with 6-Methoxytryptamine (Cryo)

Crystal structure of the porcine OAS1 L149R mutant in complex with dsRNA and ApCpp in the AMP donor position

Ensemble refinement of the protein crystal structure of gene product from Arabidopsis thaliana At4g09670

Crystal structure of 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase (hisA).

Transcription factor GRDBD and smGRE complex

Non-square conformations of KtrA E125Q mutant rings with bound ADP

Crystal structure of HCoV 229E main protease in complex with PF07304814

Structure of Human Serum Albumin

Mutant R1722W of the dihydroorotase domain of human CAD protein bound to the inhibitor fluoorotate

Structure of the star domain of T-STAR in complex with AUUAAA RNA

Crystal structure of CTX-M-14 E166A/K234R Beta-lactamase in complex with hydrolyzed ampicillin

Crystal Structure of PAS-GAF domain of the phytochrome from Deinococcus radiodurans at femto and picosecond timescales (-33 fs)

Identification of N-(4-((1R,3S,5S)-3-amino-5-methylcyclohexyl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide (PIM447), a Potent and Selective...

ROR(gamma)t ligand binding domain in complex with cholesterol and allosteric ligand MRL871

compound 1a bound KMT9 crystal structure

O-acety-L-homoserine aminocarboxypropyltransferase (MetY) from Thermotoga maritima with pyridoxal-5-phosphate (PLP) bound in the internal aldimine state

Brr2 Helicase Region S1087L, Mg-ATP

Crystal Structure of RSV strain B18537 Prefusion-stabilized glycoprotein F Variant DS-Cav1

STING C-terminal Domain Complexed with Non-cyclic Dinucleotide Compound 3

Ligand binding to FARNESOID-X-RECEPTOR

Crystal structure of human carbonic anhydrase isozyme II with 4-[N-(6-chloro-5-formyl-2-methylthiopyrimidin-4-yl)amino]benzenesulfonamide

Structure of Native Human Beta B2 Crystallin

MET receptor in complex with InlB internalin domain and DARPin A3A

Structural and DNA binding studies of the transcriptional repressor Rv2506 (BkaR) from Mycobacterium tuberculosis supports a role in L-Leucine catabolism

Crystal structure of AbnA, a GH43 extracellular arabinanase from Geobacillus stearothermophilus, in complex with arabinopentaose

Ligand complex of RORg LBD

The complex structure of extracellular domain of EGFR and GC1118A

Structure of the complex of type 1 Ribosome inactivating protein with triethanolamine at 1.88 Angstrom resolution

ligand complex structure of soluble epoxide hydrolase

Crystal structure of the in-line aligned env22 twister ribozyme

NMR STRUCTURE OF CTX A3 AT NEUTRAL PH (20 STRUCTURES)

Plasmodium falciparum M1 aminopeptidase bound to MMV1557817

Crystal structure of putative 3-ketoacyl-(acyl-carrier-protein) reductase from Vibrio cholerae O1 biovar eltor str. N16961 in complex with NADP+

Discovery of Epigenetic Regulator I-BET762: Lead Optimization to Afford a Clinical Candidate Inhibitor of the BET Bromodomains

Solution structure of branaplam bound to the RNA duplex formed upon 5'-splice site recognition

Crystal structure of Bovine Serum Albumin

CRYSTAL STRUCTURE OF THE HUMAN CDKL1 KINASE DOMAIN

Structural basis for the dsRNA specificity of the Lassa virus NP exonuclease

Crystal structure of the complex formed between phospholipase A2 and 1, 2 benzopyrone at 2.4 A resolution

Crystal structure of HCV NS3/4A D168A protease in complex with P4-5 (NR01-97)

Human Carbonic Anhydrase II in complex with fluorinated benzenesulfonamide

Structure of the Cmr2 subunit of the CRISPR RNA silencing complex

Leishmania ATP-actin monomer in complex with Leishmania profilin

Parkin (S65DUblR0RBR)

PanDDA analysis group deposition -- Crystal Structure of JMJD2D after initial refinement with no ligand modelled (structure 89)

Crystal structure of PETase S121E/P181V/D186H/N233C/S242T/N246D/S282C mutant from Ideonella sakaiensis

apo ADC-33 beta-lactamase

Endothiapepsin in complex with fragment 17

Crystal structure of CREBBP bromodomain complexed with LA36

SARA CoV-2 3C-like protease in complex with GSK3487016A

Structure basis of inactivating cell abscission with chimera peptide 1

Crystal structure of a putative transcriptional regulator from Saccharomonospora viridis in complex with N,N-dimethylmethanamine

Human Argonaute2-miR-122 bound to a target RNA with two central mismatches (bu2)

Crystal structure of C. elegans LGG-2 bound to an AIM/LIR motif

Isoform-specific inhibition of SUMO-dependent protein-protein interactions

p53 cancer mutant Y220C in complex with compound MB487

Crystal structure of Leishmania major fructose-1,6-bisphosphatase in apo form.

crystal structure of Arabidopsis thaliana JMJ14 catalytic domain

Human CEACAM6-CEACAM8 N-domain heterodimer complex

Crystal structure of rabbit muscle aldolase-SNX9 LC4 complex

Crystal structure of ACK1 with compound 10d

Crystal Structure of L-amino acid oxidase from venom of Naja atra

PQR530 [(S)-4-(Difluoromethyl)-5-(4-(3-methylmorpholino)-6-morpholino-1,3,5-triazin-2-yl)pyridin-2-amine] bound to the PI3Ka catalytic subunit p110alpha

Crystal structure of the CNNM2 CBS-pair domain in complex with ARL15

Automated refinement of diffraction data obtained from an endothiapepsin crystal treated with fragment 11

The crystal structure of neuraminidase in complex with sialic acid from A/Shanghai/2/2013 (H7N9) influenza virus

Crystal structure of the 3-keto-5-aminohexanoate cleavage enzyme (Kce) from C. Cloacamonas acidaminovorans in complex with the product acetoacetate

Structure of a partial yeast 48S preinitiation complex in closed conformation

Crystal structure of GRL-8234 bound to BACE (Beta-secretase)

Atomic Resolution Structure of Monomorphic AB42 Amyloid Fibrils

Chicken villin subdomain HP-35, N68H, pH6.4

Ki67-PP1g (protein phosphatase 1, gamma isoform) holoenzyme complex

Crystal structure of Ser/Thr kinase Pim1 in complex with thioridazine derivatives

Human Xylosyltransferase 1 in complex with peptide QEEEGSGGGQGG

Crystal structure of the Abl-SH3 domain at pH5

The ankyrin repeat domain of Huntingtin interacting protein 14

Joint neutron and x-ray crystal structure of human carbonic anhydrase IX mimic (saccharin-sugar conjugate complex)

Beta-N-acetylgalactosaminidase from Niabella aurantiaca

Crystal structure of the SWIRM domain of human histone lysine-specific demethylase LSD1

Structure of TYK2 with inhibitor 4: 3-azanyl-5-(2-methylphenyl)-7-(1-methylpyrazol-3-yl)-1~{H}-pyrazolo[4,3-c]pyridin-4-one

Crystal structure of PIP4KIIBETA F205L complex with AMP

Fitted model of staphylococcus aureus sav1866 model ABC transporter in the human cystic fibrosis transmembrane conductance regulator volume map EMD-1966.

CryoEM structure of anti-MHC-I mAb B1.23.2 complex with HLA-B44:05

Cryo-EM of the S. islandicus filamentous virus, SIFV

Crystal structure of human AK4(L171P)

Dickeya chrysanthemi complex with L-Asp at pH 5.6

Design and Optimization of Biaryl Ether Aryl Sulfonamides as Selective Inhibitors of NaV1.7: Discovery of Clinical Candidate PF-05089771

crystal structure of the phenol-responsive sensory domain of the transcription activator PoxR with 3,4-dimethylphenol

Crystal structure of Mumps virus hemagglutinin-neuraminidase bound to 3-sialyllactose

PanDDA analysis group deposition -- Endothiapepsin changed state model for fragment F2X-Entry Library C11b