https://pmc.ncbi.nlm.nih.gov/articles/PMC7231988/
Allopregnanolone in premenstrual dysphoric disorder (PMDD): Evidence for dysregulated sensitivity...
Premenstrual dysphoric disorder (PMDD) is a severe mood disorder with core symptoms (affective lability, irritability, depressed mood, anxiety) and increased...
dysphoric disorderallopregnanolonepremenstrualpmddevidence
https://pmc.ncbi.nlm.nih.gov/articles/PMC3648625/
Allopregnanolone Elevations Following Pregnenolone Administration are Associated with Enhanced...
The neurosteroid allopregnanolone is a potent allosteric modulator of the GABA(A) receptor with anxiolytic properties. Exogenous administration of...
associated withallopregnanoloneelevationsfollowingpregnenolone
https://pmc.ncbi.nlm.nih.gov/articles/PMC8197074/
The Role of HPA Axis and Allopregnanolone on the Neurobiology of Major Depressive Disorders and...
Under stressful conditions, the hypothalamic-pituitary-adrenal (HPA) axis acts to promote transitory physiological adaptations that are often resolved after...
the rolehpa axis
https://www.businesswire.com/news/home/20211208005277/en/PureTech-Presents-Preclinical-Proof-of-Concept-Data-for-LYT-300-Oral-Allopregnanolone-as-Potential-Treatment-for-Neurological-and-Neuropsychological-Conditions
PureTech Presents Preclinical Proof-of-Concept Data for LYT-300 (Oral Allopregnanolone) as...
PureTech presented preclinical proof-of-concept data at the ACNP Annual Meeting that support the clinical advancement of LYT-300.
proof of concept
https://pmc.ncbi.nlm.nih.gov/articles/PMC6594874/
Allopregnanolone and Reproductive Psychiatry: An Overview - PMC
Psychiatric symptoms that coincide with reproductive transitions are related to changes in sex steroids, but studies show that this relationship is governed by...
reproductive psychiatryan overviewallopregnanolonepmc