allosteric inhibitor - Robuta Search

https://www.ncbi.nlm.nih.gov/Structure/pdb/6UXX 6UXX: PRMT5:MEP50 Complexed with Allosteric Inhibitor Compound 1a Methylosome protein 50Protein arginine N-methyltransferase... allosteric inhibitor prmt5 compound 1a https://www.mdpi.com/1420-3049/30/6/1341 Isolation of Allosteric Tryptase Inhibitor from Methanol Extract of Rhubarb and Enhancement of Its... Tryptase, which is abundant in human mast cells and is involved in allergic inflammations such as asthma, is a serine protease. We isolated a tryptase... https://www.rcsb.org/structure/4FGT RCSB PDB - 4FGT: Allosteric peptidic inhibitor of human thymidylate synthase that stabilizes... Allosteric peptidic inhibitor of human thymidylate synthase that stabilizes inactive conformation of the enzyme. rcsb pdb https://www.rcsb.org/structure/1SHL RCSB PDB - 1SHL: CASPASE-7 IN COMPLEX WITH FICA ALLOSTERIC INHIBITOR CASPASE-7 IN COMPLEX WITH FICA ALLOSTERIC INHIBITOR rcsb pdb caspase 7 https://www.rcsb.org/structure/6N7Z RCSB PDB - 6N7Z: Crystal structure of human FPPS in complex with an allosteric inhibitor YF-02037 Crystal structure of human FPPS in complex with an allosteric inhibitor YF-02037 https://www.ebi.ac.uk/chembl/explore/document/CHEMBL4699491 Document: Identification of TNO155, an Allosteric SHP2 Inhibitor for the Treatment of Cancer.... Report card for Document Identification of TNO155, an Allosteric SHP2 Inhibitor for the Treatment of Cancer. (CHEMBL4699491). J Med Chem, SHP2 is a nonreceptor... https://elifesciences.org/articles/65339/peer-reviews Peer review in Uncovering an allosteric mode of action for a selective inhibitor of human Bloom... Discovery and characterisation of a novel allosteric inhibitor-binding site in human Bloom syndrome protein.