https://scholars.duke.edu/publication/1565282
Scholars@Duke publication: Aptamer-programmable adeno-associated viral vectors as a novel platform...
https://www.cancer.gov/publications/dictionaries/cancer-drug/def/anti-nucleolin-aptamer-as1411
Definition of anti-nucleolin aptamer AS1411 - NCI Drug Dictionary - NCI
Find technical definitions and synonyms by letter for drugs/agents used to treat patients with cancer or conditions related to cancer. Each entry includes...
definition ofantiaptamerncidrug
https://uwspace.uwaterloo.ca/items/3fa75f1a-b051-4d32-9cd4-791792303851
Homogeneous assays for aptamer-based ethanolamine sensing: no indication of target binding
Ethanolamine is an important analyte for environmental chemistry and biological sciences. A few DNA aptamers were previously reported for binding ethanolamine...
https://scholars.duke.edu/publication/917191
Scholars@Duke publication: AN RNA APTAMER IS A POTENTIAL BIOMARKER FOR PANCREATIC CANCER
https://scholars.duke.edu/publication/1667755
Scholars@Duke publication: Improving Aptamer Affinity and Determining Sequence-Activity...
scholarsdukepublicationimprovingaptamer
https://pubmed.ncbi.nlm.nih.gov/31953175/
Single-stranded DNA (ssDNA) Aptamer targeting SipA protein inhibits Salmonella Enteritidis invasion...
Salmonella Enteritidis is an important pathogen that can invade the intestinal cells of its host causing salmonellosis. SipA protein, an effector protein...
https://experts.umn.edu/en/publications/aptamer-micelles-targeting-fractalkine-expressing-cancer-cells-in/
Aptamer micelles targeting fractalkine-expressing cancer cells in vitro and in vivo -...
cancer cellsin vitroaptamermicellestargeting
https://nij.ojp.gov/library/publications/aptamer-based-exonuclease-amplified-paper-device-point-collection-screening
Aptamer-Based, Exonuclease-Amplified, Paper Device for Point of Collection Screening of Cocaine and...
In order to simultaneously detect trace amounts of drug molecules in oral fluid with high specificity, this project proposed a colorimetric detection platform...
https://uwspace.uwaterloo.ca/items/318020ea-b52b-457a-88d0-0a686cb0d187
Multiplexed SELEX for Sulfonamide Antibiotics Yielding a Group-Specific DNA Aptamer for Biosensors
The widespread use of sulfonamide (SA) antibiotics in animal husbandry has led to residues of SAs in the environment, causing adverse effects to the ecosystem...
https://scholars.duke.edu/publication/1567009
Scholars@Duke publication: Rapid molecular imaging of active thrombi in vivo using aptamer-antidote...
https://pubmed.ncbi.nlm.nih.gov/28453726/
Osteopontin RNA aptamer can prevent and reverse pressure overload-induced heart failure
Taken together, these data demonstrate that tuning down cardiac OPN signalling by an OPN RNA aptamer is a novel and effective approach for preventing cardiac...
https://uwspace.uwaterloo.ca/items/06a2a1c7-b4d3-4089-87ad-6bb7dcd9e849
Stimuli-responsive releasing of gold nanoparticles and liposomes from aptamer-functionalized...
Controlled release of therapeutic agents is important for improving drug efficacy and reducing toxicity. Recently, hydrogels have been used for controlled...
gold nanoparticlesstimuliresponsivereleasing
https://pubmed.ncbi.nlm.nih.gov/33561300/
Aptamer Blocking Strategy Inhibits SARS-CoV-2 Virus Infection
The COVID-19 pandemic caused by SARS-CoV-2 is threating global health. Inhibiting interaction of the receptor-binding domain of SARS-CoV-2 S protein...
sars covaptamerblockingstrategyvirus
https://nij.ojp.gov/library/publications/rapid-and-reliable-site-drug-detection-using-aptamer-based-sensors
Rapid and Reliable On-Site Drug Detection Using Aptamer-based Sensors | National Institute of...
This fact sheet reports on a NIJ-funded study that developed a rapid and reliable field test for identifying illegal drugs in oral fluids that is superior to...
https://scholars.duke.edu/grant/252335
Scholars@Duke grant: Reducing prostate cancer aggressiveness via aptamer-mediated nuclear delivery...
prostate cancer
https://uwspace.uwaterloo.ca/items/ad66537d-fb40-462e-8186-645c17d9c39c
Exploring Ligand Structure and Thermodynamics of the Malachite Green RNA Aptamer
RNA aptamers are in vitro sequences of RNA that have a high affinity for their target ligand. They have applications in therapeutics, biosensors and molecular...
of themalachite greenexploringstructurethermodynamics
https://pubs.rsc.org/en/content/articlelanding/2023/cs/d3cs00030c
Harmonizing the growing fluorogenic RNA aptamer toolbox for RNA detection and imaging - Chemical...
The field of fluorogenic RNA aptamers is a burgeoning research area that aims to address the lack of naturally fluorescent RNA molecules for RNA detection and...
https://pubmed.ncbi.nlm.nih.gov/38927112/
Myogenic Anti-Nucleolin Aptamer iSN04 Inhibits Proliferation and Promotes Differentiation of...
De-differentiation and subsequent increased proliferation and inflammation of vascular smooth muscle cells (VSMCs) is one of the mechanisms of atherogenesis....
antiaptamer
https://pubmed.ncbi.nlm.nih.gov/38012811/
An Aptamer-Based Nanoflow Cytometry Method for the Molecular Detection and Classification of...
Molecular profiling of protein markers on small extracellular vesicles (sEVs) is a promising strategy for the precise detection and classification of ovarian...
https://iris.cnr.it/handle/20.500.14243/332451
Aptamer-mediated impairment of EGFR-integrin alpha v beta 3 complex inhibits vasculogenic mimicry...
https://scholars.duke.edu/publication/800973
Scholars@Duke publication: Antidote control of aptamer therapeutics: the road to a safer class of...
https://uwspace.uwaterloo.ca/items/af152799-f72c-46a3-9309-941bcea45730
A DNA Aptamer for Theophylline with Ultrahigh Selectivity Reminiscent of the Classic RNA Aptamer
Since the report of the RNA aptamer for theophylline, theophylline has become a key molecule in chemical biology for designing RNA switches and riboswitches....
https://scholars.duke.edu/publication/1004694
Scholars@Duke publication: Systemic administration of optimized aptamer-siRNA chimeras promotes...
scholarsdukepublicationsystemicadministration
https://researchconnect.buffalo.edu/en/publications/a-quantum-dot-aptamer-beacon-using-a-dna-intercalating-dye-as-the/
A quantum dot-aptamer beacon using a DNA intercalating dye as the FRET reporter: Application to...
https://scholars.duke.edu/publication/1314158
Scholars@Duke publication: Tunable cytotoxic aptamer-drug conjugates for the treatment of prostate...
https://pubmed.ncbi.nlm.nih.gov/37750217/
Recent advances in aptamer-based biosensors for potassium detection
Maintaining a stable level of potassium is crucial for proper bodily function because even a slight imbalance can result in serious disorders like hyperkalemia...
recent advancesaptamerbasedbiosensorspotassium
https://www.ncbi.nlm.nih.gov/Structure/pdb/7ZJ4
7ZJ4: Ligand bound state of a brocolli-pepper aptamer FRET tile
brocolli-pepper...
state ofbound
https://pubmed.ncbi.nlm.nih.gov/32200887/
DNA aptamer-based non-faradaic impedance biosensor for detecting E. coli
Developing a real-time, portable, and inexpensive sensor for pathogenic bacteria is crucial since the conventional detection approaches such as enzyme-linked...
dnaaptamerbasednon
https://eprints.soton.ac.uk/146695/
Binding of 14-3-3 proteins to a single stranded oligodeoxynucleotide aptamer - ePrints Soton
https://www.ncbi.nlm.nih.gov/Structure/pdb/8GZL
8GZL: Crystal structure of Cd2+-bound DNA aptamer
25-mer DNABARIUM IONCADMIUM ION
crystal structurebounddnaaptamer
https://nij.ojp.gov/topics/articles/rapid-and-reliable-site-drug-detection-using-aptamer-based-sensors
Rapid and Reliable On-Site Drug Detection Using Aptamer-based Sensors | National Institute of...
Noting the widespread need for rapid and reliable detection of illicit drugs by police and medical personnel, researchers with Florida International University...
https://publications-cnrc.canada.ca/fra/voir/objet/?id=42c64799-1534-46da-8776-5c4a49f39106
Multivalent aptamer meshed open pore membrane and signal amplification for high-flux and ultra...
Multivalent aptamer meshed open pore membrane and signal amplification for high-flux and ultra sensitive whole cell detection of E. coli O157:H7 in complex...
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0153637
Isolation of an Aptamer that Binds Specifically to E. coli | PLOS One
Escherichia coli is a bacterial species found ubiquitously in the intestinal flora of animals, although pathogenic variants cause major public health problems....
https://www.ncbi.nlm.nih.gov/Structure/pdb/8HZK
8HZK: A new fluorescent RNA aptamer bound with N, iridium hexammine soak
a new
https://uwspace.uwaterloo.ca/items/ef85efc5-9a7c-4418-a896-c7079ccf384b
Mucin-targeting-aptamer functionalized liposomes for delivery of cyclosporin A for dry eye diseases
Traditional eye drops are convenient to use; however, their effectiveness is limited by their poor retention time and bioavailability in the eyes due to ocular...
https://scholars.duke.edu/grant/210904
Scholars@Duke grant: Aptamer-based affinity capture of circulating CAD EPCs
scholarsdukegrantaptamerbased
https://portal.fis.tum.de/en/publications/out-of-plane-aptamer-functionalization-of-rna-three-helix-tiles/
Out-of-plane aptamer Functionalization of RNA three-helix tiles - Technical University of Munich
out of
https://events.diabetes.org/p/s/aptamer-driven-immunomodulation-of-human-islets-combating-ibmir-for-clinical-translation-5743
Aptamer-Driven Immunomodulation of Human Islets: Combating IBMIR for Clinical Translation -...
aptamerdrivenimmunomodulationhuman
https://scholars.duke.edu/publication/1034790
Scholars@Duke publication: 83. Cell_Type Specific Delivery of siRNAs with Aptamer_siRNA Chimeras
https://nij.ojp.gov/library/publications/developing-aptamer-based-colorimetric-opioid-tests
Developing Aptamer-Based Colorimetric Opioid Tests | National Institute of Justice
This publication discusses the development of aptamer-based colorimetric opioid tests.
national institutedevelopingaptamerbasedcolorimetric
https://nij.ojp.gov/funding/awards/2019-du-bx-0024
Electrochemical Aptamer-Based Sensor for Rapid Opioid Detection in Seized Substances | National...
Opioids are a class of highly addictive and dangerous drugs that can cause severe health consequences and death. The US is currently facing the worst drug...
https://pubmed.ncbi.nlm.nih.gov/19235795/
DNA aptamer-passivated nanocrystal synthesis: a facile approach for nanoparticle-based cancer cell...
DNA aptamer-passivated nanocrystal synthesis: a facile approach for nanoparticle-based cancer cell growth inhibition
https://www.mdpi.com/2313-5786/5/2/11
Aptamer-Enhanced Surface Decontamination: A Novel Approach for Neutralizing Peanut Allergens and...
Peanut allergies, driven by sensitization to key allergens Ara h1, Ara h2, and Ara h3, present significant health risks, particularly in food processing and...
a novel approachsurface decontamination
https://scholars.duke.edu/publication/967501
Scholars@Duke publication: Further characterization of the target of a potential aptamer biomarker...
of the
https://scholars.duke.edu/publication/720449
Scholars@Duke publication: Antidote-mediated control of an anticoagulant aptamer in vivo.
https://www.invenio-medical.com/
Invenio Medical — Aptamer diagnostics for the point of care
Invenio Medical develops AptaSure™, an aptamer-based rapid point-of-care test. A cognate aptamer pair binds the MRSA resistance protein pbp2a for a...
for thepoint ofinveniomedicalaptamer
https://research.tue.nl/en/studentTheses/optical-detection-of-crp-binding-to-aptamer-functionalized-single/
Optical detection of CRP binding to aptamer functionalized single gold nanorods - Research portal...
https://pure.york.ac.uk/portal/en/publications/an-rna-aptamer-based-assay-for-the-detection-and-analysis-of-mala/
An RNA Aptamer Based Assay for the Detection and Analysis of Malachite Green and Leucomalachite...
https://cordis.europa.eu/project/id/101150621/fr
Malaria diagnosis and prognosis with an electrokinetic-driven aptamer-based lateral flow assay. |...
Malaria remains a public health concern, with 247 million cases and 619,000 deaths reported globally in 2021. Despite the increasing prevention and control...
diagnosis and prognosis
https://scholars.duke.edu/publication/782650
Scholars@Duke publication: A reversible aptamer improves outcome and safety in murine models of...
https://uwspace.uwaterloo.ca/items/17bace3c-3a73-4e0d-9eef-f5e0b68b94d0
Signaling Kinetics of DNA and Aptamer Biosensors Revealing Graphene Oxide Surface Heterogeneity
Adsorption of fluorescently labeled DNA and aptamer probes to graphene oxide (GO) has been one of the most popular methods for developing biosensors. In the...
https://drum.lib.umd.edu/items/c627df09-f23f-4392-b994-ff05071faab2
Aptamer Selection for DNA Aptamers against Glioblastoma Biomarker
Glioblastoma is an extremely invasive and deadly form of brain cancer, with median survival rates, after diagnosis, only being one year. Current diagnostics...
aptamerselectiondnaglioblastomabiomarker
https://researchconnect.buffalo.edu/en/publications/signal-on-protein-detection-via-dye-translocation-between-aptamer/
Signal-on Protein Detection via Dye Translocation between Aptamer and Quantum Dot - SUNY University...
https://scholars.duke.edu/publication/1127829
Scholars@Duke publication: A novel aptamer targeting agent for prostate cancer
a novelscholarsdukepublication
https://vivo.colorado.edu/display/pubid_57124
Aptamer-Crosslinked Microbubbles: Smart Contrast Agents for Thrombin-Activated Ultrasound Imaging |...
contrast agentsaptamermicrobubblessmart
https://vivo.colorado.edu/display/pubid_33314
Aptamer-Based Multiplexed Proteomic Technology for Biomarker Discovery | CU Experts | CU Boulder
biomarker discoveryaptamerbasedmultiplexedproteomic
https://uwspace.uwaterloo.ca/items/5be75b44-0b3e-4a40-9330-a2fa05fc86d7
An aptamer array for discriminating tetracycline antibiotics based on binding-enhanced intrinsic...
Tetracyclines are a class of antibiotics with a similar four-ringed structure. Due to this structural similarity, they are not easily differentiated from each...
https://pubmed.ncbi.nlm.nih.gov/26859550/
Delivery, Effect on Cell Viability, and Plasticity of Modified Aptamer Constructs
AS1411 is a g-quadruplex-forming aptamer capable of selectively entering cancer cells by nucleolin receptor-mediated uptake. In this study, we investigated the...
cell viabilitydeliveryeffect
https://nij.ojp.gov/library/publications/aptamer-based-paper-microfluidic-device-colorimetric-determination-cocaine
An Aptamer-based Paper Microfluidic Device for the Colorimetric Determination of Cocaine | National...
This article reports on the development of a method that uses paper microfluidics coupled with gold nanoparticles and two anticocaine aptamers to detect seized...
https://publications-cnrc.canada.ca/eng/view/object/?id=c5414c9b-5302-4caa-a514-b2759c8ba8a1
Development of an anti-vascular cell adhesion protein-1 aptamer for molecular imaging and...
Development of an anti-vascular cell adhesion protein-1 aptamer for molecular imaging and inflammation detection in transgenic mouse model of Alzheimer's...
https://nij.ojp.gov/library/publications/label-free-aptamer-fluorophore-assembly-rapid-and-specific-detection-cocaine
An Label-Free Aptamer-Fluorophore Assembly for Rapid and Specific Detection of Cocaine in Biofluids...
This article reports a rapid and specific aptamer-based method for one-step cocaine detection with minimal reagent requirements.
https://scholars.duke.edu/grant/285394
Scholars@Duke grant: Reducing prostate cancer aggressiveness via aptamer-mediated nuclear delivery...
prostate cancer
https://publikationen.uni-tuebingen.de/xmlui/handle/10900/36117?show=full
Identification of an Aptamer Binding to Human Osteogenic-Induced Progenitor Cells
identificationaptamerbinding
https://www.mdpi.com/1420-3049/30/9/2012
Early-Stage Pancreatic Cancer Diagnosis: Serum Biomarkers and the Potential for Aptamer-Based...
Pancreatic cancer has a high mortality rate, and both the incidence and mortality are continuing to increase in many countries globally. The poor prognosis of...
https://www.mdpi.com/1424-8220/22/3/1281
A Simple Yet Effective Preanalytical Strategy Enabling the Application of Aptamer-Conjugated Gold...
The misuse of antibiotics in the cattle sector can lead to milk contamination, with concomitant effects on the dairy industry and human health. Biosensors can...
https://experts.mcmaster.ca/scholarly-works/2775073
Engineering a Ligase Binding DNA Aptamer into a...
Learn about the scholarly work entitled Engineering a Ligase Binding DNA Aptamer into a...
engineeringligasebindingdnaaptamer
https://pure.psu.edu/en/publications/a-gapmer-aptamer-nanobiosensor-for-real-time-monitoring-of-transc/
A gapmer aptamer nanobiosensor for real-time monitoring of transcription and translation in single...
https://www.news-medical.net/news/20090806/Reversible-cell-specific-drug-delivery-with-aptamer-functionalized-liposomes.aspx
Reversible cell-specific drug delivery with aptamer-functionalized liposomes
Jun 19, 2019 - For cancer drug developers, finding an agent that kills tumor cells is only part of the equation. The drug must also spare healthy cells, and - ideally - its...
drug deliveryreversiblecellspecificaptamer
https://nij.ojp.gov/library/publications/aptamer-integrated-multianalyte-detecting-paper-electrochemical-device
Aptamer-Integrated Multianalyte-Detecting Paper Electrochemical Device | National Institute of...
Using oligonucleotide-based aptamers as biorecognition elements, we here for the first time have developed a simple, inexpensive procedure for the fabrication...
national instituteaptamerintegrateddetectingpaper
https://portal.fis.tum.de/en/publications/fluorescence-activated-cell-sorting-for-aptamer-selex-with-cell-m/
Fluorescence-activated cell sorting for aptamer SELEX with cell mixtures - Technical University of...
cell sorting
https://research.utwente.nl/en/publications/aptamer-based-spatiotemporally-controlled-growth-factor-patternin/
Aptamer based spatiotemporally controlled growth factor patterning for tunable local microvascular...
growth factoraptamerbasedcontrolled
https://bwrc.berkeley.edu/publications/design-and-analysis-sample-and-hold-cmos-electrochemical-sensor-aptamer-based
Design and Analysis of a Sample-and-Hold CMOS Electrochemical Sensor for Aptamer-Based Therapeutic...
design and analysis
https://pubs.rsc.org/en/content/articlelanding/2020/sc/d0sc03920a
A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking...
Rapid and accurate diagnosis of COVID-19 plays an essential role in the current epidemic prevention and control. Despite the promise of nucleic acid and...
https://pure.psu.edu/en/projects/three-dimensional-one-step-aptamer-selection-in-the-non-fouling-m/
Three-dimensional One-step Aptamer Selection in the Non-fouling Macroporous Hydrogel - Penn State
https://pubmed.ncbi.nlm.nih.gov/39779896/
Sialic acid aptamer and RNA in situ hybridization-mediated proximity ligation assay for spatial...
Glycosylated RNAs (glycoRNAs) have recently emerged as a new class of molecules of substantial interest owing to their potential roles in cellular processes...
https://scholars.duke.edu/publication/1638793
Scholars@Duke publication: An RNA aptamer exploits exosite-dependent allostery to achieve specific...
https://necat.chem.cornell.edu/compact-stem-loop-dna-aptamer-targets-uracil-binding-pocket-sars-cov-2-nucleocapsid-rna-binding
A compact stem-loop DNA aptamer targets a uracil-binding pocket in the SARS-CoV-2 nucleocapsid...
https://scholars.cityu.edu.hk/en/publications/real-time-atp-monitoring-in-human-serum-by-a-nanofluidic-device-i/
REAL-TIME ATP MONITORING IN HUMAN SERUM BY A NANOFLUIDIC DEVICE INTEGRATED WITH AN APTAMER SENSOR -...
https://dukespace.lib.duke.edu/items/04590f08-e790-4076-9ff7-bc51e3458bab
Development of universal antidotes to control aptamer activity.
With an ever increasing number of people taking numerous medications, the need to safely administer drugs and limit unintended side effects has never been...
developmentuniversalantidotescontrolaptamer
https://pubs.rsc.org/en/Content/ArticleLanding/2017/NJ/C7NJ01159H
An ultrasensitive chemiluminescence aptasensor for indirect hemin detection based on aptamer...
In this work, an ultrasensitive chemiluminescence (CL) aptasensor was prepared for indirect hemin detection based on hemin aptamer modified magnetic graphene...
based onultrasensitivechemiluminescence
https://cordis.europa.eu/project/id/707229
Aptamer nanostructures dual-targeted to the HER receptor family for cancer therapy | ADHERE |...
The proposed research programme deals with the development of aptamer nanostructures for targeted cancer therapy. Immunotherapy encompasses a growing field of...
https://experts.umn.edu/en/projects/rapid-poc-toxin-assay-using-aptamer-functionalized-magne/
Rapid POC Toxin Assay using Aptamer-Functionalized Magne - Experts@Minnesota
rapid poctoxinassayusingaptamer
https://pure.psu.edu/en/publications/aptamer-based-molecular-recognition-for-biosensor-development/
Aptamer-based molecular recognition for biosensor development - Penn State
molecular recognitionaptamerbasedbiosensordevelopment
https://pubmed.ncbi.nlm.nih.gov/38111313/
Aptamer Based SPREETA Sensor for the Detection of Porphyromonas gingivalis G-Protein
for the
https://scholars.duke.edu/publication/830341
Scholars@Duke publication: Identification and characterization of an agonistic aptamer against the...
https://publications-cnrc.canada.ca/eng/view/object/?id=9cf619e9-ec28-4d2a-b640-51e6f28ce339
DAPTEV: deep aptamer evolutionary modelling for COVID-19 drug design - NRC Publications Archive -...
DAPTEV: deep aptamer evolutionary modelling for COVID-19 drug design
https://scholars.duke.edu/publication/1568629
Scholars@Duke publication: Aptamer-Small Molecule Conjugates As Potent and Reversible Surgical...
small molecule
https://digital.library.adelaide.edu.au/items/045c1a7f-ef03-46d5-a075-3624e1e3b10c
Aptamer conjugated theragnostic multifunctional magnetic nanoparticles as a nanoplatform for...
Pancreatic cancer is the fifth leading cause of cancer related deaths worldwide. Currently, finding an effective drug delivery strategy in pancreatic cancer...
magnetic nanoparticlesaptamermultifunctional
https://pubchem.ncbi.nlm.nih.gov/bioassay/488806
AID 488806 - RNA aptamer-based validation for inhibitors of GRK2 - PubChem
BioAssay record AID 488806 submitted by NMMLSC: RNA aptamer-based validation for inhibitors of GRK2.
aidrnaaptamerbased