Robuta

https://scholars.duke.edu/publication/1565282 Scholars@Duke publication: Aptamer-programmable adeno-associated viral vectors as a novel platform... https://www.cancer.gov/publications/dictionaries/cancer-drug/def/anti-nucleolin-aptamer-as1411 Definition of anti-nucleolin aptamer AS1411 - NCI Drug Dictionary - NCI Find technical definitions and synonyms by letter for drugs/agents used to treat patients with cancer or conditions related to cancer. Each entry includes... definition ofantiaptamerncidrug https://uwspace.uwaterloo.ca/items/3fa75f1a-b051-4d32-9cd4-791792303851 Homogeneous assays for aptamer-based ethanolamine sensing: no indication of target binding Ethanolamine is an important analyte for environmental chemistry and biological sciences. A few DNA aptamers were previously reported for binding ethanolamine... https://scholars.duke.edu/publication/917191 Scholars@Duke publication: AN RNA APTAMER IS A POTENTIAL BIOMARKER FOR PANCREATIC CANCER https://scholars.duke.edu/publication/1667755 Scholars@Duke publication: Improving Aptamer Affinity and Determining Sequence-Activity... scholarsdukepublicationimprovingaptamer https://pubmed.ncbi.nlm.nih.gov/31953175/ Single-stranded DNA (ssDNA) Aptamer targeting SipA protein inhibits Salmonella Enteritidis invasion... Salmonella Enteritidis is an important pathogen that can invade the intestinal cells of its host causing salmonellosis. SipA protein, an effector protein... https://experts.umn.edu/en/publications/aptamer-micelles-targeting-fractalkine-expressing-cancer-cells-in/ Aptamer micelles targeting fractalkine-expressing cancer cells in vitro and in vivo -... cancer cellsin vitroaptamermicellestargeting https://nij.ojp.gov/library/publications/aptamer-based-exonuclease-amplified-paper-device-point-collection-screening Aptamer-Based, Exonuclease-Amplified, Paper Device for Point of Collection Screening of Cocaine and... In order to simultaneously detect trace amounts of drug molecules in oral fluid with high specificity, this project proposed a colorimetric detection platform... https://uwspace.uwaterloo.ca/items/318020ea-b52b-457a-88d0-0a686cb0d187 Multiplexed SELEX for Sulfonamide Antibiotics Yielding a Group-Specific DNA Aptamer for Biosensors The widespread use of sulfonamide (SA) antibiotics in animal husbandry has led to residues of SAs in the environment, causing adverse effects to the ecosystem... https://scholars.duke.edu/publication/1567009 Scholars@Duke publication: Rapid molecular imaging of active thrombi in vivo using aptamer-antidote... https://pubmed.ncbi.nlm.nih.gov/28453726/ Osteopontin RNA aptamer can prevent and reverse pressure overload-induced heart failure Taken together, these data demonstrate that tuning down cardiac OPN signalling by an OPN RNA aptamer is a novel and effective approach for preventing cardiac... https://uwspace.uwaterloo.ca/items/06a2a1c7-b4d3-4089-87ad-6bb7dcd9e849 Stimuli-responsive releasing of gold nanoparticles and liposomes from aptamer-functionalized... Controlled release of therapeutic agents is important for improving drug efficacy and reducing toxicity. Recently, hydrogels have been used for controlled... gold nanoparticlesstimuliresponsivereleasing https://pubmed.ncbi.nlm.nih.gov/33561300/ Aptamer Blocking Strategy Inhibits SARS-CoV-2 Virus Infection The COVID-19 pandemic caused by SARS-CoV-2 is threating global health. Inhibiting interaction of the receptor-binding domain of SARS-CoV-2 S protein... sars covaptamerblockingstrategyvirus https://nij.ojp.gov/library/publications/rapid-and-reliable-site-drug-detection-using-aptamer-based-sensors Rapid and Reliable On-Site Drug Detection Using Aptamer-based Sensors | National Institute of... This fact sheet reports on a NIJ-funded study that developed a rapid and reliable field test for identifying illegal drugs in oral fluids that is superior to... https://scholars.duke.edu/grant/252335 Scholars@Duke grant: Reducing prostate cancer aggressiveness via aptamer-mediated nuclear delivery... prostate cancer https://uwspace.uwaterloo.ca/items/ad66537d-fb40-462e-8186-645c17d9c39c Exploring Ligand Structure and Thermodynamics of the Malachite Green RNA Aptamer RNA aptamers are in vitro sequences of RNA that have a high affinity for their target ligand. They have applications in therapeutics, biosensors and molecular... of themalachite greenexploringstructurethermodynamics https://pubs.rsc.org/en/content/articlelanding/2023/cs/d3cs00030c Harmonizing the growing fluorogenic RNA aptamer toolbox for RNA detection and imaging - Chemical... The field of fluorogenic RNA aptamers is a burgeoning research area that aims to address the lack of naturally fluorescent RNA molecules for RNA detection and... https://pubmed.ncbi.nlm.nih.gov/38927112/ Myogenic Anti-Nucleolin Aptamer iSN04 Inhibits Proliferation and Promotes Differentiation of... De-differentiation and subsequent increased proliferation and inflammation of vascular smooth muscle cells (VSMCs) is one of the mechanisms of atherogenesis.... antiaptamer https://pubmed.ncbi.nlm.nih.gov/38012811/ An Aptamer-Based Nanoflow Cytometry Method for the Molecular Detection and Classification of... Molecular profiling of protein markers on small extracellular vesicles (sEVs) is a promising strategy for the precise detection and classification of ovarian... https://iris.cnr.it/handle/20.500.14243/332451 Aptamer-mediated impairment of EGFR-integrin alpha v beta 3 complex inhibits vasculogenic mimicry... https://scholars.duke.edu/publication/800973 Scholars@Duke publication: Antidote control of aptamer therapeutics: the road to a safer class of... https://uwspace.uwaterloo.ca/items/af152799-f72c-46a3-9309-941bcea45730 A DNA Aptamer for Theophylline with Ultrahigh Selectivity Reminiscent of the Classic RNA Aptamer Since the report of the RNA aptamer for theophylline, theophylline has become a key molecule in chemical biology for designing RNA switches and riboswitches.... https://scholars.duke.edu/publication/1004694 Scholars@Duke publication: Systemic administration of optimized aptamer-siRNA chimeras promotes... scholarsdukepublicationsystemicadministration https://researchconnect.buffalo.edu/en/publications/a-quantum-dot-aptamer-beacon-using-a-dna-intercalating-dye-as-the/ A quantum dot-aptamer beacon using a DNA intercalating dye as the FRET reporter: Application to... https://scholars.duke.edu/publication/1314158 Scholars@Duke publication: Tunable cytotoxic aptamer-drug conjugates for the treatment of prostate... https://pubmed.ncbi.nlm.nih.gov/37750217/ Recent advances in aptamer-based biosensors for potassium detection Maintaining a stable level of potassium is crucial for proper bodily function because even a slight imbalance can result in serious disorders like hyperkalemia... recent advancesaptamerbasedbiosensorspotassium https://www.ncbi.nlm.nih.gov/Structure/pdb/7ZJ4 7ZJ4: Ligand bound state of a brocolli-pepper aptamer FRET tile brocolli-pepper... state ofbound https://pubmed.ncbi.nlm.nih.gov/32200887/ DNA aptamer-based non-faradaic impedance biosensor for detecting E. coli Developing a real-time, portable, and inexpensive sensor for pathogenic bacteria is crucial since the conventional detection approaches such as enzyme-linked... dnaaptamerbasednon https://eprints.soton.ac.uk/146695/ Binding of 14-3-3 proteins to a single stranded oligodeoxynucleotide aptamer - ePrints Soton https://www.ncbi.nlm.nih.gov/Structure/pdb/8GZL 8GZL: Crystal structure of Cd2+-bound DNA aptamer 25-mer DNABARIUM IONCADMIUM ION crystal structurebounddnaaptamer https://nij.ojp.gov/topics/articles/rapid-and-reliable-site-drug-detection-using-aptamer-based-sensors Rapid and Reliable On-Site Drug Detection Using Aptamer-based Sensors | National Institute of... Noting the widespread need for rapid and reliable detection of illicit drugs by police and medical personnel, researchers with Florida International University... https://publications-cnrc.canada.ca/fra/voir/objet/?id=42c64799-1534-46da-8776-5c4a49f39106 Multivalent aptamer meshed open pore membrane and signal amplification for high-flux and ultra... Multivalent aptamer meshed open pore membrane and signal amplification for high-flux and ultra sensitive whole cell detection of E. coli O157:H7 in complex... https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0153637 Isolation of an Aptamer that Binds Specifically to E. coli | PLOS One Escherichia coli is a bacterial species found ubiquitously in the intestinal flora of animals, although pathogenic variants cause major public health problems.... https://www.ncbi.nlm.nih.gov/Structure/pdb/8HZK 8HZK: A new fluorescent RNA aptamer bound with N, iridium hexammine soak a new https://uwspace.uwaterloo.ca/items/ef85efc5-9a7c-4418-a896-c7079ccf384b Mucin-targeting-aptamer functionalized liposomes for delivery of cyclosporin A for dry eye diseases Traditional eye drops are convenient to use; however, their effectiveness is limited by their poor retention time and bioavailability in the eyes due to ocular... https://scholars.duke.edu/grant/210904 Scholars@Duke grant: Aptamer-based affinity capture of circulating CAD EPCs scholarsdukegrantaptamerbased https://portal.fis.tum.de/en/publications/out-of-plane-aptamer-functionalization-of-rna-three-helix-tiles/ Out-of-plane aptamer Functionalization of RNA three-helix tiles - Technical University of Munich out of https://events.diabetes.org/p/s/aptamer-driven-immunomodulation-of-human-islets-combating-ibmir-for-clinical-translation-5743 Aptamer-Driven Immunomodulation of Human Islets: Combating IBMIR for Clinical Translation -... aptamerdrivenimmunomodulationhuman https://scholars.duke.edu/publication/1034790 Scholars@Duke publication: 83. Cell_Type Specific Delivery of siRNAs with Aptamer_siRNA Chimeras https://nij.ojp.gov/library/publications/developing-aptamer-based-colorimetric-opioid-tests Developing Aptamer-Based Colorimetric Opioid Tests | National Institute of Justice This publication discusses the development of aptamer-based colorimetric opioid tests. national institutedevelopingaptamerbasedcolorimetric https://nij.ojp.gov/funding/awards/2019-du-bx-0024 Electrochemical Aptamer-Based Sensor for Rapid Opioid Detection in Seized Substances | National... Opioids are a class of highly addictive and dangerous drugs that can cause severe health consequences and death. The US is currently facing the worst drug... https://pubmed.ncbi.nlm.nih.gov/19235795/ DNA aptamer-passivated nanocrystal synthesis: a facile approach for nanoparticle-based cancer cell... DNA aptamer-passivated nanocrystal synthesis: a facile approach for nanoparticle-based cancer cell growth inhibition https://www.mdpi.com/2313-5786/5/2/11 Aptamer-Enhanced Surface Decontamination: A Novel Approach for Neutralizing Peanut Allergens and... Peanut allergies, driven by sensitization to key allergens Ara h1, Ara h2, and Ara h3, present significant health risks, particularly in food processing and... a novel approachsurface decontamination https://scholars.duke.edu/publication/967501 Scholars@Duke publication: Further characterization of the target of a potential aptamer biomarker... of the https://scholars.duke.edu/publication/720449 Scholars@Duke publication: Antidote-mediated control of an anticoagulant aptamer in vivo. https://www.invenio-medical.com/ Invenio Medical — Aptamer diagnostics for the point of care Invenio Medical develops AptaSure™, an aptamer-based rapid point-of-care test. A cognate aptamer pair binds the MRSA resistance protein pbp2a for a... for thepoint ofinveniomedicalaptamer https://research.tue.nl/en/studentTheses/optical-detection-of-crp-binding-to-aptamer-functionalized-single/ Optical detection of CRP binding to aptamer functionalized single gold nanorods - Research portal... https://pure.york.ac.uk/portal/en/publications/an-rna-aptamer-based-assay-for-the-detection-and-analysis-of-mala/ An RNA Aptamer Based Assay for the Detection and Analysis of Malachite Green and Leucomalachite... https://cordis.europa.eu/project/id/101150621/fr Malaria diagnosis and prognosis with an electrokinetic-driven aptamer-based lateral flow assay. |... Malaria remains a public health concern, with 247 million cases and 619,000 deaths reported globally in 2021. Despite the increasing prevention and control... diagnosis and prognosis https://scholars.duke.edu/publication/782650 Scholars@Duke publication: A reversible aptamer improves outcome and safety in murine models of... https://uwspace.uwaterloo.ca/items/17bace3c-3a73-4e0d-9eef-f5e0b68b94d0 Signaling Kinetics of DNA and Aptamer Biosensors Revealing Graphene Oxide Surface Heterogeneity Adsorption of fluorescently labeled DNA and aptamer probes to graphene oxide (GO) has been one of the most popular methods for developing biosensors. In the... https://drum.lib.umd.edu/items/c627df09-f23f-4392-b994-ff05071faab2 Aptamer Selection for DNA Aptamers against Glioblastoma Biomarker Glioblastoma is an extremely invasive and deadly form of brain cancer, with median survival rates, after diagnosis, only being one year. Current diagnostics... aptamerselectiondnaglioblastomabiomarker https://researchconnect.buffalo.edu/en/publications/signal-on-protein-detection-via-dye-translocation-between-aptamer/ Signal-on Protein Detection via Dye Translocation between Aptamer and Quantum Dot - SUNY University... https://scholars.duke.edu/publication/1127829 Scholars@Duke publication: A novel aptamer targeting agent for prostate cancer a novelscholarsdukepublication https://vivo.colorado.edu/display/pubid_57124 Aptamer-Crosslinked Microbubbles: Smart Contrast Agents for Thrombin-Activated Ultrasound Imaging |... contrast agentsaptamermicrobubblessmart https://vivo.colorado.edu/display/pubid_33314 Aptamer-Based Multiplexed Proteomic Technology for Biomarker Discovery | CU Experts | CU Boulder biomarker discoveryaptamerbasedmultiplexedproteomic https://uwspace.uwaterloo.ca/items/5be75b44-0b3e-4a40-9330-a2fa05fc86d7 An aptamer array for discriminating tetracycline antibiotics based on binding-enhanced intrinsic... Tetracyclines are a class of antibiotics with a similar four-ringed structure. Due to this structural similarity, they are not easily differentiated from each... https://pubmed.ncbi.nlm.nih.gov/26859550/ Delivery, Effect on Cell Viability, and Plasticity of Modified Aptamer Constructs AS1411 is a g-quadruplex-forming aptamer capable of selectively entering cancer cells by nucleolin receptor-mediated uptake. In this study, we investigated the... cell viabilitydeliveryeffect https://nij.ojp.gov/library/publications/aptamer-based-paper-microfluidic-device-colorimetric-determination-cocaine An Aptamer-based Paper Microfluidic Device for the Colorimetric Determination of Cocaine | National... This article reports on the development of a method that uses paper microfluidics coupled with gold nanoparticles and two anticocaine aptamers to detect seized... https://publications-cnrc.canada.ca/eng/view/object/?id=c5414c9b-5302-4caa-a514-b2759c8ba8a1 Development of an anti-vascular cell adhesion protein-1 aptamer for molecular imaging and... Development of an anti-vascular cell adhesion protein-1 aptamer for molecular imaging and inflammation detection in transgenic mouse model of Alzheimer's... https://nij.ojp.gov/library/publications/label-free-aptamer-fluorophore-assembly-rapid-and-specific-detection-cocaine An Label-Free Aptamer-Fluorophore Assembly for Rapid and Specific Detection of Cocaine in Biofluids... This article reports a rapid and specific aptamer-based method for one-step cocaine detection with minimal reagent requirements. https://scholars.duke.edu/grant/285394 Scholars@Duke grant: Reducing prostate cancer aggressiveness via aptamer-mediated nuclear delivery... prostate cancer https://publikationen.uni-tuebingen.de/xmlui/handle/10900/36117?show=full Identification of an Aptamer Binding to Human Osteogenic-Induced Progenitor Cells identificationaptamerbinding https://www.mdpi.com/1420-3049/30/9/2012 Early-Stage Pancreatic Cancer Diagnosis: Serum Biomarkers and the Potential for Aptamer-Based... Pancreatic cancer has a high mortality rate, and both the incidence and mortality are continuing to increase in many countries globally. The poor prognosis of... https://www.mdpi.com/1424-8220/22/3/1281 A Simple Yet Effective Preanalytical Strategy Enabling the Application of Aptamer-Conjugated Gold... The misuse of antibiotics in the cattle sector can lead to milk contamination, with concomitant effects on the dairy industry and human health. Biosensors can... https://experts.mcmaster.ca/scholarly-works/2775073 Engineering a Ligase Binding DNA Aptamer into a... Learn about the scholarly work entitled Engineering a Ligase Binding DNA Aptamer into a... engineeringligasebindingdnaaptamer https://pure.psu.edu/en/publications/a-gapmer-aptamer-nanobiosensor-for-real-time-monitoring-of-transc/ A gapmer aptamer nanobiosensor for real-time monitoring of transcription and translation in single... https://www.news-medical.net/news/20090806/Reversible-cell-specific-drug-delivery-with-aptamer-functionalized-liposomes.aspx Reversible cell-specific drug delivery with aptamer-functionalized liposomes Jun 19, 2019 - For cancer drug developers, finding an agent that kills tumor cells is only part of the equation. The drug must also spare healthy cells, and - ideally - its... drug deliveryreversiblecellspecificaptamer https://nij.ojp.gov/library/publications/aptamer-integrated-multianalyte-detecting-paper-electrochemical-device Aptamer-Integrated Multianalyte-Detecting Paper Electrochemical Device | National Institute of... Using oligonucleotide-based aptamers as biorecognition elements, we here for the first time have developed a simple, inexpensive procedure for the fabrication... national instituteaptamerintegrateddetectingpaper https://portal.fis.tum.de/en/publications/fluorescence-activated-cell-sorting-for-aptamer-selex-with-cell-m/ Fluorescence-activated cell sorting for aptamer SELEX with cell mixtures - Technical University of... cell sorting https://research.utwente.nl/en/publications/aptamer-based-spatiotemporally-controlled-growth-factor-patternin/ Aptamer based spatiotemporally controlled growth factor patterning for tunable local microvascular... growth factoraptamerbasedcontrolled https://bwrc.berkeley.edu/publications/design-and-analysis-sample-and-hold-cmos-electrochemical-sensor-aptamer-based Design and Analysis of a Sample-and-Hold CMOS Electrochemical Sensor for Aptamer-Based Therapeutic... design and analysis https://pubs.rsc.org/en/content/articlelanding/2020/sc/d0sc03920a A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking... Rapid and accurate diagnosis of COVID-19 plays an essential role in the current epidemic prevention and control. Despite the promise of nucleic acid and... https://pure.psu.edu/en/projects/three-dimensional-one-step-aptamer-selection-in-the-non-fouling-m/ Three-dimensional One-step Aptamer Selection in the Non-fouling Macroporous Hydrogel - Penn State https://pubmed.ncbi.nlm.nih.gov/39779896/ Sialic acid aptamer and RNA in situ hybridization-mediated proximity ligation assay for spatial... Glycosylated RNAs (glycoRNAs) have recently emerged as a new class of molecules of substantial interest owing to their potential roles in cellular processes... https://scholars.duke.edu/publication/1638793 Scholars@Duke publication: An RNA aptamer exploits exosite-dependent allostery to achieve specific... https://necat.chem.cornell.edu/compact-stem-loop-dna-aptamer-targets-uracil-binding-pocket-sars-cov-2-nucleocapsid-rna-binding A compact stem-loop DNA aptamer targets a uracil-binding pocket in the SARS-CoV-2 nucleocapsid... https://scholars.cityu.edu.hk/en/publications/real-time-atp-monitoring-in-human-serum-by-a-nanofluidic-device-i/ REAL-TIME ATP MONITORING IN HUMAN SERUM BY A NANOFLUIDIC DEVICE INTEGRATED WITH AN APTAMER SENSOR -... https://dukespace.lib.duke.edu/items/04590f08-e790-4076-9ff7-bc51e3458bab Development of universal antidotes to control aptamer activity. With an ever increasing number of people taking numerous medications, the need to safely administer drugs and limit unintended side effects has never been... developmentuniversalantidotescontrolaptamer https://pubs.rsc.org/en/Content/ArticleLanding/2017/NJ/C7NJ01159H An ultrasensitive chemiluminescence aptasensor for indirect hemin detection based on aptamer... In this work, an ultrasensitive chemiluminescence (CL) aptasensor was prepared for indirect hemin detection based on hemin aptamer modified magnetic graphene... based onultrasensitivechemiluminescence https://cordis.europa.eu/project/id/707229 Aptamer nanostructures dual-targeted to the HER receptor family for cancer therapy | ADHERE |... The proposed research programme deals with the development of aptamer nanostructures for targeted cancer therapy. Immunotherapy encompasses a growing field of... https://experts.umn.edu/en/projects/rapid-poc-toxin-assay-using-aptamer-functionalized-magne/ Rapid POC Toxin Assay using Aptamer-Functionalized Magne - Experts@Minnesota rapid poctoxinassayusingaptamer https://pure.psu.edu/en/publications/aptamer-based-molecular-recognition-for-biosensor-development/ Aptamer-based molecular recognition for biosensor development - Penn State molecular recognitionaptamerbasedbiosensordevelopment https://pubmed.ncbi.nlm.nih.gov/38111313/ Aptamer Based SPREETA Sensor for the Detection of Porphyromonas gingivalis G-Protein for the https://scholars.duke.edu/publication/830341 Scholars@Duke publication: Identification and characterization of an agonistic aptamer against the... https://publications-cnrc.canada.ca/eng/view/object/?id=9cf619e9-ec28-4d2a-b640-51e6f28ce339 DAPTEV: deep aptamer evolutionary modelling for COVID-19 drug design - NRC Publications Archive -... DAPTEV: deep aptamer evolutionary modelling for COVID-19 drug design https://scholars.duke.edu/publication/1568629 Scholars@Duke publication: Aptamer-Small Molecule Conjugates As Potent and Reversible Surgical... small molecule https://digital.library.adelaide.edu.au/items/045c1a7f-ef03-46d5-a075-3624e1e3b10c Aptamer conjugated theragnostic multifunctional magnetic nanoparticles as a nanoplatform for... Pancreatic cancer is the fifth leading cause of cancer related deaths worldwide. Currently, finding an effective drug delivery strategy in pancreatic cancer... magnetic nanoparticlesaptamermultifunctional https://pubchem.ncbi.nlm.nih.gov/bioassay/488806 AID 488806 - RNA aptamer-based validation for inhibitors of GRK2 - PubChem BioAssay record AID 488806 submitted by NMMLSC: RNA aptamer-based validation for inhibitors of GRK2. aidrnaaptamerbased