Robuta

https://pmc.ncbi.nlm.nih.gov/articles/PMC19429/ Bcl-xL protects adult septal cholinergic neurons from axotomized cell death - PMC Bcl-xL suppresses apoptotic cell death induced by diverse stimuli in cell lines in vitro. To examine the mechanism by which axotomized cholinergic neurons die... bcl xlcholinergic neurons https://en.wikipedia.org/wiki/Bcl-xL Bcl-xL - Wikipedia bcl xlwikipedia https://www.ncbi.nlm.nih.gov/Structure/pdb/6UVC 6UVC: Crystal structure of BCL-XL bound to compound 8:... Bcl-2-like protein... crystal structurebcl xlboundcompound8 https://www.rcsb.org/structure/4EHR RCSB PDB - 4EHR: Crystal structure of Bcl-Xl complex with... Crystal structure of Bcl-Xl complex with... rcsb pdbcrystal structurebcl xlcomplex https://www.thermofisher.com/antibody/product/Bcl-XL-Antibody-Polyclonal/26967-1-AP Bcl-XL Polyclonal Antibody | Invitrogen (26967-1-AP) Detect Bcl-XL in WB, Flow, ICC/IF, IHC (P), IP. Reacts with Rabbit, Mouse, Chicken, Sheep. Cited in 60 publications. Catalog # 26967-1-AP bcl xlpolyclonal antibodyinvitrogen1ap https://www.ncbi.nlm.nih.gov/Structure/pdb/6UVG 6UVG: Crystal structure of BCL-XL bound to compound 13:... Bcl-2-like protein 1(R)-2-(3-([1,1'-Biphenyl]-4-carbonyl)-3-(4-methylbenzyl)ureido)-3-(((3R,5R,7R)-adamantan-1-ylmethyl)sulfonyl)propanoic... crystal structurebcl xlboundcompound13 https://www.rcsb.org/structure/4TUH RCSB PDB - 4TUH: Bcl-xL in complex with inhibitor (Compound 10) Bcl-xL in complex with inhibitor (Compound 10) rcsb pdbbcl xl https://pmc.ncbi.nlm.nih.gov/articles/PMC4470044/ Lipoic acid decreases Mcl-1, Bcl-xL and up regulates Bim on ovarian carcinoma cells leading to cell... Ovarian carcinoma is the leading cause of death from gynecological cancer because there is risk of chemoresistance. As previously demonstrated in our... https://pmc.ncbi.nlm.nih.gov/articles/PMC22498/ Bcl-XL interacts with Apaf-1 and inhibits Apaf-1-dependent caspase-9 activation - PMC Recent studies indicate that Caenorhabditis elegans CED-4 interacts with and promotes the activation of the death protease CED-3, and that this activation is... https://pmc.ncbi.nlm.nih.gov/articles/PMC6589348/ Lipid-Modulation of Membrane Insertion and Refolding of the Apoptotic Inhibitor Bcl-xL - PMC Bcl-xL is a member of the Bcl-2 family of apoptotic regulators, responsible for inhibiting the permeabilization of the mitochondrial outer membrane, and a... https://www.rcsb.org/structure/1BXL RCSB PDB - 1BXL: STRUCTURE OF BCL-XL/BAK PEPTIDE COMPLEX, NMR, MINIMIZED AVERAGE STRUCTURE STRUCTURE OF BCL-XL/BAK PEPTIDE COMPLEX, NMR, MINIMIZED AVERAGE STRUCTURE https://www.rcsb.org/structure/4A1U RCSB PDB - 4A1U: Crystal structure of alpha-beta-foldamer 2c in complex with Bcl-xL Crystal structure of alpha-beta-foldamer 2c in complex with Bcl-xL https://pmc.ncbi.nlm.nih.gov/articles/PMC8449356/ Lipids modulate the BH3-independent membrane targeting and activation of BAX and Bcl-xL - PMC Here, we characterize a mechanism that modulates the membrane targeting, refolding, and activation of the apoptotic regulators BAX and Bcl-xL in the absence of... https://www.rcsb.org/structure/3INQ RCSB PDB - 3INQ: Crystal structure of BCL-XL in complex with W1191542 Crystal structure of BCL-XL in complex with W1191542 rcsb pdbcrystal structure https://www.rcsb.org/structure/9AQZ RCSB PDB - 9AQZ: Crystal structure of Bcl-xL in complex with a small molecule inhibitor Crystal structure of Bcl-xL in complex with a small molecule inhibitor https://www.rcsb.org/structure/3QKD RCSB PDB - 3QKD: Crystal structure of Bcl-xL in complex with a Quinazoline sulfonamide inhibitor Crystal structure of Bcl-xL in complex with a Quinazoline sulfonamide inhibitor https://www.dana-farber.org/clinical-trials/25-076 A phase 1b study of BCL-XL degrader DT2216 in combination with weekly paclitaxel in recurrent... The purpose of this research study is determining the highest dose of the study drug DT2216 in combination with paclitaxel that can be safely and tolerably... https://www.rcsb.org/structure/2MEJ RCSB PDB - 2MEJ: Solution Structure of the Complex Between BCL-xL and the p53 Core Domain... Solution Structure of the Complex Between BCL-xL and the p53 Core Domain determined with PRE restraints https://www.rcsb.org/structure/6ZHC RCSB PDB - 6ZHC: PROTAC6 mediated complex of VHL:EloB:EloC and Bcl-xL PROTAC6 mediated complex of VHL:EloB:EloC and Bcl-xL https://www.ncbi.nlm.nih.gov/Structure/pdb/8VXM 8VXM: Human Bcl-2/Bcl-xL Chimera Fused to MBP in Complex with Inhibitor S55746 Maltose/maltodextrin-binding periplasmic protein fused to apoptosis regulator Bcl-2/Bcl-xL... https://www.wikidata.org/wiki/Q28249553 BH3 Domain of BAD Is Required for Heterodimerization with BCL-XL and Pro-apoptotic Activity -... scientific article published on September 26, 1997