bromodomain - Robuta Search

https://www.rcsb.org/structure/5EA1 RCSB PDB - 5EA1: Crystal Structure of SMARCA4 bromodomain in complex with MPD Crystal Structure of SMARCA4 bromodomain in complex with MPD rcsb pdb crystal structure https://www.rcsb.org/structure/5E7D RCSB PDB - 5E7D: Crystal Structure of the fifth bromodomain of human PB1 in complex with a... Crystal Structure of the fifth bromodomain of human PB1 in complex with a hydroxyphenyl ligand https://www.ncbi.nlm.nih.gov/Structure/pdb/5F1L 5F1L: Crystal structure of the bromodomain of BRD9 in complex with compound 9 Bromodomain-containing protein 95-[3,5-dimethoxy-4-[(3-oxidanylazetidin-1-yl)methyl]phenyl]-1,3-dimethyl-pyridin-2-one crystal structure of the https://www.rcsb.org/structure/7L9L RCSB PDB - 7L9L: Crystal structure of the second bromodomain (BD2) of human BRD3 bound to BI2536 Crystal structure of the second bromodomain (BD2) of human BRD3 bound to BI2536 https://www.ncbi.nlm.nih.gov/Structure/pdb/5C87 5C87: Crystal structure of the human BRPF1 bromodomain in complex with SEED2 PeregrinNITRATE IONisoquinolin-1(2H)-one crystal structure of the https://www.rcsb.org/structure/6HOV RCSB PDB - 6HOV: Crystal Structure of BRD4 first bromodomain in complex with ferulic acid Crystal Structure of BRD4 first bromodomain in complex with ferulic acid https://www.ncbi.nlm.nih.gov/Structure/pdb/5HEL 5HEL: Crystal structure of the N-terminus Y153H bromodomain mutant of human BRD2 Bromodomain-containing protein 21,2-ETHANEDIOL crystal structure of the n terminus https://www.ncbi.nlm.nih.gov/protein/5PDB_A Chain A, Bromodomain adjacent to zinc finger domain protein 2B - Protein - NCBI zinc finger domain chain bromodomain adjacent https://www.rcsb.org/structure/5IGN RCSB PDB - 5IGN: Crystal structure of human BRD9 bromodomain in complex with LP99 chemical probe Crystal structure of human BRD9 bromodomain in complex with LP99 chemical probe https://www.ncbi.nlm.nih.gov/Structure/pdb/7LB1 7LB1: Crystal structure of the tandem bromodomain (BD1, BD2) of human TAF1 bound to ZS1-585 Transcription initiation factor TFIID subunit... https://www.rcsb.org/structure/5F63 RCSB PDB - 5F63: Crystal structure of the first bromodomain of human BRD4 in complex with SG3-179 Crystal structure of the first bromodomain of human BRD4 in complex with SG3-179 https://www.news-medical.net/whitepaper/20251010/Using-BioPALS-to-study-the-BRPF1b-bromodomain.aspx Using BioPALS to study the BRPF1b bromodomain Oct 10, 2025 - Learn how BioPALS is applied to study the BRPF1b bromodomain. using study bromodomain https://www.ncbi.nlm.nih.gov/Structure/pdb/5D3S 5D3S: First bromodomain of BRD4 bound to inhibitor XD44 Bromodomain-containing protein 4(R,R)-2,3-BUTANEDIOL4-acetyl-3-ethyl-N-[4-fluoro-3-(morpholin-4-ylsulfonyl)phenyl]-5-methyl-1H-pyrrole-2-carboxamideDIMETHYL... first bromodomain brd4 bound inhibitor https://www.rcsb.org/structure/1X0J RCSB PDB - 1X0J: Crystal structure analysis of the N-terminal bromodomain of human Brd2 Crystal structure analysis of the N-terminal bromodomain of human Brd2 https://www.ncbi.nlm.nih.gov/protein/6JI5_A Chain A, Bromodomain-containing protein 4 - Protein - NCBI chain bromodomain containing protein 4 https://www.rcsb.org/structure/6S56 RCSB PDB - 6S56: Crystal structure of human ATAD2 bromodomain in complex with... Crystal structure of human ATAD2 bromodomain in complex with... rcsb pdb crystal structure https://www.ncbi.nlm.nih.gov/Structure/pdb/6ZB2 6ZB2: C-TERMINAL BROMODOMAIN OF HUMAN BRD2 WITH GSK549 Bromodomain-containing protein... c terminal bromodomain human brd2 https://www.rcsb.org/structure/5EP7 RCSB PDB - 5EP7: Crystal structure of the bromodomain of human CREBBP in complex with UN32 Crystal structure of the bromodomain of human CREBBP in complex with UN32 https://www.ncbi.nlm.nih.gov/Structure/pdb/3UVY 3UVY: Crystal Structure of the first bromodomain of human BRD4 in complex with a diacetylated... Bromodomain-containing protein 4Histone H4 https://www.ncbi.nlm.nih.gov/Structure/pdb/6Y7J 6Y7J: Structure of the BRD9 bromodomain and compound 15 Bromodomain-containing protein 91-[8-(2,5-dimethoxyphenyl)pyrrolo[1,2-a]pyrimidin-6-yl]ethanone of the structure brd9 bromodomain compound https://www.ncbi.nlm.nih.gov/Structure/pdb/5C89 5C89: Crystal structure of the human BRPF1 bromodomain in complex with 917 Peregrin1-ethyl-8-methoxy-5-methyl[1,2,4]triazolo[4,3-a]quinoline crystal structure of the https://www.ncbi.nlm.nih.gov/Structure/pdb/5R4V 5R4V: XChem fragment screen -- CRYSTAL STRUCTURE OF THE BROMODOMAIN OF THE HUMAN ATAD2 in complex... ATPase family AAA domain-containing protein 21,2-ETHANEDIOLSULFATE ION[4-(cyclopropanecarbonyl)piperazin-1-yl](furan-2-yl)methanone https://www.ncbi.nlm.nih.gov/Structure/pdb/6DDI 6DDI: Crystal Structure of the human BRD2 BD1 bromodomain in complex with a Tetrahydroquinoline... https://www.ncbi.nlm.nih.gov/Structure/pdb/6YQN 6YQN: Crystal structure of the first bromodomain of human BRD4 in complex with the dual inhibitor... Bromodomain-containing protein... https://www.rcsb.org/structure/5DKH RCSB PDB - 5DKH: Crystal structure of the bromodomain of human BRM (SMARCA2) in complex with a... Crystal structure of the bromodomain of human BRM (SMARCA2) in complex with a hydroxyphenyl propenone inhibitor 17 https://www.ncbi.nlm.nih.gov/Structure/pdb/5C4Q 5C4Q: Crystal Structure Analysis of bromodomain from Leishmania donovani complexed with bromosporine BromodomainBromosporine crystal structure https://www.rcsb.org/structure/5FE0 RCSB PDB - 5FE0: Crystal structure of human PCAF bromodomain in complex with acetyllysine Crystal structure of human PCAF bromodomain in complex with acetyllysine https://www.cancer.gov/research/participate/clinical-trials/intervention/bet-bromodomain-inhibitor-zen-3694?pn=1 Clinical Trials Using BET Bromodomain Inhibitor ZEN-3694 - NCI NCI supports clinical trials that test new and more effective ways to treat cancer. Find clinical trials studying bet bromodomain inhibitor zen-3694. clinical trials bromodomain inhibitor using bet zen https://www.ncbi.nlm.nih.gov/protein/5M3A_A Chain A, Bromodomain-containing protein 4 - Protein - NCBI chain bromodomain containing protein 4 https://www.rcsb.org/structure/4LR6 RCSB PDB - 4LR6: Structure of BRD4 bromodomain 1 with a 3-methyl-4-phenylisoxazol-5-amine fragment Structure of BRD4 bromodomain 1 with a 3-methyl-4-phenylisoxazol-5-amine fragment https://www.rcsb.org/structure/5AME RCSB PDB - 5AME: Crystal structure of the bromodomain of human surface epitope engineered BRD1A in... Crystal structure of the bromodomain of human surface epitope engineered BRD1A in complex with 3D Consortium fragment 4-acetyl- piperazin-2-one (SGC - Diamond... https://www.rcsb.org/structure/6ALC RCSB PDB - 6ALC: CREBBP bromodomain in complex with Cpd 4... CREBBP bromodomain in complex with Cpd 4 (1-(1-(cyclopropylmethyl)-3-(1H-indol-4-yl)-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl)ethan-1-one) rcsb pdb crebbp bromodomain complex cpd https://www.rcsb.org/structure/2YEL RCSB PDB - 2YEL: Crystal Structure of the First Bromodomain of Human Brd4 with the inhibitor... Crystal Structure of the First Bromodomain of Human Brd4 with the inhibitor GW841819X https://www.ncbi.nlm.nih.gov/Structure/pdb/5KTX 5KTX: CREBBP bromodomain in complex with Cpd59... CREB-binding... crebbp bromodomain complex https://www.ncbi.nlm.nih.gov/Structure/pdb/4Z1S 4Z1S: Crystal structure of the first bromodomain of human BRD4 with benzotriazolo-diazepine scaffold Bromodomain-containing protein 45-[(4S)-6-(4-chlorophenyl)-1,4-dimethyl-5,6-dihydro-4H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepin-8-yl]pyridin-2-amine https://www.ncbi.nlm.nih.gov/Structure/pdb/8IDH 8IDH: Bromodomain and Extra-terminal Domain (BET) BRD4 bromodomain extra terminal bet brd4 https://www.rcsb.org/structure/5M3A RCSB PDB - 5M3A: Crystal structure of BRD4 BROMODOMAIN 1 IN COMPLEX WITH LIGAND 2 Crystal structure of BRD4 BROMODOMAIN 1 IN COMPLEX WITH LIGAND 2 https://www.rcsb.org/structure/6P38 RCSB PDB - 6P38: Crystal Structure Analysis of TAF1 Bromodomain Crystal Structure Analysis of TAF1 Bromodomain rcsb pdb crystal structure analysis taf1 bromodomain https://www.ncbi.nlm.nih.gov/Structure/pdb/4XY9 4XY9: Crystal Structure of the first bromodomain of human BRD4 in complex with a 2-amine-9H-purine... Bromodomain-containing protein 41,2-ETHANEDIOL6-(5-bromo-2-methoxyphenyl)-9H-purin-2-amine https://www.ncbi.nlm.nih.gov/Structure/pdb/8FVK 8FVK: First bromodomain of BRD4 liganded with CCS-1477 Bromodomain-containing protein... first bromodomain brd4 ccs 1477 https://www.ncbi.nlm.nih.gov/gene/57261 Brd4 bromodomain containing 4 [Mus musculus (house mouse)] - Gene - NCBI mus musculus house mouse brd4 bromodomain containing https://www.ncbi.nlm.nih.gov/protein/5AME_A Chain A, BROMODOMAIN-CONTAINING PROTEIN 1 - Protein - NCBI chain bromodomain containing protein 1 https://www.rcsb.org/structure/4RVR RCSB PDB - 4RVR: Crystal Structure of the bromodomain of human BAZ2B in complex WITH GSK2801 Crystal Structure of the bromodomain of human BAZ2B in complex WITH GSK2801 https://www.rcsb.org/structure/5D3S RCSB PDB - 5D3S: First bromodomain of BRD4 bound to inhibitor XD44 First bromodomain of BRD4 bound to inhibitor XD44 rcsb pdb first bromodomain https://www.ncbi.nlm.nih.gov/Structure/pdb/5H85 5H85: Crystal structure of the bromodomain of human CREBBP in complex with UO37D crystal structure of the https://www.ncbi.nlm.nih.gov/Structure/pdb/4UIZ 4UIZ: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH... BROMODOMAIN-CONTAINING PROTEIN 41,2-ETHANEDIOL7-(3,4-dimethoxyphenyl)-5-methyl-2-(4-methylsulfonylpiperazin-1-yl)carbonyl-thieno[3,2-c]pyridin-4-one n terminal bromodomain human brd4 https://www.ncbi.nlm.nih.gov/Structure/pdb/5N17 5N17: First Bromodomain (BD1) from Candida albicans Bdf1 bound to a dibenzothiazepinone (compound 3) https://www.rcsb.org/structure/2L85 RCSB PDB - 2L85: Solution NMR structures of CBP bromodomain with small molecule of HBS Solution NMR structures of CBP bromodomain with small molecule of HBS https://www.ncbi.nlm.nih.gov/Structure/pdb/8FXO 8FXO: Bromodomain of CBP liganded with iCBP8 CREB-binding... bromodomain cbp https://www.ncbi.nlm.nih.gov/Structure/pdb/5ENH 5ENH: Crystal structure of the second bromodomain of Pleckstrin homology domain interacting protein... pleckstrin homology domain crystal structure of the https://www.ncbi.nlm.nih.gov/Structure/pdb/6KMB 6KMB: Crystal structure of Sth1 bromodomain Nuclear protein STH1/NPS1GLYCEROL crystal structure bromodomain https://www.rcsb.org/structure/5T35 RCSB PDB - 5T35: The PROTAC MZ1 in complex with the second bromodomain of Brd4 and... The PROTAC MZ1 in complex with the second bromodomain of Brd4 and pVHL:ElonginC:ElonginB https://www.rcsb.org/structure/4YAX RCSB PDB - 4YAX: Crystal structure of TRIM24 PHD-bromodomain complexed with... Crystal structure of TRIM24 PHD-bromodomain complexed with N-[6-(4-methoxyphenoxy)-1,3-dimethyl-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-5-yl]benzenesulfonamide... rcsb pdb crystal structure https://www.rcsb.org/structure/5F36 RCSB PDB - 5F36: Crystal structure of the bromodomain of human ATAD2 in complex with Compound A12 Crystal structure of the bromodomain of human ATAD2 in complex with Compound A12 https://www.ncbi.nlm.nih.gov/protein/5HLS_A Chain A, Bromodomain-containing protein 4 - Protein - NCBI chain bromodomain containing protein 4 https://www.ncbi.nlm.nih.gov/nuccore/NM_033656.4 Homo sapiens bromodomain and WD repeat domain containing 1 (BRWD1), tr - Nucleotide - NCBI https://www.rcsb.org/structure/2DAT RCSB PDB - 2DAT: Solution structure of the Bromodomain of human SWI/SNF related matrix associated... Solution structure of the Bromodomain of human SWI/SNF related matrix associated actin dependent regulator of cromatin subfamily A member 2 https://www.rcsb.org/structure/3LXJ RCSB PDB - 3LXJ: Crystal Structure of the Bromodomain of Human AAA domain containing 2B (ATAD2B) Crystal Structure of the Bromodomain of Human AAA domain containing 2B (ATAD2B) https://www.ncbi.nlm.nih.gov/Structure/pdb/4Z6I 4Z6I: Crystal structure of BRD9 bromodomain in complex with a substituted valerolactam quinolone... Bromodomain-containing protein 9tert-butyl [(2R,3S)-1-(1,4-dimethyl-2-oxo-1,2-dihydroquinolin-7-yl)-6-oxo-2-phenylpiperidin-3-yl]carbamate https://elifesciences.org/articles/21253/figures Figures and data in Replication Study: BET bromodomain inhibition as a therapeutic strategy to... Editors' Summary: This Replication Study has reproduced important parts of the original paper. https://www.rcsb.org/structure/5EIS RCSB PDB - 5EIS: FIRST DOMAIN OF HUMAN BROMODOMAIN BRD4 IN COMPLEX WITH INHIBITOR... FIRST DOMAIN OF HUMAN BROMODOMAIN BRD4 IN COMPLEX WITH INHIBITOR 3-(4-Chlorobenzyl)-7-ethyl-3,7-dihydropurine-2,6-dione https://www.ncbi.nlm.nih.gov/Structure/pdb/8B96 8B96: Crystal structure of the human BRD4-BD1 bromodomain in complex with the inhibitor CRCM5464 Bromodomain-containing protein 41,2-ETHANEDIOLDIMETHYL... https://www.rcsb.org/structure/4YC9 RCSB PDB - 4YC9: Crystal structure of TRIM24 PHD-bromodomain complexed with... Crystal structure of TRIM24 PHD-bromodomain complexed with... rcsb pdb crystal structure https://www.rcsb.org/structure/4PY6 RCSB PDB - 4PY6: Crystal Structure of bromodomain of PFA0510w from Plasmodium Falciparum Crystal Structure of bromodomain of PFA0510w from Plasmodium Falciparum rcsb pdb crystal structure https://www.ncbi.nlm.nih.gov/protein/5PCX_A Chain A, Bromodomain adjacent to zinc finger domain protein 2B - Protein - NCBI zinc finger domain chain bromodomain adjacent https://www.ncbi.nlm.nih.gov/Structure/pdb/5ENG 5ENG: Crystal structure of the bromodomain of human CREBBP in complex with UP39 crystal structure of the https://www.rcsb.org/structure/5L96 RCSB PDB - 5L96: Crystal Structure of BAZ2B bromodomain in complex with 3-amino-2-methylpyridine... Crystal Structure of BAZ2B bromodomain in complex with 3-amino-2-methylpyridine derivative 1 https://www.ncbi.nlm.nih.gov/protein/6U8I_A Chain A, Bromodomain-containing protein 4 - Protein - NCBI chain bromodomain containing protein 4 https://www.ncbi.nlm.nih.gov/protein/5PT1_A Chain A, Bromodomain-containing protein 1 - Protein - NCBI chain bromodomain containing protein 1 https://www.ncbi.nlm.nih.gov/Structure/pdb/5HFQ 5HFQ: Crystal structure of the second bromodomain Q443H mutant of human BRD2 Bromodomain-containing protein 2 crystal structure of the https://www.ncbi.nlm.nih.gov/protein/6V14_A Chain A, Bromodomain-containing protein 9 - Protein - NCBI chain bromodomain containing protein 9 https://healthandwellnesssource.org/ BET-bromodomain inhibition research bet bromodomain inhibition research https://www.rcsb.org/structure/5FFV RCSB PDB - 5FFV: Crystal structure of the bromodomain of human BRPF1 in complex with H3K14ac... Crystal structure of the bromodomain of human BRPF1 in complex with H3K14ac histone peptide https://www.ncbi.nlm.nih.gov/Structure/pdb/5EIC 5EIC: Crystal structure of the bromodomain of human CREBBP in complex with AYC CREB-binding protein1,2-ETHANEDIOL crystal structure of the https://www.rcsb.org/structure/6V14 RCSB PDB - 6V14: Crystal structure of the bromodomain of human BRD9 bound to TP472 Crystal structure of the bromodomain of human BRD9 bound to TP472