Robuta

Pseudomonas aeruginosa RmlA in complex with allosteric inhibitor

Programmed cell death 1 ligand 1~{N}-[[1-[(~{E})-2-(2-methyl-3-phenyl-phenyl)ethenyl]-1,2,3,4-tetrazol-5-yl]methyl]ethanamine

Tyrosine-protein kinase JAK2N~3~-phenyl-1-[6-(phenylamino)pyrimidin-4-yl]-1H-1,2,4-triazole-3,5-diamine

Nov 13, 2025 - Managing checkpoint inhibitor pneumonitis can be complex, so a multidisciplinary approach to care is key.

Gliomas are the second most common primary brain tumors in adults. They are treated with combination therapies, including surgery, radiotherapy, and...

Dual specificity protein kinase...

In clinical trials, adjuvant treatment with entacapone appeared to be an effective and well-tolerated therapeutic strategy in patients with Parkinson's disease...

Stop Grow works in inhibiting the growth of unwanted hair and it works for both men and women. It is a natural hair growth inhibitor and 100% safe to use.

Src family kinase Hck with bound inhibitor A-770041

A DNA polymerase inhibitor that interferes with the activity of reverse transcriptase, EC 2.7.7.49, a viral DNA polymerase enzyme that retroviruses need in...

YOYO EFFECT INHIBITOR YOYO EFFECT INHIBITORYOYO EFFECT INHIBITORYOYO EFFECT INHIBITORYOYO EFFECT INHIBITORYOYO EFFECT INHIBITORYOYO EFFECT INHIBITORYOYO...

EPD for GCP Applied Technologies Corrosion Inhibitor

Calmodulin2-{[(R)-{[(2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl]oxy}(hydroxy)phosphoryl]oxy}-N,N,N-trimethylethanaminiumCALCIUM ION

Crystal structure of human GAC in complex with inhibitor UPGL00012

Solution Structure of the complex between poxvirus-encoded CC chemokine inhibitor vCCI and human MIP-1beta, ensemble structure

Proteasome Inhibitor II The Proteasome Inhibitor II controls the biological activity of Proteasome. This small molecule/inhibitor is primarily used for...

We have produced a number of astrocytic cell lines, some of which promote abundant neurite outgrowth, some of which are poor promoters of neurite outgrowth....

DPP-4 inhibitor can improve 5-FU induced AM and, therefore, has potential as an alternative treatment for chemotherapy-induced AM.

Factor VIIa (Heavy Chain)Factor VIIa (Light...

Papain-like protease nsp35-[2-(dimethylamino)ethoxy]-2-methyl-N-{(1R)-1-[(3P,5M)-3-(1-methyl-1H-pyrazol-4-yl)-5-(1,3-thiazol-5-yl)phenyl]ethyl}benzamideACETATE...

Proteasome subunit alpha type-1Proteasome subunit alpha type-2Proteasome subunit alpha type-3Proteasome subunit alpha type-4Proteasome subunit alpha...

Pectin methylesterase inhibitors (PMEIs) modulate the status of pectin methylesterification by inhibiting the activity of pectin methylesterase (PME). Recen...

X-RAY STRUCTURE OF PRMT6 IN COMPLEX WITH indazole type inhibitor

Angiogenesis, the sprouting of new blood vessels from pre-existing ones, is an essential physiological process in development, yet also plays a major role in...

Crystal structure of CMET in complex with novel inhibitor

Mitogen-activated protein kinase 73-amino-5-[(4-chlorophenyl)amino]-N-[(1S)-1-phenylethyl]-1H-1,2,4-triazole-1-carboxamideGLYCEROL

Researchers at the University of Cincinnati (UC) College of Medicine are part of an international team that has identified how the inactive or latent form of...

Tumors with mutant RAS are often dependent on extracellular signal-regulated kinase (ERK) signaling for growth; however, MEK inhibitors have only marginal...

Crystal structure of PDE4D2 in complex with inhibitor LEO39652

Polyketide synthase Pks13 (Termination polyketide synthase)ethyl 5-hydroxy-4-(morpholin-4-ylmethyl)-2-phenyl-1-benzofuran-3-carboxylate

Cathepsin...

5 Simple Statements About LY3372689 OGA inhibitor Explained

Factor XIa (Light Chain)1,2-ETHANEDIOLMETHYL...

Plasmodium falciparum M1 aminopeptidase bound to selective inhibitor MIPS2673

3C-like...

HUMAN CYCLIN DEPENDENT KINASE 2 COMPLEXED WITH THE CDK4 INHIBITOR

Carbonic anhydrase 121,2-ETHANEDIOL3-(benzylamino)-2,5,6-trifluoro-4-[(2-phenylethyl)sulfonyl]benzenesulfonamideZINC ION

GROUP 10 SECRETORY PHOSPHOLIPASE A24-BENZYLBENZAMIDECALCIUM IONDI(HYDROXYETHYL)ETHERDIMETHYL SULFOXIDE

Structure of Pi3K gamma with a potent inhibitor: GSK2126458

GSK3b in complex with inhibitor

Water Treatment Scale Corrosion Inhibitor CAS 2809-21-4 HEDP 60%, find complete details about Water Treatment Scale Corrosion Inhibitor CAS 2809-21-4 HEDP 60%,...

Histone-lysine N-methyltransferase, H3 lysine-79 specific5'-deoxy-5'-[(3-{[(4-methylphenyl)carbamoyl]amino}propyl)(propan-2-yl)amino]adenosine

Crystal structure of human Galectin-3 in complex with small molecule inhibitor

Immunocheckpoint inhibitor (ICI) therapy has provided significant clinical improvements in the treatment of several malignancies. The purpose of this report is...

In recent years, inhibition of the interaction between the bromodomain and extra-terminal domain (BET) family of chromatin adaptors and acetyl-lysine residues...

NCI's Dictionary of Cancer Terms provides easy-to-understand definitions for words and phrases related to cancer and medicine.

The identification of the novel, selective, orally bioavailable Sortilin inhibitor AF38469 is described. Structure-activity relationships and syntheses are...

EndothiapepsinDI(HYDROXYETHYL)ETHERDIMETHYL SULFOXIDEN-benzyl-4-phenyl-2-[(N-phenyl-beta-alanyl)amino]thiophene-3-carboxamide

Trypsin, cationic(1R,3AS,4R,8AS,8BR)-4-(2-BENZO[1,3]DIOXOL-5-YL-1-CYCLOPROPYL-3-OXO-DECAHYDRO-PYRROLO[3,4-A]PYRROLIZIN-4-YL)-BENZAMIDINECALCIUM ION

Nura Bio, Inc. (Nura Bio), a biopharmaceutical company developing neuroprotective, small molecule therapies for the treatment of debilitating neurological...

Small-cell lung cancer (SCLC) accounts for nearly 15% of lung cancer cases and exhibits aggressive clinical behavior characterized by rapid growth and...

Structure of PYCR1 complexed with the allosteric inhibitor 1-benzyl-1H-1,3-benzodiazole-2-sulfonic acid

suitable for installation on cold water lines for the prevention of limescale formation.

China's first oral anti-COVID-19 pill with the SARS-CoV-2 3CL protease as the drug target hit the market on Sunday at a price of 750 yuan ($107.84) per packet,...

Volvo Support for V40 Gear selector inhibitor | There are two different types of gear selector inhibitor - mechanical and automatic.

Cyclin-dependent kinase 2(3R,4R)-4-[[[7-[(phenylmethyl)amino]-3-propan-2-yl-pyrazolo[1,5-a]pyrimidin-5-yl]amino]methyl]piperidin-3-olACETATE ION

The meaning of REVERSE TRANSCRIPTASE INHIBITOR is an agent that inhibits the activity of a reverse transcriptase; especially : a drug (as AZT) that acts by...

Endothiapepsin1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANEACETATE...

Our findings highlight that HJC0152 is a promising therapeutic agent for GC.

Staphylococcal Complement Inhibitor (SCIN) in complex with Human Complement Component C3b

Explore resources and support for families living with hemophilia inhibitors. Learn about educational events, publications, webinars, and more.

Histone deacetylase 25-{(1S)-7,7-dihydroxy-1-[(1-methylazetidine-3-carbonyl)amino]nonyl}-2-phenyl-1H-imidazole-4-carboxamideCALCIUM...

Dihydroorotate dehydrogenase (quinone), mitochondrialFLAVIN MONONUCLEOTIDEOROTIC ACIDethyl...

Prospective predictions of drug-resistant protein mutants could improve the design of therapeutics less prone to resistance. Here, we describe RESISTOR, an...

Immune checkpoint inhibitors (ICIs) are a new type of antitumor drug which can achieve antitumor goals by blocking the binding of immune checkpoints to their...

CATIONIC TRYPSIN1-[3-(aminomethyl)phenyl]-n-[3-fluoro-2'-(methylsulfonyl)biphenyl-4-yl]-3-(trifluoromethyl)-1h-pyrazole-5-carboxamideCalcium Ion

Crystal structure of PIM1 in complex with a Pyrrolo(1,2-a)Pyrazinone inhibitor

Regulatory protein BlaR1[1-[[2,4-bis(trifluoromethyl)phenyl]methyl]benzimidazol-2-yl]sulfanylmethyl-$l^{3}-oxidanyl-bis(oxidanyl)boron

Endoplasmin9-(pent-4-yn-1-yl)-8-[(2,4,6-trimethylphenyl)sulfanyl]-9H-purin-6-amineGLYCEROLMAGNESIUM IONSULFATE ION

Tankyrase-2ZINC ION~{N}-[3-[5-(5-ethoxypyridin-2-yl)-4-phenyl-1,2,4-triazol-3-yl]cyclobutyl]-1,5-naphthyridine-4-carboxamide

ephB4 kinase domain inhibitor complex

3C PROTEASEETHYL (4R)-4-[(TERT-BUTOXYCARBONYL)AMINO]-5-[(3S)-2-OXOPYRROLIDIN-3-YL]PENTANOATE

Evidence-based recommendations on ertugliflozin (Steglatro) with metformin and a dipeptidyl peptidase-4 inhibitor for type 2 diabetes in adults

Cyclophilin A single mutant D66A in complex with an inhibitor.

Background: Cyclin-dependent kinases (CDKs) regulate mammalian cell cycle progression and RNA transcription. Based on the structural analysis of previously...

Upadacitinib demonstrated sustained efficacy across musculoskeletal and skin domains in PsA patients with prior inadequate response to TNF inhibitors, with a...

Cyclin-dependent kinase 21,2-ETHANEDIOL2-(4,6-diamino-1,3,5-triazin-2-yl)phenolPHOSPHATE ION

Bromodomain-containing protein 41,2-ETHANEDIOL

Crystal Structure of a Pyrazolopyrimidine Inhibitor Bound to PI3 Kinase Gamma

BRAF Inhibitor Resistance Confers Increased Sensitivity to Mitotic Inhibitors. by Sean A Misek, Bardees M Foda, Thomas S Dexheimer, Maisah Akram, Susan E...

Methane combustion in a continuously stirred flow tank reactor (CSTR) in the presence and absence of chemical inhibitors such as CF3I, CF3Br, CF3H, and a chemic