Robuta

https://pmc.ncbi.nlm.nih.gov/articles/PMC11968822/ Genome-wide CRISPR screen identifies BUB1 kinase as a druggable vulnerability in malignant pleural... Malignant pleural mesothelioma (MPM) is a rare yet highly aggressive malignancy with a severe prognosis. Compounded by the lack of effective treatment... https://elifesciences.org/articles/05269/peer-reviews Peer review in A molecular basis for the differential roles of Bub1 and BubR1 in the spindle... The mechanism behind the recruitment of the spindle assembly checkpoint protein BubR1 to the kinetochore illustrates how gene duplication and... https://elifesciences.org/articles/05269/figures Figures and data in A molecular basis for the differential roles of Bub1 and BubR1 in the spindle... The mechanism behind the recruitment of the spindle assembly checkpoint protein BubR1 to the kinetochore illustrates how gene duplication and... https://www.ncbi.nlm.nih.gov/protein/5DMZ_A Chain A, Mitotic checkpoint serine/threonine-protein kinase BUB1 - Protein - NCBI mitotic checkpointserine threonineprotein kinasechainbub1 https://elifesciences.org/articles/12187 Probing the catalytic functions of Bub1 kinase using the small molecule inhibitors BAY-320 and... Chemical inhibition of Bub1 shows that the catalytic activity is not required for normal mitotic progression, but it makes chromosome segregation and cell...