https://www.rcsb.org/structure/3EQD
X-ray structure of the human mitogen-activated protein kinase kinase 1 (MEK1) in a binary complex with ATP-GS and MG2P
x rayrcsbpdbstructurehuman
https://www.ncbi.nlm.nih.gov/Structure/pdb/5AX9
TRAF2 and NCK-interacting protein kinase4-methoxy-3-[2-[(3-methoxy-4-morpholin-4-yl-phenyl)amino]pyridin-4-yl]benzenecarbonitrileSULFATE ION
crystal structurekinasedomainhuman
https://elifesciences.org/articles/94720
Why does protein kinase A respond to purine nucleosides in certain pathogens, but not to the cyclic nucleotides that activate this kinase in most other...
protein kinase aprobingligandselectivitypathogens
https://pubmed.ncbi.nlm.nih.gov/29317503/
The gut microbiome contributes to inflammatory bowel disease (IBD), in which bacteria can be present within the epithelium. Epithelial barrier function is...
er stressprotein kinasemobilizationdeathassociated
https://www.ncbi.nlm.nih.gov/Structure/pdb/3UZS
Beta-adrenergic receptor kinase 1C13.28 RNA AptamerGuanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2Guanine nucleotide-binding protein...
structurernaaptamerbound
https://pubmed.ncbi.nlm.nih.gov/30770398/
The interferon-inducible protein kinase R (PKR) is a key component of host innate immunity that restricts viral replication and propagation. As one of the four...
the searchpkrcodedifferentialregulation
https://pubmed.ncbi.nlm.nih.gov/30611608/
Since publication of the crystal structure of protein kinase (PK)A three decades ago, a structural portrait of the conserved kinase core has been drawn. The...
disordered proteinkinaseregionsregulationdomain
https://www.thermofisher.com/antibody/primary/panther/positive%20regulation%20of%20cyclin-dependent%20protein%20serine/threonine%20kinase%20activity%20involved%20in%20G2/M%20transition%20of%20mitotic%20cell%20cycle
Antibodies for proteins involved in positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic...
positive regulationcyclindependentproteinserine
https://www.ncbi.nlm.nih.gov/Structure/pdb/2GFC
cAMP-dependent protein kinase inhibitor alphacAMP-dependent protein kinase, alpha-catalytic subunitN-OCTANE
protein kinasecampdependentpkacatalytic
https://pubmed.ncbi.nlm.nih.gov/16177793/?dopt=Abstract
Hormones mobilize intracellular second messengers and initiate signalling cascades involving protein kinases and phosphatases, which are often spatially...
protein kinase abeta adrenergicinsulinsignalling
https://pubmed.ncbi.nlm.nih.gov/22509822/
Hypoxia activates AMPK-dependent and -independent pathways in airway epithelial cells. Importantly, these pathways differentially regulate apical Na(+)...
protein kinaseampactivateddependentpathways
https://www.frontiersin.org/journals/cell-and-developmental-biology/articles/10.3389/fcell.2024.1469751/full
IntroductionIron is crucial for brain function, but excessive iron is neurotoxic. Abnormally high brain iron accumulation is one of the pathogenic factors in...
protein kinasefrontierslosscalciumcalmodulin
https://www.sigmaaldrich.com/US/en/tech-docs/paper/1255152
Activation of phosphoinositide/protein kinase C pathway in rat brain tissue by pyrethroids. by E Enan, F Matsumura. Biochemical pharmacology. Read more related...
protein kinase cactivationphosphoinositidepathwayrat
https://www.frontiersin.org/journals/allergy/articles/10.3389/falgy.2021.656886/full
G protein-coupled receptor kinase 2 (GRK2) is an adapter protein that modulates G protein-coupled receptors (GPCRs) signaling. It also regulates the function...
g proteinfrontierscoupledreceptorkinase
https://pubmed.ncbi.nlm.nih.gov/18357561/
Signaling by cAMP-dependent protein kinase (PKA) plays an important role in the regulation of mammalian sperm motility. However, it has not been determined how...
bicarbonateinducedphosphorylationproteinmouse
https://www.ncbi.nlm.nih.gov/Structure/pdb/3NDM
Rho-Associated Protein Kinase (ROCK1)(3S,4R)-N-(7-chloro-1-oxo-1,4-dihydroisoquinolin-6-yl)-4-(4-chlorophenyl)pyrrolidine-3-carboxamide
crystal structureprotein kinaserhoassociated
https://www.ncbi.nlm.nih.gov/Structure/pdb/3IDC
cAMP-dependent protein kinase catalytic subunit alphacAMP-dependent protein kinase type II-beta regulatory subunitMANGANESE (II) IONPHOSPHOAMINOPHOSPHONIC...
crystal structureriibholoenzyme
https://www.ncbi.nlm.nih.gov/Structure/pdb/3PVB
cAMP-dependent protein kinase catalytic subunit alphacAMP-dependent protein kinase type I-alpha regulatory subunitGLYCEROLMANGANESE (II)...
crystal structureriaholoenzyme
https://pubmed.ncbi.nlm.nih.gov/16699172/
Controlling aberrant kinase-mediated cellular signaling is a major strategy in cancer therapy; successful protein kinase inhibitors such as Tarceva and Gleevec...
protein kinase astructural analysismutantsrho
https://pubmed.ncbi.nlm.nih.gov/21658591/
High-frequency stimulation leads to a transient increase in the amplitude of evoked synaptic transmission that is known as posttetanic potentiation (PTP). Here...
protein kinase ccalciumdependentisoformsmediate
https://elifesciences.org/articles/88210/figures
Understanding protein kinase regulation by activation loop autophosphorylation depends on a critical assessment of experimental design, execution, and...
in aprotein kinasefiguresdatacritical
https://pubmed.ncbi.nlm.nih.gov/36340039/
Stress-activated mitogen-activated protein kinase kinase 7 (MKK7) is a member of the dual-specificity mitogen-activated protein kinase family. In the human...
mitogen activated proteinkinaseinflammatorycancer