https://elifesciences.org/reviewed-preprints/101719/figures
Decreased Astrocytic CCL5 by MiR-324-5p Ameliorates Ischemic Stroke Injury via CCR5/ERK/CREB Pathway
https://elifesciences.org/articles/20985
CCR5 is a suppressor for cortical plasticity and hippocampal learning and memory | eLife
Repression of the G protein-coupled chemokine receptor CCR5 enhances MAPK/CREB signaling, long-term potentiation, somatosensory cortical plasticity, and...
is acortical plasticity
https://elifesciences.org/articles/44360/figures
Figures and data in Transcriptional down-regulation of ccr5 in a subset of HIV+ controllers and...
A subset of EC/VCs have CD4+T cells with resistance specific to R5-tropic HIV infection associated with transcriptional down-regulation of ccr5, a phenotype...
https://www.rcsb.org/structure/6AKX
RCSB PDB - 6AKX: The Crystal structure of Human Chemokine Receptor CCR5 in complex with compound 21
The Crystal structure of Human Chemokine Receptor CCR5 in complex with compound 21
https://www.omicsonline.org/peer-reviewed/t-cell-subpopulations-ccr5-and-cxcr4-in-discordant-couples-when-compared-with-concordant-and-healthy-control-subjectsp-87412.html
T Cell Subpopulations, CCR5 and CXCR4 in Discordant Couples when Compared with Concordant and...
T Cell Subpopulations, CCR5 and CXCR4 in Discordant Couples when Compared with Concordant and Healthy Control Subjects Abstract.
https://wellcomecollection.org/works/pr9rhkbp
DNA sequence of CCR5 Delta 32 gene mutation | Wellcome Collection
Sequence of the gene CCR5 Delta 32 in acrylic paint on polyester taffeta. The CCR5 gene produces the CCR5 receptor protein which normally inserts into the cell...
ccr5 delta 32dna sequencegene mutationwellcomecollection
https://www.preprints.org/manuscript/202311.0832
Control of CCR5 Cell Surface Targeting by the PRAF2 Gatekeeper[v1] | Preprints.org
The cell surface targeting of neo-synthesized G protein coupled receptors (GPCRs) involves recruitment of receptor into COPII vesicles budding at Endoplasmic...
https://pmc.ncbi.nlm.nih.gov/articles/PMC7654230/
CCR5 inhibition in critical COVID-19 patients decreases inflammatory cytokines, increases CD8...
Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is now a global pandemic. Emerging results indicate a dysregulated immune response....
covid 19
https://pmc.ncbi.nlm.nih.gov/articles/PMC7755305/
The G Protein Coupled Receptor CCR5 in Cancer - PMC
The G coupled protein receptor C-C chemokine receptor type 5 (CCR5) has the unusual characteristic in humans of being a developmentally non-essential gene that...
g protein coupled receptorccr5cancerpmc
https://www.rcsb.org/structure/2RRS
RCSB PDB - 2RRS: NMR Structure of LC4 transmembrane segment of CCR5
NMR Structure of LC4 transmembrane segment of CCR5
rcsb pdbtransmembrane segmentnmrstructurelc4
https://www.frontiersin.org/journals/genome-editing/articles/10.3389/fgeed.2022.1031275/full
Frontiers | Whole genome sequencing of CCR5 CRISPR-Cas9-edited Mauritian cynomolgus macaque...
Genome editing by CRISPR-Cas9 approaches offers promise for introducing or correcting disease-associated mutations for research and clinical applications. No...
whole genome sequencing
https://elifesciences.org/reviewed-preprints/101719v1
Decreased Astrocytic CCL5 by MiR-324-5p Ameliorates Ischemic Stroke Injury via CCR5/ERK/CREB Pathway
https://www.mdpi.com/1999-4915/17/4/465
Promoter Methylation of HIV Coreceptor-Related Genes CCR5 and CXCR4: Original Research
The persistence of human immunodeficiency virus (HIV) within viral reservoirs poses significant challenges to eradication efforts. Epigenetic alterations,...
promoter methylation
https://pmc.ncbi.nlm.nih.gov/articles/PMC109434/
CXCR-4 Is Expressed by Primary Macrophages and Supports CCR5-Independent Infection by Dual-Tropic...
Primary macrophages are infected by macrophage (M)-tropic but not T-cell line (T)-tropic human immunodeficiency virus type 1 (HIV-1) strains, and CCR5 and...
https://www.ebi.ac.uk/chembl/explore/document/CHEMBL1949642
Document: Balancing hERG affinity and absorption in the discovery of AZD5672, an orally active CCR5...
Report card for Document Balancing hERG affinity and absorption in the discovery of AZD5672, an orally active CCR5 antagonist for the treatment of rheumatoid...
https://www.ebi.ac.uk/chembl/explore/document/CHEMBL1144903
Document: Generation of predictive pharmacophore models for CCR5 antagonists: study with...
Report card for Document Generation of predictive pharmacophore models for CCR5 antagonists: study with piperidine- and piperazine-based compounds as a new...
document generationpredictivepharmacophore
https://www.jci.org/articles/view/181576
JCI - CCR5-edited CD4+ T cells augment HIV-specific immunity to enable post-rebound control of HIV...
https://www.jci.org/articles/view/37444
JCI - CCR1 and CCR5 promote hepatic fibrosis in mice
hepatic fibrosisjciccr1ccr5promote
https://pmc.ncbi.nlm.nih.gov/articles/PMC16249/
HIV-1 infection through the CCR5 receptor is blocked by receptor dimerization - PMC
The identification of the chemokine receptors as receptors for HIV-1 has boosted interest in these molecules, raising expectations for the development of new...
hiv 1 infectionthrough theccr5 receptor
https://www.mdpi.com/1999-4915/12/2/241
Identification of HIV-1 Envelope Mutations that Enhance Entry Using Macaque CD4 and CCR5
Although Rhesus macaques are an important animal model for HIV-1 vaccine development research, most transmitted HIV-1 strains replicate poorly in macaque...