https://pmc.ncbi.nlm.nih.gov/articles/PMC11607829/
CD22 blockade exacerbates neuroinflammation in Neuromyelitis optica spectrum disorder - PMC
Neuromyelitis optica spectrum disorder (NMOSD) is an autoantibody-triggered central nervous system (CNS) demyelinating disease that primarily affects the...
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https://pmc.ncbi.nlm.nih.gov/articles/PMC8363505/
CAR T cells with dual targeting of CD19 and CD22 in adult patients with recurrent or refractory B...
Despite impressive progress, more than 50% of patients treated with CD19-targeting chimeric antigen receptor T cells (CAR19) experience progressive disease....
https://www.cancerresearchuk.org/about-cancer/find-a-clinical-trial/a-trial-of-cd19-and-cd22-car-t-cells-to-treat-blood-cancers-in-children-and-young-people-carpall
A trial of CD19 and CD22 CAR T-cells to treat blood cancers in children and young people (CARPALL)
This trial was for children and young people with a leukaemia or lymphoma that had either come back or was likely to come back after treatment.
https://pmc.ncbi.nlm.nih.gov/articles/PMC8516648/
CAR T cells with dual targeting of CD19 and CD22 in pediatric and young adult patients with...
Chimeric antigen receptor (CAR) T cells targeting CD19 or CD22 have shown remarkable activity in B cell acute lymphoblastic leukemia (B-ALL). The major cause...
https://www.cancer.gov/research/participate/clinical-trials/intervention/anti-cd19-cd20-cd22-car-t-cells?pn=1
Clinical Trials Using Anti-CD19/CD20/CD22 CAR T-Cells - NCI
NCI supports clinical trials that test new and more effective ways to treat cancer. Find clinical trials studying anti-cd19/cd20/cd22 car t-cells.
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https://www.cancer.gov/research/participate/clinical-trials/intervention/autologous-anti-cd19-cd20-cd22-car-t-cells
Clinical Trials Using Autologous Anti-CD19/CD20/CD22 CAR T-cells - NCI
NCI supports clinical trials that test new and more effective ways to treat cancer. Find clinical trials studying autologous anti-cd19/cd20/cd22 car t-cells.
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https://www.cancer.gov/publications/dictionaries/cancer-drug/def/anti-cd22-car-t-cells-preparation
Definition of anti-CD22 CAR T cells preparation - NCI Drug Dictionary - NCI
Find technical definitions and synonyms by letter for drugs/agents used to treat patients with cancer or conditions related to cancer. Each entry includes...
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https://pmc.ncbi.nlm.nih.gov/articles/PMC8821938/
A novel and efficient tandem CD19- and CD22-directed CAR for B cell ALL - PMC
CD19-directed chimeric antigen receptor (CAR) T cells have yielded impressive response rates in refractory/relapse B cell acute lymphoblastic leukemia (B-ALL);...
https://pmc.ncbi.nlm.nih.gov/articles/PMC7126394/
Bispecific CAR-T cells targeting both CD19 and CD22 for therapy of adults with relapsed or...
Despite the impressive complete remission (CR) induced by CD19 CAR-T cell therapy in B-ALL, the high rate of complete responses is sometimes limited by the...
https://www.cancer.gov/research/participate/clinical-trials-search/v?id=NCT02315612&r=1
Anti-CD22 Chimeric Receptor T Cells in Pediatric and Young Adults With Recurrent or Refractory...
Anti-CD22 Chimeric Receptor T Cells in Pediatric and Young Adults With Recurrent or Refractory CD22-expressing B Cell Malignancies
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https://www.mayo.edu/research/clinical-trials/cls-20416407?&p=1
Inotuzumab Ozogamicin In Treating Younger Patients With Relapsed Or Refractory CD22 Positive B...