Robuta

https://www.ncbi.nlm.nih.gov/Structure/pdb/8VRT 8VRT: The structure of LSD1-CoREST-HDAC1 in complex with KBTBD4R313PRR mutant Histone deacetylase 1Kelch repeat and BTB domain-containing protein 4REST corepressor 1INOSITOL HEXAKISPHOSPHATEZINC ION the structure https://www.rcsb.org/structure/6KGN RCSB PDB - 6KGN: LSD1-CoREST-S2116 N5 adduct model LSD1-CoREST-S2116 N5 adduct model rcsb pdb lsd1 corest n5 adduct https://www.jci.org/articles/view/131375/pdf JCI - Inhibiting the coregulator CoREST impairs Foxp3+ Treg function and promotes antitumor immunity https://pmc.ncbi.nlm.nih.gov/articles/PMC22303/ CoREST: A functional corepressor required for regulation of neural-specific gene expression - PMC Several genes encoding proteins critical to the neuronal phenotype, such as the brain type II sodium channel gene, are expressed to high levels only in...