https://www.frontiersin.org/journals/physiology/articles/10.3389/fphys.2023.1134339/full
Cullin-RING ubiquitin ligases (CRL) regulate numerous biological processes in the heart and have been implicated in regulating cardiac hypertrophy. This stud...
ubiquitin ligasesfrontiersidentificationhypertrophymodulating
https://www.ncbi.nlm.nih.gov/Structure/cdd/smart00884
smart00884 (PSSM ID: 214883): Conserved Protein Domain Family Cullin_Nedd8, This is the neddylation site of cullin proteins which are a family of structurally...
conserved proteincdddomainfamilycullin
https://www.rcsb.org/structure/8Q7R
Ubiquitin ligation to substrate by a cullin-RING E3 ligase & Cdc34: NEDD8-CUL2-RBX1-ELOB/C-FEM1C with trapped UBE2R2~donor UB-Sil1 peptide
rcsbpdbubiquitinligationsubstrate
https://www.ncbi.nlm.nih.gov/Structure/cdd/pfam03556
pfam03556 (PSSM ID: 515662): Conserved Protein Domain Family Cullin_binding, This domain binds to cullins and to Rbx-1, components of an E3 ubiquitin ligase...
conserved proteincdddomainfamilycullin
https://pubmed.ncbi.nlm.nih.gov/21624359/
The Cullin-RING ubiquitin-ligase CRL4 controls cell cycle and DNA damage checkpoint response and ensures genomic integrity. Inactivation of the Cul4 component...
ubiquitin ligasecullinmeioticprogression
https://www.ncbi.nlm.nih.gov/Structure/pdb/8R5H
Bromodomain-containing protein 4Cullin-2E3 ubiquitin-protein ligase RBX1, N-terminally processedElongin-BElongin-CUbiquitinUbiquitin-conjugating enzyme E2...
ubiquitinligationcullinring