ubiquitin - Robuta Search

https://pubmed.ncbi.nlm.nih.gov/31722399/

Transcription-coupled nucleotide excision repair is coordinated by ubiquitin and SUMO in response...

Cockayne Syndrome (CS) is a severe neurodegenerative and premature aging autosomal-recessive disease, caused by inherited defects in the CSA and CSB genes,...

nucleotide excision repair transcription coupled coordinated ubiquitin

https://www.scirp.org/journal/paperinformation?paperid=36966

Crystal structure, biochemical and biophysical characterisation of NHR1 domain of E3 Ubiquitin...

Discover the role of Neuralized in Notch signaling and its interaction with Tom. Explore the crystal structure of NHR1 domain and its binding to PI4P. Gain...

crystal structure biochemical biophysical characterisation domain

https://www.ubiquitin-ligase.com/2018/08/17/6166/

Ubiquitin Ligase-ubiquitin-ligase.com

ubiquitin ligase com

https://www.frontiersin.org/journals/cell-and-developmental-biology/articles/10.3389/fcell.2024.1507725/full

Frontiers | E3 Siah ubiquitin ligase regulates dichotomous spermatogenesis in Sitotroga cerealella

Spermatogenesis in Lepidoptera holds significant importance due to its unique process of dichotomous spermatogenesis, yielding eupyrene and apyrene spermatoz...

ubiquitin ligase frontiers siah dichotomous spermatogenesis

https://elifesciences.org/reviewed-preprints/103945v3

Elevated Ubiquitin Phosphorylation by PINK1 Contributes to Proteasomal Impairment and Promotes...

elevated ubiquitin phosphorylation impairment

https://www.ncbi.nlm.nih.gov/gene?Db=gene&Cmd=ShowDetailView&TermToSearch=3093

UBE2K ubiquitin conjugating enzyme E2 K [Homo sapiens (human)] - Gene - NCBI

homo sapiens human gene ubiquitin enzyme k

https://elifesciences.org/articles/50903v1/peer-reviews

Peer review in Cycles of autoubiquitination and deubiquitination regulate the ERAD ubiquitin ligase...

peer review cycles regulate

https://www.wikidata.org/wiki/Q27655342

Structure of full-length ubiquitin-conjugating enzyme E2-25K (huntingtin-interacting protein 2) -...

full length structure ubiquitin enzyme huntingtin

https://pubmed.ncbi.nlm.nih.gov/31772299/

Therapeutic targeting of the E3 ubiquitin ligase SKP2 in T-ALL

ubiquitin ligase therapeutic targeting

https://www.ncbi.nlm.nih.gov/Structure/pdb/8ST7

8ST7: Structure of E3 ligase VsHECT bound to ubiquitin

E3 ubiquitin-protein ligase SopA-like catalytic domain-containing proteinUbiquitinprop-2-en-1-amine

structure ligase bound ubiquitin

https://www.ncbi.nlm.nih.gov/Structure/pdb/8SVJ

8SVJ: Ubiquitin variant i53: mutant VHH with 53BP1 Tudor domain

Tumor protein p53 binding protein 1Ubiquitin varient i53 mutant VHHGLYCEROL

tudor domain ubiquitin variant mutant vhh

https://www.rcsb.org/structure/2MJ5

RCSB PDB - 2MJ5: Structure of the UBA Domain of Human NBR1 in Complex with Ubiquitin

Structure of the UBA Domain of Human NBR1 in Complex with Ubiquitin

uba domain rcsb pdb structure human

https://www.ncbi.nlm.nih.gov/Structure/pdb/1VJV

1VJV: Crystal structure of Ubiquitin carboxyl-terminal hydrolase 6 (yfr010w) from Saccharomyces...

Ubiquitin carboxyl-terminal hydrolase 6

crystal structure carboxyl terminal ubiquitin hydrolase

https://pubmed.ncbi.nlm.nih.gov/17588518/

Ubiquitin- and ATP-independent proteolytic turnover of p21 by the REGgamma-proteasome pathway

We previously demonstrated that the proteasome activator REGgamma directs degradation of the steroid receptor coactivator SRC-3 by the 20S proteasome in an...

ubiquitin atp independent proteolytic turnover

https://elifesciences.org/articles/98070v1

DTX3L ubiquitin ligase ubiquitinates single-stranded nucleic acids | eLife

Biochemical and structural analyses reveal direct ubiquitin modification of single-stranded nucleic acids, catalysed by the DTX3L ubiquitin ligase.

ubiquitin ligase single stranded nucleic acids ubiquitinates elife

https://www.frontiersin.org/journals/physiology/articles/10.3389/fphys.2023.1134339/full

Frontiers | Identification of hypertrophy-modulating Cullin-RING ubiquitin ligases in primary...

Cullin-RING ubiquitin ligases (CRL) regulate numerous biological processes in the heart and have been implicated in regulating cardiac hypertrophy. This stud...

ubiquitin ligases frontiers identification hypertrophy modulating

https://www.ncbi.nlm.nih.gov/Structure/pdb/2OB4

2OB4: Human Ubiquitin-Conjugating Enzyme CDC34

Ubiquitin-conjugating enzyme E2-32 kDa complementing

human ubiquitin enzyme

https://www.rcsb.org/structure/2NBU

RCSB PDB - 2NBU: Solution structure of the Rad23 ubiquitin-like (UBL) domain

Solution structure of the Rad23 ubiquitin-like (UBL) domain

rcsb pdb solution structure ubiquitin

https://elifesciences.org/articles/07217

Nur77 prevents excessive osteoclastogenesis by inducing ubiquitin ligase Cbl-b to mediate NFATc1...

Orphan nuclear receptor Nur77 protects bone by enabling a timely termination of osteoclast differentiation.

ubiquitin ligase excessive osteoclastogenesis inducing cbl

https://pubmed.ncbi.nlm.nih.gov/26354440/

Using protein motion to read, write, and erase ubiquitin signals

Eukaryotes use a tiny protein called ubiquitin to send a variety of signals, most often by post-translationally attaching ubiquitins to substrate proteins and...

using protein motion read write

https://pubmed.ncbi.nlm.nih.gov/12808096/

Rapid turnover of extracellular signal-regulated kinase 3 by the ubiquitin-proteasome pathway...

Mitogen-activated protein (MAP) kinases are stable enzymes that are mainly regulated by phosphorylation and subcellular targeting. Here we report that...

rapid turnover extracellular signal regulated

https://www.ncbi.nlm.nih.gov/protein/2BGF_A

Chain A, DI-UBIQUITIN - Protein - NCBI

chain di ubiquitin protein ncbi

https://emcore.ucsf.edu/publications/interactions-regulatory-antibodies-modulate-chip-e3-ubiquitin-ligase-driven-tau

Interactions with regulatory antibodies modulate CHIP E3 ubiquitin ligase-driven tau clearance. |...

ubiquitin ligase interactions regulatory antibodies modulate

https://pubmed.ncbi.nlm.nih.gov/11504708/

Expression and localization of the CDC34 ubiquitin-conjugating enzyme in pediatric acute...

expression localization ubiquitin enzyme

https://www.ncbi.nlm.nih.gov/protein/2BGF_B

Chain B, DI-UBIQUITIN - Protein - NCBI

chain b di protein

https://www.semanticscholar.org/topic/ubiquitin-precursor/8785675

ubiquitin precursor | Semantic Scholar

semantic scholar ubiquitin precursor

https://www.ncbi.nlm.nih.gov/Structure/pdb/9B5T

9B5T: Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (singly Ub-loaded) -...

UbiquitinUbiquitin-activating enzyme E1 1Ubiquitin-conjugating enzyme E2 4ADENOSINE-5'-TRIPHOSPHATEMAGNESIUM ION

ubiquitin tetrahedral intermediate mimic singly

https://pubmed.ncbi.nlm.nih.gov/39125654/

Crosstalk among Alternative Polyadenylation, Genetic Variants and Ubiquitin Modification Contribute...

Ubiquitin modification and alternative polyadenylation play crucial roles in the onset and progression of cancer. Hence, this study aims to comprehensively and...

alternative polyadenylation crosstalk among genetic variants

https://www.rcsb.org/structure/1WGG

RCSB PDB - 1WGG: Solution Structure of the N-terminal Ubiquitin-like Domain of Mouse Ubiquitin...

Solution Structure of the N-terminal Ubiquitin-like Domain of Mouse Ubiquitin Specific Protease 14 (USP14)

the n rcsb pdb solution structure

https://www.helsinki.fi/en/infrastructures/national-plant-phenotyping/news/genomic-and-phenomic-screens-for-flower-related-ring-type-ubiquitin-e3-ligases-in-arabidopsis

Genomic And Phenomic Screens for Flower Related RING Type Ubiquitin E3 Ligases In Arabidopsis |...

Frontiers in Plant Science doi: 10.3389/fpls.2017.00416

genomic phenomic screens flower related

https://www.frontiersin.org/journals/physiology/articles/10.3389/fphys.2022.968927/full

Frontiers | The regulatory roles of the E3 ubiquitin ligase NEDD4 family in DNA damage response

E3 ubiquitin ligases, an important part of ubiquitin proteasome system, catalyze the covalent binding of ubiquitin to target substrates, which plays a role i...

ubiquitin ligase frontiers regulatory roles

https://www.rcsb.org/structure/1XO3

RCSB PDB - 1XO3: Solution Structure of Ubiquitin like protein from Mus Musculus

Solution Structure of Ubiquitin like protein from Mus Musculus

rcsb pdb solution structure ubiquitin

https://www.rcsb.org/structure/8Q7R

RCSB PDB - 8Q7R: Ubiquitin ligation to substrate by a cullin-RING E3 ligase & Cdc34:...

Ubiquitin ligation to substrate by a cullin-RING E3 ligase & Cdc34: NEDD8-CUL2-RBX1-ELOB/C-FEM1C with trapped UBE2R2~donor UB-Sil1 peptide

rcsb pdb ubiquitin ligation substrate

https://www.rcsb.org/structure/8PMQ

RCSB PDB - 8PMQ: Catalytic module of yeast GID E3 ligase bound to multiphosphorylated Ubc8~ubiquitin

Catalytic module of yeast GID E3 ligase bound to multiphosphorylated Ubc8~ubiquitin

rcsb pdb catalytic module yeast

https://www.ncbi.nlm.nih.gov/protein/7BII_B

Chain B, E3 ubiquitin-protein ligase HUWE1 - Protein - NCBI

chain b protein ligase

https://www.muni.cz/en/research/publications/2211224

Role of Nse1 Subunit of SMC5/6 Complex as a Ubiquitin Ligase | Masaryk University

as a role subunit complex

https://pubmed.ncbi.nlm.nih.gov/16633365/

Ubiquitin ligases: cell-cycle control and cancer

A driving force of the cell cycle is the activation of cyclin-dependent kinases (CDKs), the activities of which are controlled by the ubiquitin-mediated...

ubiquitin ligases cell cycle control cancer

https://www.frontiersin.org/journals/veterinary-science/articles/10.3389/fvets.2024.1455338/full

Frontiers | Differential analysis of ubiquitin-proteomics in skeletal muscle of Duroc pigs and...

Understanding the differences in ubiquitination-modified proteins between Duroc pigs and Tibetan fragrant pigs is crucial for comprehending the growth and de...

skeletal muscle frontiers differential analysis ubiquitin

https://pubmed.ncbi.nlm.nih.gov/35394523/

Structural basis for the linkage specificity of ubiquitin-binding domain and deubiquitinase

Ubiquitination is a post-translational modification system essential for regulating a wide variety of biological processes in eukaryotes. Ubiquitin (Ub) itself...

ubiquitin binding domain structural basis linkage specificity

https://pubmed.ncbi.nlm.nih.gov/34332032/

Molecular functions of autophagy adaptors upon ubiquitin-driven mitophagy

Although mitophagy is recognized as one of the selective autophagy pathways that removes dysfunctional mitochondria, a more nuanced understanding of the...

molecular functions autophagy adaptors upon

https://pubmed.ncbi.nlm.nih.gov/21624359/

The E3 ubiquitin ligase Cullin 4A regulates meiotic progression in mouse spermatogenesis

The Cullin-RING ubiquitin-ligase CRL4 controls cell cycle and DNA damage checkpoint response and ensures genomic integrity. Inactivation of the Cul4 component...

ubiquitin ligase cullin meiotic progression

https://www.ncbi.nlm.nih.gov/Structure/pdb/5E6J

5E6J: Structure of SARS PLpro bound to a Lys48-linked di-ubiquitin activity based probe

Polyubiquitin-BReplicase polyprotein 1abubiquitinACETATE IONNICKEL (II) ION

structure sars plpro bound linked

https://elifesciences.org/reviewed-preprints/98070v2

DTX3L ubiquitin ligase ubiquitinates single-stranded nucleic acids

ubiquitin ligase single stranded nucleic acids ubiquitinates

https://www.ncbi.nlm.nih.gov/Structure/pdb/8V26

8V26: H2BK120ub-modified nucleosome ubiquitin position 2

601 DNA (147-MER)Histone H2AHistone H2B 1.1Histone H3.2Histone H4Ubiquitin

modified nucleosome ubiquitin position

https://pubmed.ncbi.nlm.nih.gov/17016436/

Ubiquitin E3 ligase WWP1 as an oncogenic factor in human prostate cancer

The gene for E3 ubiquitin ligase WWP1 is located at 8q21, a region frequently amplified in human cancers, including prostate cancer. Recent studies have shown...

ubiquitin ligase oncogenic factor human

https://www.ncbi.nlm.nih.gov/Structure/pdb/8R5H

8R5H: Ubiquitin ligation to neosubstrate by a cullin-RING E3 ligase & Cdc34:...

Bromodomain-containing protein 4Cullin-2E3 ubiquitin-protein ligase RBX1, N-terminally processedElongin-BElongin-CUbiquitinUbiquitin-conjugating enzyme E2...

ubiquitin ligation cullin ring