ubiquitin - Robuta Search

https://www.wikidata.org/wiki/Q36568828 A ubiquitin-conjugating enzyme in fission yeast that is essential for the onset of anaphase in... scientific article published on June 1997 https://www.ncbi.nlm.nih.gov/Structure/pdb/4ZPZ 4ZPZ: Crystal Structure of Semi-synthetic Ubiquitin with Phospho-Ser65 and Ala46Cys crystal structure semi synthetic https://www.wikidata.org/wiki/Q48051302 Ubiquitin C-terminal hydrolase is an immediate-early gene essential for long-term facilitation in... scientific article published in April 1997 https://www.ncbi.nlm.nih.gov/Structure/pdb/8HJE 8HJE: Vismodegib binds to the catalytical domain of human Ubiquitin-Specific Protease 28 https://www.ncbi.nlm.nih.gov/protein/5FG1_A Chain A, E3 ubiquitin-protein ligase listerin - Protein - NCBI ubiquitin protein ligase chain e3 ncbi https://www.ncbi.nlm.nih.gov/protein/8IKT_A Chain A, E3 ubiquitin-protein ligase parkin - Protein - NCBI ubiquitin protein ligase chain e3 parkin ncbi https://www.ncbi.nlm.nih.gov/Structure/pdb/6OQ2 6OQ2: NMR Structure of Branched K11/K48-Linked Tri-Ubiquitin nmr structure branched k11 k48 https://www.wikidata.org/wiki/Q24319011 Cloning of human ubiquitin-conjugating enzymes UbcH6 and UbcH7 (E2-F1) and characterization of... https://www.rcsb.org/structure/4PIJ RCSB PDB - 4PIJ: X-ray crystal structure of the K11S/K63S double mutant of ubiquitin X-ray crystal structure of the K11S/K63S double mutant of ubiquitin x ray crystal structure https://www.mdpi.com/1422-0067/21/22/8719 E3 Ubiquitin Ligase APC/CCdh1 Negatively Regulates FAH Protein Stability by Promoting Its... Fumarylacetoacetate hydrolase (FAH) is the last enzyme in the degradation pathway of the amino acids tyrosine and phenylalanine in mammals that catalyzes the... e3 ubiquitin ligase https://www.thermofisher.com/antibody/primary/panther/positive%20regulation%20of%20proteasomal%20ubiquitin-dependent%20protein%20catabolic%20process positive regulation of proteasomal ubiquitin-dependent protein catabolic process Antibodies |... Antibodies for proteins involved in positive regulation of proteasomal ubiquitin-dependent protein catabolic process pathways, according to their Panther/Gene... positive regulation ubiquitin dependent protein catabolic https://www.wikidata.org/wiki/Q48015939 The ubiquitin pathway in Parkinson's disease - Wikidata scientific article published on October 1, 1998 parkinson s disease ubiquitin pathway wikidata https://www.ncbi.nlm.nih.gov/protein/5UJL_B Chain B, Ubiquitin - Protein - NCBI chain b protein https://www.ncbi.nlm.nih.gov/protein/2KTF_A Chain A, Ubiquitin - Protein - NCBI chain ubiquitin protein ncbi https://elifesciences.org/articles/13841v1 A SPOPL/Cullin-3 ubiquitin ligase complex regulates endocytic trafficking by targeting EPS15 at... https://elifesciences.org/articles/26886/peer-reviews Peer review in USP5/Leon deubiquitinase confines postsynaptic growth by maintaining ubiquitin... Maintenance of ubiquitin homeostasis is essential for proper control of the size of postsynaptic density and the growth of specialized membrane structure. peer review https://pmc.ncbi.nlm.nih.gov/articles/PMC46461/ Crystal structure of a ubiquitin-dependent degradation substrate: a three-disulfide form of... Covalent attachment of ubiquitin marks substrates for proteolysis, but features that identify ubiquitination targets such as chicken egg white lysozyme are... crystal structure ubiquitin https://www.scirp.org/journal/paperinformation?paperid=37006 Ubiquitin-conjugating enzyme involved in the immune response caused by pathogens invasion Ubiquitin-proteasome pathway (UPP) is a significant way of protein degradation and modification in eukaryotic cell and involved in a complex series of... ubiquitin conjugating enzyme the immune https://www.ncbi.nlm.nih.gov/protein/2CRC_A Chain A, Ubiquitin conjugating enzyme 7 interacting protein 3 - Protein - NCBI ubiquitin conjugating enzyme chain 7 interacting protein https://www.rcsb.org/structure/2W9N RCSB PDB - 2W9N: crystal structure of linear di-ubiquitin crystal structure of linear di-ubiquitin rcsb pdb crystal structure linear di ubiquitin https://elifesciences.org/articles/85727 A TRAF-like E3 ubiquitin ligase TrafE coordinates ESCRT and autophagy in endolysosomal damage... The Dictyostelium discoideum TRAF6 homolog TrafE coordinates the autophagy and ESCRT membrane repair machineries and works in the major cell-autonomous... https://www.rcsb.org/structure/1CMX RCSB PDB - 1CMX: STRUCTURAL BASIS FOR THE SPECIFICITY OF UBIQUITIN C-TERMINAL HYDROLASES STRUCTURAL BASIS FOR THE SPECIFICITY OF UBIQUITIN C-TERMINAL HYDROLASES https://www.ncbi.nlm.nih.gov/Structure/pdb/8SSI 8SSI: Structure of Burkholderia pseudomallei deubiquitinase TssM in complex with ubiquitin Deubiquitinase TssMUbiquitinGLYCEROLprop-2-en-1-amine burkholderia pseudomallei structure https://www.ncbi.nlm.nih.gov/protein/2KWV_B Chain B, Ubiquitin - Protein - NCBI chain b protein https://pmc.ncbi.nlm.nih.gov/articles/PMC10163937/ Ubiquitin proteasome system in immune regulation and therapeutics - PMC The ubiquitin proteasome system (UPS) is a proteolytic machinery for the degradation of protein substrates that are post-translationally conjugated with... ubiquitin proteasome system immune regulation therapeutics pmc https://elifesciences.org/articles/57306 Interaction mapping of endoplasmic reticulum ubiquitin ligases identifies modulators of innate... Interaction mapping of ubiquitin ligase complexes embedded in the endoplasmic reticulum membrane has identified interactors of RNF26 that influence innate... endoplasmic reticulum ubiquitin ligases interaction mapping identifies https://elifesciences.org/articles/00459/figures Figures and data in The ART-Rsp5 ubiquitin ligase network comprises a plasma membrane quality... Ubiquitin ligase adaptors target the selective clearance of misfolded plasma membrane proteins. https://pmc.ncbi.nlm.nih.gov/articles/PMC16329/ A MHC-encoded ubiquitin-like protein (FAT10) binds noncovalently to the spindle assembly checkpoint... Recently a number of nonclass I genes were discovered in the human MHC class I region. One of these, FAT10, encodes a protein consisting of two domains with... https://www.spandidos-publications.com/10.3892/or.2016.4605/abstract Cullin-5, a ubiquitin ligase scaffold protein, is significantly underexpressed in endometrial... Oncology Reports is an international journal devoted to fundamental and applied research in Oncology. 5 a ubiquitin ligase scaffold protein https://www.wikidata.org/wiki/Q77752816 One ring to rule a superfamily of E3 ubiquitin ligases - Wikidata scientific article published on 01 April 1999 one ring to rule ubiquitin ligases https://elifesciences.org/articles/26886v1 USP5/Leon deubiquitinase confines postsynaptic growth by maintaining ubiquitin homeostasis through... usp5 leon deubiquitinase confines postsynaptic https://www.rcsb.org/structure/5CVN RCSB PDB - 5CVN: WDR48 (2-580):USP46~ubiquitin ternary complex WDR48 (2-580):USP46~ubiquitin ternary complex rcsb pdb 2 580 ubiquitin ternary complex https://www.rcsb.org/structure/3V6E RCSB PDB - 3V6E: Crystal Structure of USP2 and a mutant form of Ubiquitin Crystal Structure of USP2 and a mutant form of Ubiquitin rcsb pdb crystal structure https://www.ncbi.nlm.nih.gov/gene/1184744 hopAB2 type III secretion system effector E3 ubiquitin-protein ligase HopAB2 [Pseudomonas syringae... type iii secretion system ubiquitin protein ligase https://elifesciences.org/reviewed-preprints/96353 Spatiotemporal recruitment of the ubiquitin-specific protease USP8 directs endosome maturation ubiquitin specific protease of the spatiotemporal recruitment https://www.rcsb.org/structure/9LQM RCSB PDB - 9LQM: Crystal structure of synthetic ubiquitin variant R4 designed by ProteinMPNN Crystal structure of synthetic ubiquitin variant R4 designed by ProteinMPNN https://elifesciences.org/articles/07217 Nur77 prevents excessive osteoclastogenesis by inducing ubiquitin ligase Cbl-b to mediate NFATc1... Orphan nuclear receptor Nur77 protects bone by enabling a timely termination of osteoclast differentiation. https://www.thermofisher.com/antibody/product/Ubiquitin-Antibody-clone-UBB-1748-Monoclonal/7314-MSM1-P1 Ubiquitin Monoclonal Antibody (UBB, 1748) (7314-MSM1-P1) Detect Ubiquitin in WB, IHC (P), ICC/IF, ELISA, IHC (F). Reacts with Rabbit, Mouse, Goat, Sheep, Bovine. Advanced verification by Peptide array. Catalog #... monoclonal antibody ubiquitin ubb 1748 7314 https://www.rcsb.org/structure/2MRO RCSB PDB - 2MRO: Structure of the complex of ubiquitin and the UBA domain from DNA-damage-inducible... Structure of the complex of ubiquitin and the UBA domain from DNA-damage-inducible 1 protein (Ddi1) https://www.ncbi.nlm.nih.gov/gene/79876 UBA5 ubiquitin like modifier activating enzyme 5 [Homo sapiens (human)] - Gene - NCBI https://elifesciences.org/reviewed-preprints/88466v1 E3 ubiquitin ligase Deltex facilitates the expansion of Wingless gradient and antagonizes Wingless... e3 ubiquitin ligase https://www.thermofisher.com/antibody/primary/panther/positive%20regulation%20of%20free%20ubiquitin%20chain%20polymerization positive regulation of free ubiquitin chain polymerization Antibodies | Invitrogen Antibodies for proteins involved in positive regulation of free ubiquitin chain polymerization pathways, according to their Panther/Gene Ontology Classification positive regulation free ubiquitin chain polymerization https://www.jci.org/articles/view/92914 JCI - Recurrent ubiquitin B silencing in gynecological cancers establishes dependence on ubiquitin C ubiquitin b https://www.rcsb.org/structure/2NQ3 RCSB PDB - 2NQ3: Crystal structure of the C2 Domain of Human Itchy Homolog E3 Ubiquitin Protein... Crystal structure of the C2 Domain of Human Itchy Homolog E3 Ubiquitin Protein Ligase https://www.rcsb.org/structure/5K16 RCSB PDB - 5K16: Crystal structure of free Ubiquitin-specific protease 12 Crystal structure of free Ubiquitin-specific protease 12 ubiquitin specific protease rcsb pdb crystal structure https://www.thermofisher.com/antibody/primary/panther/protein%20targeting%20to%20vacuole%20involved%20in%20ubiquitin-dependent%20protein%20catabolic%20process%20via%20the%20multivesicular%20body%20sorting%20pathway protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the... Antibodies for proteins involved in protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting... protein targeting https://pmc.ncbi.nlm.nih.gov/articles/PMC42185/ Phosphorylation of ubiquitin-activating enzyme in cultured cells - PMC Ubiquitin-activating enzyme, E1, is the first enzyme in the pathway leading to formation of ubiquitin-protein conjugates. E1 exists as two isoforms in human... ubiquitin activating enzyme cultured cells phosphorylation pmc https://pmc.ncbi.nlm.nih.gov/articles/PMC1751334/ Three Ubiquitin Conjugation Sites in the Amino Terminus of the Dopamine Transporter Mediate Protein... Dopamine levels in the brain are controlled by the plasma membrane dopamine transporter (DAT). The amount of DAT at the cell surface is determined by the... https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2023.1123244/full Frontiers | The E3 ubiquitin ligases regulate PD-1/PD-L1 protein levels in tumor microenvironment... The tumor microenvironment (TME) is the tumor surrounding environment, which is critical for tumor development and progression. TME is also involved in clini... https://www.pearson.com/channels/biochemistry/exam-prep/asset/3f7bde2b/how-many-amino-acid-residues-does-ubiquitin-contain How many amino acid residues does ubiquitin contain? | Study Prep in Pearson+ How many amino acid residues does ubiquitin contain? amino acid residues how many https://www.wikidata.org/wiki/Q41669001 Pathways of ubiquitin conjugation - Wikidata scientific article published on December 1, 1997 pathways ubiquitin conjugation wikidata https://pmc.ncbi.nlm.nih.gov/articles/PMC8607428/ E3 ubiquitin ligases: styles, structures and functions - PMC E3 ubiquitin ligases are a large family of enzymes that join in a three-enzyme ubiquitination cascade together with ubiquitin activating enzyme E1 and... ubiquitin ligases e3 styles structures functions https://www.semanticscholar.org/topic/ubiquitin-vinyl-sulfone/3436327 ubiquitin vinyl sulfone | Semantic Scholar vinyl sulfone ubiquitin semantic scholar https://www.pearson.com/channels/biochemistry/exam-prep/asset/29d50b0c/why-is-the-bond-between-ubiquitin-and-lysines-r-group-not-considered-a-peptide-b Why is the bond between ubiquitin and lysine's R group not consid... | Study Prep in Pearson+ Why is the bond between ubiquitin and lysine's R group not considered a peptide bond? https://www.mdpi.com/2073-4409/8/6/581 The Ubiquitin Proteasome System Is a Key Regulator of Pluripotent Stem Cell Survival and Motor... The ubiquitin proteasome system (UPS) plays an important role in regulating numerous cellular processes, and a dysfunctional UPS is thought to contribute to... https://elifesciences.org/articles/92757/peer-reviews Peer review in Commissureless acts as a substrate adapter in a conserved Nedd4 E3 ubiquitin ligase... Commissureless works with the Nedd4 E3 ubiquitin ligase to transiently degrade the Robo1 receptor to allow commissural axons to cross the midline. https://pmc.ncbi.nlm.nih.gov/articles/PMC7862229/ Ubiquitin signaling in cell cycle control and tumorigenesis - PMC Cell cycle progression is a tightly regulated process by which DNA replicates and cell reproduces. The major driving force underlying cell cycle progression is... cell cycle ubiquitin signaling control tumorigenesis https://www.wikidata.org/wiki/Q68268502 Specificity of binding of NH2-terminal residue of proteins to ubiquitin-protein ligase. Use of... scientific article published on 01 February 1988 ubiquitin protein ligase nh2 terminal https://www.jci.org/articles/view/68996/figure/3 JCI - Dysregulation of voltage-gated sodium channels by ubiquitin ligase NEDD4-2 in neuropathic pain voltage gated sodium channels https://elifesciences.org/articles/60660v1/figures Figures and data in The linear ubiquitin chain assembly complex LUBAC generates heterotypic... https://www.rcsb.org/structure/2HLW RCSB PDB - 2HLW: Solution Structure of the Human Ubiquitin-conjugating Enzyme Variant Uev1a Solution Structure of the Human Ubiquitin-conjugating Enzyme Variant Uev1a https://elifesciences.org/articles/71928v1/figures Figures and data in The E3 Ubiquitin Ligase Mindbomb1 controls planar cell polarity-dependent... https://www.ncbi.nlm.nih.gov/Structure/pdb/1D3Z 1D3Z: UBIQUITIN NMR STRUCTURE ubiquitin nmr structure https://www.ncbi.nlm.nih.gov/Structure/pdb/7YUI 7YUI: Crystal structure of HOIL-1L(195-423) in complex with the linear tetra-ubiquitin Polyubiquitin-CRanBP-type and C3HC4-type zinc finger-containing protein 1ZINC ION https://www.rcsb.org/structure/3JW0 RCSB PDB - 3JW0: E2~Ubiquitin-HECT rcsb pdb e2 ubiquitin hect https://elifesciences.org/articles/76763/peer-reviews Peer review in Multiple UBX proteins reduce the ubiquitin threshold of the mammalian p97-UFD1-NPL4... UBX proteins reduce the ubiquitin threshold of mammalian p97-UFD1-NPL4. https://pmc.ncbi.nlm.nih.gov/articles/PMC11238939/ Age-Dependent Differences in Blood Levels of Glial Fibrillary Acidic Protein but Not Ubiquitin... Despite the growing evidence of the clinical utility of blood-brain biomarkers in adults with traumatic brain injury (TBI), less is known about the performance... https://www.wikidata.org/wiki/Q28287730 Novel predicted peptidases with a potential role in the ubiquitin signaling pathway - Wikidata https://www.rcsb.org/structure/5KYD RCSB PDB - 5KYD: Crystal structure of USP7 catalytic domain [V302K] mutant in complex with ubiquitin Crystal structure of USP7 catalytic domain [V302K] mutant in complex with ubiquitin https://www.jci.org/articles/view/197926/pdf JCI - Corrigendum to Ubiquitin-specific protease 7 sustains DNA damage response and promotes... ubiquitin specific protease https://www.scirp.org/journal/articles?searchcode=COP9+Signalosome%3B+CHOP%3B+Adipogenesis%3B+Cullin-RING+Ubiquitin+Ligase&searchfield=keyword&page=1 COP9 Signalosome; CHOP; Adipogenesis; Cullin-RING Ubiquitin Ligase - Articles - Scientific Research... COP9 Signalosome; CHOP; Adipogenesis; Cullin-RING Ubiquitin Ligase cop9 signalosome ubiquitin ligase chop adipogenesis cullin https://www.spandidos-publications.com/10.3892/or.2014.3695/abstract Ubiquitin ligase Siah1 promotes the migration and invasion of human glioma cells by regulating... Oncology Reports is an international journal devoted to fundamental and applied research in Oncology. https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2014.00262/full Frontiers | Does Antigen Masking by Ubiquitin Chains Protect from the Development of Autoimmune... Autoimmune diseases are characterized by the production of antibodies against self-antigens and generally arise from a failure of central or peripheral toler... https://www.rcsb.org/structure/6DXH RCSB PDB - 6DXH: Structure of USP5 zinc-finger ubiquitin binding domain co-crystallized with... Structure of USP5 zinc-finger ubiquitin binding domain co-crystallized with 4-(4-tert-butylphenyl)-4-oxobutanoate https://pmc.ncbi.nlm.nih.gov/articles/PMC44140/ Developmentally regulated loss of ubiquitin and ubiquitinated proteins during pollen maturation in... Eukaryotic cells typically contain 0.2-1.0% of their total protein as the highly conserved protein ubiquitin, which exists both free and covalently attached to... https://www.trimnet.eu/ TRIM-NET A training network in drug discovery targeting TRIM ubiquitin ligases | TRIM-NET training network drug discovery trim https://www.ncbi.nlm.nih.gov/protein/2L3R_A Chain A, E3 ubiquitin-protein ligase UHRF1 - Protein - NCBI ubiquitin protein ligase chain e3 uhrf1 ncbi https://www.helsinki.fi/en/researchgroups/plant-phenomics/news/genomic-and-phenomic-screens-for-flower-related-ring-type-ubiquitin-e3-ligases-in-arabidopsis Genomic and Phenomic Screens for Flower Related RING Type Ubiquitin E3 Ligases in Arabidopsis |... Our latest publication using the National Plant Phenotyping Infrastructure https://www.prlog.org/12886409-ubiquitin-enzymes-market-in-healthcare-market-is-thriving-worldwide-with-the-outstanding-player-2027.html Ubiquitin Enzymes Market in Healthcare Market Is Thriving Worldwide with the outstanding player... Ubiquitin Enzymes Market in Healthcare Market Is Thriving Worldwide with the outstanding player 2027. Ubiquitin Enzymes Market Report Analyses competitive... market in https://elifesciences.org/articles/71928v1/peer-reviews Peer review in The E3 Ubiquitin Ligase Mindbomb1 controls planar cell polarity-dependent convergent... https://www.wikidata.org/wiki/Q55060421 The protein substrate binding site of the ubiquitin-protein ligase system - Wikidata binding site ubiquitin ligase protein substrate system https://www.mdpi.com/1999-4915/16/12/1935 MARCH8 Restricts RSV Replication by Promoting Cellular Apoptosis Through Ubiquitin-Mediated... Numerous host factors function as intrinsic antiviral effectors to attenuate viral replication. MARCH8 is an E3 ubiquitin ligase that has been identified as a... cellular apoptosis restricts rsv replication https://pmc.ncbi.nlm.nih.gov/articles/PMC16202/ Functional overlap of sequences that activate transcription and signal ubiquitin-mediated... Many transcription factors, particularly those involved in the control of cell growth, are unstable proteins destroyed by ubiquitin-mediated proteolysis. In a... functional overlap sequences https://www.wikidata.org/wiki/Q82857335 A UbcH5/ubiquitin noncovalent complex is required for processive BRCA1-directed ubiquitination -... scientific article published on 01 March 2006 https://www.ncbi.nlm.nih.gov/protein/8G7V_D Chain D, E3 ubiquitin-protein ligase RNF135 - Protein - NCBI ubiquitin protein ligase chain e3 rnf135 ncbi https://www.ncbi.nlm.nih.gov/Structure/pdb/2K8B 2K8B: Solution structure of PLAA family ubiquitin binding domain (PFUC) cis isomer in complex with... Phospholipase A-2-activating proteinUbiquitin https://www.mdpi.com/1420-3049/27/15/4867 Antibody for Serine 65 Phosphorylated Ubiquitin Identifies PLK1-Mediated Phosphorylation of Mitotic... Deciphering the protein posttranslational modification (PTM) code is one of the greatest biochemical challenges of our time. Phosphorylation and ubiquitylation... https://www.wikidata.org/wiki/Q35036580 The p53-Mdm2 module and the ubiquitin system. - Wikidata p53 mdm2 module ubiquitin system https://www.thermofisher.com/antibody/product/Ubiquitin-Antibody-clone-1B4-UB-Monoclonal/MA5-28514 Ubiquitin Monoclonal Antibody (1B4-UB) | Invitrogen (MA5-28514) Detect Ubiquitin in WB, IHC (P), ICC/IF, ELISA, IHC (F). Reacts with Rabbit, Mouse, Goat, Sheep, Bovine. Cited in 1 publication. Catalog # MA5-28514 monoclonal antibody ubiquitin 1b4 invitrogen ma5 https://www.ncbi.nlm.nih.gov/protein/5HMK_A Chain A, E3 ubiquitin-protein ligase Mdm2 - Protein - NCBI ubiquitin protein ligase chain e3 mdm2 ncbi https://www.rcsb.org/structure/4CI3 RCSB PDB - 4CI3: Structure of the DDB1-CRBN E3 ubiquitin ligase bound to Pomalidomide Structure of the DDB1-CRBN E3 ubiquitin ligase bound to Pomalidomide https://www.wikidata.org/wiki/Q70870874 Isolation, characterization, and partial purification of a novel ubiquitin-protein ligase, E3.... scientific article published on 01 January 1996 ubiquitin protein ligase https://www.wikidata.org/wiki/Q24291032 Features of the parkin/ariadne-like ubiquitin ligase, HHARI, that regulate its interaction with the... https://www.ncbi.nlm.nih.gov/protein/2HLW_A Chain A, Ubiquitin-conjugating enzyme E2 variant 1 - Protein - NCBI ubiquitin conjugating enzyme variant 1 chain e2 protein https://elifesciences.org/articles/00459/peer-reviews Peer review in The ART-Rsp5 ubiquitin ligase network comprises a plasma membrane quality control... Ubiquitin ligase adaptors target the selective clearance of misfolded plasma membrane proteins. https://www.rcsb.org/structure/8G44 RCSB PDB - 8G44: Structure of HDAC6 zinc-finger ubiquitin binding domain in complex with... Structure of HDAC6 zinc-finger ubiquitin binding domain in complex with 3-(3-(2-(benzylamino)-2-oxoethyl)-4-oxo-3,4-dihydroquinazolin-2-yl)propanoic acid https://www.rcsb.org/structure/2L76 RCSB PDB - 2L76: Solution NMR structure of human NFATC2IP ubiquitin-like domain, NFATC2IP_244_338,... Solution NMR structure of human NFATC2IP ubiquitin-like domain, NFATC2IP_244_338, NESG target HT65A/OCSP target hs00387_244_338/SGC-toronto https://www.rcsb.org/structure/7US1 RCSB PDB - 7US1: Structure of parkin (R0RB) bound to two phospho-ubiquitin molecules Structure of parkin (R0RB) bound to two phospho-ubiquitin molecules https://www.ncbi.nlm.nih.gov/gene?term=494470 ARK2C arkadia (RNF111) C-terminal like ring finger ubiquitin ligase 2C [Homo sapiens (human)] -... https://www.jci.org/articles/view/140615 JCI - Gain-of-function mutation in ubiquitin ligase KLHL24 causes desmin degradation and dilatation... gain of function mutation