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https://biohub.org/blog/esm3-simulating-evolution/ ESM3: Simulating Evolution With a Language Model - Biohub Dec 13, 2025 - ESM3 is a generative AI model that simulates 500 million years of evolution, linking protein sequence, structure, and function. with alanguage modelesm3evolution https://www.evolutionaryscale.ai/blog/esm3-release Evolutionary Scale ยท ESM3: Simulating 500 million years of evolution with a language model years oflanguage modelscaleesm3million