https://www.semanticscholar.org/topic/Anti-FGFR2-Antibody-BAY1179470/12296444
Anti-FGFR2 Antibody BAY1179470 | Semantic Scholar
An antibody against the fibroblast growth factor receptor type 2 (FGFR2), with potential antineoplastic activity. Upon administration, the anti-FGFR2 antibody...
antifgfr2scholar
https://www.news-medical.net/news/20231228/Insilico-Medicine-develops-new-AI-generated-FGFR23-inhibitor-for-tissue-agnostic-solid-tumors.aspx
Insilico Medicine develops new AI-generated FGFR2/3 inhibitor for tissue-agnostic solid tumors
Dec 28, 2023 - Insilico Medicine ("Insilico"), a generative artificial intelligence (AI)-driven clinical-stage drug discovery company, today announced the nomination of...
https://www.jci.org/articles/view/68899
JCI - FGFR2 signaling underlies p63 oncogenic function in squamous cell carcinoma
squamous celljcifgfr2signalingp63
https://elifesciences.org/articles/104060
Blocking SHP2 benefits FGFR2 inhibitor and overcomes its resistance in FGFR2-amplified gastric...
Dual blocking SHP2 and FGFR2 can not only promote the targeted tumor-killing effects and overcome FGFR2 inhibitor resistance caused by feedback activation, but...
https://www.jci.org/assets/293891/powerpoint
JCI - FGFR2 signaling underlies p63 oncogenic function in squamous cell carcinoma
squamous celljcifgfr2signalingp63
https://www.massgeneral.org/cancer-center/clinician-resources/advances/secondary-fgfr2-mutations-drive-drug-resistance-to-fgfr-inhibitors-in-bile-duct-cancer
Secondary FGFR2 Mutations Drive Drug Resistance in Bile Duct Cancer
Can understanding the genetic mechanisms driving resistance to the FGFR inhibitor BGJ398 lead to better therapies for bile duct and other cancers? The Mass...
drug resistancebile ductsecondaryfgfr2mutations
https://www.thermofisher.com/antibody/product/FGFR2-Antibody-Polyclonal/PA1-31990
FGFR2 Polyclonal Antibody | Invitrogen (PA1-31990)
Detect FGFR2 in WB, ELISA, IHC (P), ICC/IF, Flow. Reacts with Mouse, Rabbit, Goat, Human. Catalog # PA1-31990
polyclonal antibodyfgfr2invitrogenpa131990
https://pmc.ncbi.nlm.nih.gov/articles/PMC6672025/
Tumor heterogeneity and acquired drug resistance in FGFR2-fusion-positive cholangiocarcinoma...
Cholangiocarcinoma is a highly aggressive and lethal malignancy, with limited treatment options available. Recently, FGFR inhibitors have been developed and...
tumor heterogeneitydrug resistanceacquired
https://www.rcsb.org/structure/8W3B
RCSB PDB - 8W3B: TAS-120 covalent structure with FGFR2 molecular brake mutant
TAS-120 covalent structure with FGFR2 molecular brake mutant
rcsb pdb
https://www.rcsb.org/structure/4WV1
RCSB PDB - 4WV1: Crystal structure of the FGFR2 D2 domain in complex with Fab 2B.1.3
Crystal structure of the FGFR2 D2 domain in complex with Fab 2B.1.3
https://www.muni.cz/en/research/publications/982600
p38 Inhibition ameliorates skin and skull abnormalities in Fgfr2 Beare-Stevenson mice. | Masaryk...
https://www.rcsb.org/structure/8U1F
RCSB PDB - 8U1F: FGFR2 Kinase Domain Bound to Irreversible Inhibitor Cmpd 10
FGFR2 Kinase Domain Bound to Irreversible Inhibitor Cmpd 10
rcsb pdb