Robuta

https://www.semanticscholar.org/topic/EWS-FLI1-fusion-protein/462828 EWS-FLI1 fusion protein | Semantic Scholar A fusion protein encoded by the EWSR1/FLI1 fusion gene. This protein is comprised of the transactivation domain of the RNA-binding protein EWS fused to the... fusion proteinewsfli1semanticscholar https://www.jci.org/articles/view/21197 JCI - FLI1 monoallelic expression combined with its hemizygous loss underlies... combined withjcifli1expressionhemizygous https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2020.00800/full Frontiers | Fli1 Downregulation in Scleroderma Myeloid Cells Has Profibrotic and Proinflammatory... Scleroderma is an autoimmune connective tissue disease characterized by immune dysregulation, vasculopathy and fibrosis. We have previously demonstrated that... myeloid cellsfrontiersfli1downregulationscleroderma https://www.jci.org/articles/view/21197/pdf JCI - FLI1 monoallelic expression combined with its hemizygous loss underlies... combined withjcifli1expressionhemizygous https://pmc.ncbi.nlm.nih.gov/articles/PMC11788431/ The O-glycosyltransferase C1GALT1 promotes EWSR1::FLI1 expression and is a therapeutic target for... Ewing sarcoma (ES) is an aggressive bone cancer driven by the oncogenic fusion-protein EWSR1::FLI1, which is not present in normal cells and is therefore an...