https://pmc.ncbi.nlm.nih.gov/articles/PMC8548812/
Berberine exerts its antineoplastic effects by reversing the Warburg effect via downregulation of...
Glucose transporter 1 (GLUT1) plays a primary role in the glucose metabolism of cancer cells. However, to the best of our knowledge, there are currently no...
https://www.spandidos-publications.com/10.3892/ijmm.2012.999/abstract
Protective effects of atorvastatin against oxidized LDL-induced downregulation of KLF expression in...
International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.
oxidized ldl
https://www.frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2022.861529/full
Frontiers | Regional Downregulation of Dopamine Receptor D1 in Bilateral Dorsal Lateral Geniculate...
As a popular eye disease, amblyopia is characterized by the low level of best corrected visual acuity. It starts from early childhood and leads to permanent ...
dopamine receptor d1
https://www.spandidos-publications.com/10.3892/or.2016.4823?text=fulltext
Downregulation of miR-34a contributes to the proliferation and migration of laryngeal carcinoma...
Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.
to the
https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2015.00111/full
Frontiers | Downregulation of MYCN through PI3K Inhibition in Mouse Models of Pediatric Neural...
The MYCN proto-oncogene is associated with poor outcome across a broad range of pediatric tumors. While amplification of MYCN drives subsets of high risk neu...
https://pmc.ncbi.nlm.nih.gov/articles/PMC6524349/
The Influence of Curcumin on the Downregulation of MYC, Insulin and IGF-1 Receptors: A Possible...
Background and objectives: Mounting evidence shows that curcumin, a bioactive substance originating from turmeric root, has anticancer properties....
https://www.jci.org/articles/view/66764/figure/1
JCI - ErbB3 downregulation enhances luminal breast tumor response to antiestrogens
breast tumorjcierbb3downregulationenhances
https://pmc.ncbi.nlm.nih.gov/articles/PMC110063/
Cytomegalovirus Inhibits the Engraftment of Donor Bone Marrow Cells by Downregulation of...
Cytomegalovirus (CMV) disease after bone marrow (BM) transplantation is often associated with BM graft failure. There are two possible reasons for such a...
bone marrow cellscytomegalovirus
https://elifesciences.org/articles/64564
Downregulation of glial genes involved in synaptic function mitigates Huntington's disease...
Cross-species transcriptomic analysis and high-throughput behavioral assays in a Drosophila model of Huntington's disease show that downregulation of glial...
https://www.spandidos-publications.com/10.3892/ijo_00000559/abstract
Downregulation of SS18-SSX1 expression in synovial sarcoma by small interfering RNA enhances the...
International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.
https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2021.682773/full
Frontiers | SPNS2 Downregulation Induces EMT and Promotes Colorectal Cancer Metastasis via...
Spinster homologue 2 (SPNS2), a transporter of S1P (sphingosine-1-phosphate), has been reported to mediate immune response, vascular development, and patholo...
colorectal cancerfrontiersspns2downregulationinduces
https://pmc.ncbi.nlm.nih.gov/articles/PMC11599744/
The dual actions of miRNA16a in restricting Bovine Coronavirus replication through downregulation...
The roles of host cell miRNAs have not been well studied in the context of BCoV replication and immune regulation. This study aimed to identify miRNA...
https://elifesciences.org/articles/110771
Retraction: PAK3 downregulation induces cognitive impairment following cranial irradiation | eLife
cognitive impairmentretractionpak3downregulationinduces
https://pmc.ncbi.nlm.nih.gov/articles/PMC3223558/
Reversible and regionally selective downregulation of brain cannabinoid CB1 receptors in chronic...
Chronic cannabis (marijuana, hashish) smoking can result in dependence. Rodent studies show reversible downregulation of brain cannabinoid CB1 (cannabinoid...
https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2021.749673/full
Frontiers | Upregulation of HSPA1A/HSPA1B/HSPA7 and Downregulation of HSPA9 Were Related to Poor...
The human HSP70 family is a member of the heat shock proteins (HSPs), consisting of 13 members encoded by the HSPA genes. HSPs play important roles in regula...
https://pmc.ncbi.nlm.nih.gov/articles/PMC8085306/
Role of mTOR-Regulated Autophagy in Synaptic Plasticity Related Proteins Downregulation and the...
Postoperative cognitive dysfunction increases mortality and morbidity in perioperative patients and has become a major concern for patients and caregivers....
https://www.spandidos-publications.com/10.3892/ol.2014.1904
Promoter hypermethylation and downregulation of trefoil factor 2 in human gastric cancer
Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.
trefoil factor 2
https://www.mdpi.com/2077-0383/10/4/890
Cigarette Smoking, miR-27b Downregulation, and Peripheral Artery Disease: Insights into the...
Cigarette smoking is a risk factor for the development of peripheral artery disease (PAD), although the proatherosclerotic mediators of cigarette smoking are...
peripheral artery diseasecigarette smoking
https://www.muni.cz/en/research/publications/1488089
miR-150 downregulation contributes to the high-grade transformation of follicular lymphoma by...
https://elifesciences.org/articles/92879/peer-reviews
Peer review in Downregulation of Mirlet7 miRNA family promotes Tc17 differentiation and emphysema...
Mirlet7 functions as a molecular brake of CD8+IL17a+ T cells (Tc17) inflammation and chronic obstructive pulmonary disease via direct regulation RAR-related...
https://elifesciences.org/articles/40396
NLRP12 suppresses hepatocellular carcinoma via downregulation of cJun N-terminal kinase activation...
NOD-like receptor NLRP12 is a critical regulator of hepatocyte proliferation and its activation could be therapeutically used to suppress hepatocellular...
hepatocellular carcinoma
https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2021.634542/full
Frontiers | Downregulation of METTL7B Inhibits Proliferation of Human Clear Cell Renal Cancer Cells...
Clear cell renal cell carcinoma (ccRCC) is the most aggressive urologic tumor, and its incidence is increasing. Identifying novel molecular biomarker for inh...
https://www.frontiersin.org/journals/genetics/articles/10.3389/fgene.2021.632164/full
Frontiers | Downregulation of hsa_circ_0004543 Activates oxLDL-Induced Vascular Endothelial Cell...
Circular RNAs (circRNAs) are novel non-coding RNAs, which show abnormal expression in several diseases, such as atherosclerosis (AS). The purpose of the pres...
https://elifesciences.org/articles/92879/figures
Figures and data in Downregulation of Mirlet7 miRNA family promotes Tc17 differentiation and...
Mirlet7 functions as a molecular brake of CD8+IL17a+ T cells (Tc17) inflammation and chronic obstructive pulmonary disease via direct regulation RAR-related...
https://www.wikidata.org/wiki/Q73434298
Grb2 downregulation leads to Akt inactivation in heregulin-stimulated and ErbB2-overexpressing...
scientific article published on 01 December 2000
https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2021.679348/full
Frontiers | Downregulation of miR-135b-5p Suppresses Progression of Esophageal Cancer and...
Esophageal cancer (EC) as one of the commonest human cancers, which accompany high morbidity. MicroRNAs (miRNAs) play a pivotal role in various cancers, incl...
esophageal cancerfrontiersdownregulationmir
https://www.goodtherapy.org/blog/biology-of-calm-how-downregulation-promotes-well-being-1027164
GoodTherapy | The Biology of Calm: How Downregulation Pro...
the biologycalmdownregulationpro
https://www.spandidos-publications.com/10.3892/ol.2019.11240/abstract
lncRNA SNHG7 affects malignant tumor behaviors through downregulation of EZH2 in uveal melanoma...
Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.
https://www.spandidos-publications.com/10.3892/or.2013.2731/abstract
Cisplatin regulates SH-SY5Y cell growth through downregulation of BDNF via miR-16
Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.
https://edubirdie.com/docs/boston-university/cas-bi-108-biology-2/86028-mechanism-underlying-downregulation-of-cbp-mll1
Mechanism Underlying Downregulation of CBP & MLL1 - Edubirdie
mechanismunderlyingdownregulationcbpmll1
https://elifesciences.org/articles/58053
Downregulation of the tyrosine degradation pathway extends Drosophila lifespan | eLife
The tyrosine degradation pathway reprogramming connects mitochondrial dysfunction, aging, and production of tyrosine-derived neuromediators that can be...
of thedownregulationtyrosinedegradationpathway
https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2017.00498/full
Frontiers | Iron- and Hepcidin-Independent Downregulation of the Iron Exporter Ferroportin in...
Retention of iron in tissues macrophages via upregulation of hepcidin (HAMP) and downregulation of the iron exporter ferroportin (FPN) is thought to particip...
of thefrontiersironhepcidinindependent
https://www.frontiersin.org/journals/cell-and-developmental-biology/articles/10.3389/fcell.2022.837000/full
Frontiers | A novel regulated network mediated by downregulation HIF1A-AS2 lncRNA impairs placental...
Preeclampsia (PE) is the predominant medical condition leading to maternal and fetal mortality, and the lack of effective treatment increases its risk to the...
https://www.spandidos-publications.com/10.3892/or.2015.3731/abstract
microRNA-206 attenuates tumor proliferation and migration involving the downregulation of NOTCH3 in...
Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.
https://www.spandidos-publications.com/10.3892/ijo.2023.5591/abstract
[Corrigendum] Downregulation of CD147 induces malignant melanoma cell apoptosis via the regulation...
International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.
malignant melanoma
https://pmc.ncbi.nlm.nih.gov/articles/PMC12796760/
Downregulation of ANPEP Is Associated with Aggressive Prostate Cancer and Poor Disease-specific...
Our study findings indicate that ANPEP is linked to markers that indicate a more aggressive disease profile, and that its expression may serve as a prognostic...
https://www.spandidos-publications.com/10.3892/ijo.2014.2314
Downregulation of the tumor suppressor HSPB7, involved in the p53 pathway, in renal cell carcinoma...
International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.
https://pmc.ncbi.nlm.nih.gov/articles/PMC3356833/
Insulin resistance due to nutrient excess: Is it a consequence of AMPK downregulation? - PMC
It has long been known that excesses of glucose and branched chain amino acids, such as leucine, lead to insulin resistance in skeletal muscle. A recent study...
https://www.jci.org/articles/view/119770
JCI - Changes in gene expression in the intact human heart. Downregulation of alpha-myosin heavy...
https://www.frontiersin.org/journals/cell-and-developmental-biology/articles/10.3389/fcell.2021.663130/full
Frontiers | Androgen Activity Is Associated With PD-L1 Downregulation in Thyroid Cancer
Thyroid cancer is the most prevalent endocrine malignancy in the US with greater than 53,000 new cases in 2020. There is a significant gender disparity in d...
associated with
https://www.spandidos-publications.com/10.3892/or.2013.2814?text=fulltext
Downregulation of Hsp70 inhibits apoptosis induced by sialic acid-binding lectin (leczyme)
Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.
https://www.spandidos-publications.com/10.3892/ijmm.2020.4744/abstract
Antihypertensive activity of oleanolic acid is mediated via downregulation of secretory...
International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.
oleanolic acidantihypertensiveactivitymediatedvia
https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2022.787897/full
Frontiers | ARID1A Downregulation Predicts High PD-L1 Expression and Worse Clinical Outcome in...
Background: Recent studies have confirmed that AT-rich interactive domain-containing protein 1A (ARID1A) plays a critical role in tumorigenesis, but its role...
https://www.spandidos-publications.com/10.3892/or.2013.2825?text=fulltext
Lapatinib alters the malignant phenotype of osteosarcoma cells via downregulation of the activity...
Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.
lapatinibaltersmalignantphenotype
https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2022.798639/full
Frontiers | Downregulation of PTEN Promotes Autophagy via Concurrent Reduction in Apoptosis in...
Cardiac hypertrophy is characterized by an increase in the size of the cardiomyocytes which is initially triggered as an adaptive response but ultimately bec...
reduction infrontiersdownregulationpten
https://www.spandidos-publications.com/10.3892/ijo.2014.2749/abstract
Downregulation of Msi1 suppresses the growth of human colon cancer by targeting p21cip1
International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.
https://www.spandidos-publications.com/10.3892/ijmm.2012.998/abstract
Adenovirus-mediated TRAIL expression and downregulation of Bcl-2 expression suppresses non-small...
International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.
https://pmc.ncbi.nlm.nih.gov/articles/PMC9736085/
Psychedelic-Induced Serotonin 2A Receptor Downregulation Does Not Predict Swim Stress Coping in...
Serotoninergic psychedelics such as psilocybin have been reported to elicit a long-lasting reduction in depressive symptoms. Although the main target for...
serotonin 2a receptor
https://www.spandidos-publications.com/10.3892/ijmm.2017.2955/abstract
Downregulation of miR-10b promotes osteoblast differentiation through targeting Bcl6
International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.
downregulationmir10bosteoblastdifferentiation
https://www.spandidos-publications.com/10.3892/or.2015.3743/abstract
Downregulation of SNAIL sensitizes hepatocellular carcinoma cells to TRAIL-induced apoptosis by...
Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.
hepatocellular carcinoma
https://www.proquest.com/docview/2674876514?pq-origsite=gscholar&fromopenview=true&sourcetype=Dissertations%20&%20Theses
Metabolic Downregulation During Diapause in Embryos of Artemia Franciscana - ProQuest
Explore millions of resources from scholarly journals, books, newspapers, videos and more, on the ProQuest Platform.
artemia franciscanametabolicdownregulationdiapauseembryos
https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2021.663225/full
Frontiers | CRISPR/Cas9 uPAR Gene Knockout Results in Tumor Growth Inhibition, EGFR Downregulation...
uPAR is a globular protein, tethered to the cell membrane by a GPI-anchor involved in several cancer-related properties and its overexpression commonly corre...
https://www.preprints.org/manuscript/202401.1560
Downregulation of TASK-3 Channel Induces Senescence of Granulosa Cells in the Bovine Follicular...
Ovarian cysts are linked to hormone imbalances and altered gene expressions, but the connection between cysts and ion channel expression is understudied. This...
https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2020.556908/full
Frontiers | ClC-5 Downregulation Induces Osteosarcoma Cell Apoptosis by Promoting Bax and tBid...
Osteosarcoma is the most common malignant bone tumor. Chloride (Cl-) channels-mediated Cl- movement plays an important role in regulating the functions of va...
https://www.spandidos-publications.com/10.3892/or.2016.4597/abstract
Effects of HSP27 downregulation on PDT resistance through PDT-induced autophagy in head and neck...
Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.