gefitinib - Robuta Search

https://pubmed.ncbi.nlm.nih.gov/17075123/ Molecular predictors of outcome with gefitinib in a phase III placebo-controlled study in advanced... EGFR gene copy number was a predictor of clinical benefit from gefitinib in ISEL. Additional studies are warranted to assess these biomarkers fully for the... https://adisinsight.springer.com/drugsafety/803153917?error=cookies_not_supported&code=9dc3b0ea-5aa4-4b33-97e8-47040878d021 Gefitinib - AdisInsight A 66-year-old woman developed pneumoperitoneum during gefitinib therapy [dosage not stated].The woman diagnosed with a history of metastatic lung adenocarcinoma gefitinib adisinsight https://researchconnect.buffalo.edu/en/publications/high-incidence-of-oral-dysesthesias-on-a-trial-of-gefitinib-pacli/ High incidence of oral dysesthesias on a trial of gefitinib, paclitaxel, and concurrent external... https://www.nice.org.uk/guidance/ta192/chapter/Update-information Update information | Gefitinib for the first-line treatment of locally advanced or metastatic... Evidence-based recommendations on gefitinib (Iressa) for untreated locally advanced or metastatic non-small-cell lung cancer in adults the first line https://pubmed.ncbi.nlm.nih.gov/34208076/ The Pharmacometabodynamics of Gefitinib after Intravenous Administration to Mice: A Preliminary... The effects of intravenous gefitinib (10 mg/kg), an anilinoquinazoline thymidylate kinase inhibitor (TKI), selective for the epidermal growth factor receptor... gefitinib https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2021.686445/full Frontiers | The Combination of Gefitinib With ATRA and ATO Induces Myeloid Differentiation in Acute... In approximately 15% of patients with acute myeloid leukemia (AML), total and phosphorylated EGFR proteins have been reported to be increased compared to hea... https://pubmed.ncbi.nlm.nih.gov/21660144/ Gefitinib in non small cell lung cancer Gefitinib is an oral, reversible, tyrosine kinase inhibitor of epidermal growth factor receptor (EGFR) that plays a key role in the biology of non small cell... small cell gefitinib non lung cancer https://adisinsight.springer.com/drugsafety/803928483?error=cookies_not_supported&code=274426fb-ffad-4eeb-a1e0-7f6f32fe07c2 Erlotinib/Gefitinib/Osimertinib - AdisInsight One hundred and eighty-seven patients [age and sex not stated] with non-small cell lung cancer at a super-tertiary centre in Thailand received erlotinib, erlotinib gefitinib osimertinib adisinsight https://pubmed.ncbi.nlm.nih.gov/20573926/ Gefitinib or chemotherapy for non-small-cell lung cancer with mutated EGFR First-line gefitinib for patients with advanced non-small-cell lung cancer who were selected on the basis of EGFR mutations improved progression-free survival,... small cell lung cancer https://adisinsight.springer.com/drugsafety/801009829?error=cookies_not_supported&code=67de67f9-3337-4f84-a4a9-35768863514d Gefitinib - AdisInsight A 59-year-old man developed lung disorders during treatment with gefitinib for progressive non-small cell lung cancer.The man started receiving gefitinib 250 gefitinib adisinsight https://researchconnect.buffalo.edu/en/publications/preclinical-pharmacokineticpharmacodynamic-models-of-gefitinib-an/ Preclinical pharmacokinetic/pharmacodynamic models of gefitinib and the design of equivalent dosing... and the preclinical pharmacokinetic models https://pubmed.ncbi.nlm.nih.gov/14581894/ Gefitinib (ZD1839) in previously treated advanced non-small-cell lung cancer: experience from a... In this single-center experience, gefitinib demonstrated clinically significant antitumor activity and provided good palliation in a predominantly pretreated... small cell lung cancer https://pmc.ncbi.nlm.nih.gov/articles/PMC10390488/ Knowledge-based mechanistic modeling accurately predicts disease progression with gefitinib in... Lung adenocarcinoma (LUAD) is associated with a low survival rate at advanced stages. Although the development of targeted therapies has improved outcomes in... knowledge based mechanistic modeling disease progression accurately https://pubmed.ncbi.nlm.nih.gov/19692680/ Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma Gefitinib is superior to carboplatin-paclitaxel as an initial treatment for pulmonary adenocarcinoma among nonsmokers or former light smokers in East Asia. The... gefitinib carboplatin paclitaxel pulmonary adenocarcinoma https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2018.00082/full Frontiers | Silencing of Long Non-coding RNA MIAT Sensitizes Lung Cancer Cells to Gefitinib by... Long non-coding RNA (lncRNA) myocardial infarction associated transcript (MIAT) was recently identified as oncogene in several cancers. However, the role of ... https://www.news-medical.net/news/2005/04/19/9298.aspx Clinical trial of gefitinib for advanced lung cancer closes early Jun 20, 2019 - Researchers have closed a randomized clinical trial comparing gefitinib (Iressa) vs. placebo following chemotherapy and radiation for patients with non-small... advanced lung cancer clinical trial gefitinib closes early https://adisinsight.springer.com/trials/700205889?error=cookies_not_supported&code=a8ae7b72-3a23-422d-b4bf-4f274123fd61 A phase I study of pemetrexed and gefitinib in chemotherapy naive elderly patients with non- small... This trial will investigate the tolerability and efficacy of gefitinib and pemetrexed in chemotherapy-naive elderly patients with non-small cell lung cancer https://edrn.cancer.gov/data-and-resources/publications/16288303-775-her3-genomic-gain-and-sensitivity-to-gefitinib-in-advanced-non-small-cell-lung-cancer-patients/ HER3 genomic gain and sensitivity to gefitinib in advanced non-small-cell lung cancer patients. This is a publication by a member of the Early Detection Research Network. https://adisinsight.springer.com/drugsafety/803094925?error=cookies_not_supported&code=000cb362-974a-4784-97d7-d62b5be89f2d Erlotinib/gefitinib - AdisInsight A 92-year-old man developed gastrointestinal bleeding while receiving erlotinib and gefitinib.The man was diagnosed with lung cancer and started on oral erlotinib gefitinib adisinsight https://research-repository.uwa.edu.au/en/publications/effects-of-gefitinib-an-epidermal-growth-factor-receptor-inhibito/ Effects of Gefitinib, an Epidermal Growth Factor Receptor Inhibitor, on Human Placental Cell Growth... epidermal growth factor https://edrn.cancer.gov/data-and-resources/publications/16707605-1104-epidermal-growth-factor-receptor-messenger-rna-expression-gene-dosage-and-gefitinib-sensitivity-in-non-small-cell-lung-cancer/ Epidermal growth factor receptor messenger RNA expression, gene dosage, and gefitinib sensitivity... This is a publication by a member of the Early Detection Research Network. epidermal growth factor messenger rna https://adisinsight.springer.com/drugsafety/803059663?error=cookies_not_supported&code=364d6ab4-bb4c-4e7d-92a7-24d9e75ee01a Carboplatin/gefitinib/paclitaxel - AdisInsight A 69-year-old woman with metastatic non-small cell lung cancer developed neutropenia and peripheral nerve damage during chemotherapy with carboplatin and carboplatin gefitinib paclitaxel adisinsight https://www.wikidata.org/wiki/Q83364741 Gefitinib-sensitizing mutations in esophageal carcinoma - Wikidata scientific article published on 01 May 2006 gefitinib sensitizing mutations esophageal carcinoma