Robuta

https://www.rcsb.org/structure/2YDR RCSB PDB - 2YDR: CpOGA D298N in complex with p53-derived O-GlcNAc peptide CpOGA D298N in complex with p53-derived O-GlcNAc peptide https://www.ncbi.nlm.nih.gov/Structure/pdb/5DJS 5DJS: Thermobaculum terrenum O-GlcNAc transferase mutant - K341M Tetratricopeptide TPR_2 repeat proteinURIDINE-5'-DIPHOSPHATE o glcnac transferasemutant https://www.ncbi.nlm.nih.gov/protein/2C1G_A Chain A, PEPTIDOGLYCAN GLCNAC DEACETYLASE - Protein - NCBI chainpeptidoglycanglcnacdeacetylaseprotein https://pmc.ncbi.nlm.nih.gov/articles/PMC18502/ The O-GlcNAc transferase gene resides on the X chromosome and is essential for embryonic stem cell... Nuclear and cytoplasmic protein glycosylation is a widespread and reversible posttranslational modification in eukaryotic cells. Intracellular glycosylation by... https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2014.00197/full Frontiers | Disruption of O-GlcNAc Cycling in C. elegans Perturbs Nucleotide Sugar Pools and... The carbohydrate modification of serine and threonine residues with O-linked beta-N-acetylglucosamine (O-GlcNAc) is ubiquitous and governs cellular processes... https://www.ncbi.nlm.nih.gov/Structure/pdb/5AC5 5AC5: GH20C, Beta-hexosaminidase from Streptococcus pneumoniae in complex with GlcNAc N-ACETYL-BETA-D-GLUCOSAMINIDASE1,2-ETHANEDIOL2-acetamido-2-deoxy-beta-D-glucopyranoseGLYCEROL beta hexosaminidasestreptococcus pneumoniae https://pmc.ncbi.nlm.nih.gov/articles/PMC11381892/ O-GlcNAc transferase congenital disorder of glycosylation (OGT-CDG): Potential mechanistic targets... O-GlcNAc transferase (OGT) is the sole enzyme responsible for the post-translational modification of O-GlcNAc on thousands of target nucleocytoplasmic... o glcnac transferasecongenital disorder https://elifesciences.org/articles/85464/peer-reviews Peer review in O-GlcNAc glycosylation orchestrates fate decision and niche function of bone marrow... OGT-mediated protein O-GlcNAcylation balances osteogenic versus adipogenic differentiation and controls hematopoietic niche function of bone marrow stromal... https://elifesciences.org/reviewed-preprints/107170 Pathogenic O-GlcNAc dyshomeostasis is associated with cortical malformations and hyperactivity o glcnacassociated withpathogenic https://www.rcsb.org/structure/6OHE RCSB PDB - 6OHE: Alpha-L-fucosidase AlfC D200A in complex with Fuca(1,6)GlcNAc Alpha-L-fucosidase AlfC D200A in complex with Fuca(1,6)GlcNAc https://pmc.ncbi.nlm.nih.gov/articles/PMC11717234/ Genetic gradual reduction of OGT activity unveils the essential role of O-GlcNAc in the mouse... The reversible glycosylation of nuclear and cytoplasmic proteins (O-GlcNAcylation) is catalyzed by a single enzyme, namely O-GlcNAc transferase (OGT). The... https://www.ncbi.nlm.nih.gov/gene/29571445 nagJ O-GlcNAc hydrolase NagJ [Clostridium perfringens ATCC 13124] - Gene - NCBI o glcnac hydrolaseclostridium perfringensatcc13124gene https://pmc.ncbi.nlm.nih.gov/articles/PMC9140282/ Intellectual disability-associated disruption of O-GlcNAc cycling impairs habituation learning in... O-GlcNAcylation is a reversible co-/post-translational modification involved in a multitude of cellular processes. The addition and removal of the O-GlcNAc... intellectual disabilityo glcnac https://www.muni.cz/vyzkum/publikace/1230883 Exploring the Reaction Mechanism of O-GlcNAc Transferase using QM/MM Molecular Dynamics |... o glcnac transferase https://www.ncbi.nlm.nih.gov/Structure/pdb/6WJ9 6WJ9: UDP-GlcNAc C4-epimerase mutant S121A/Y146F from Pseudomonas protegens in complex with... NAD-dependent epimerase/dehydratase family proteinNICOTINAMIDE-ADENINE-DINUCLEOTIDEURIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE https://www.rcsb.org/structure/8SNC RCSB PDB - 8SNC: Chlorella virus Hyaluronan Synthase bound to GlcA extended GlcNAc primer Chlorella virus Hyaluronan Synthase bound to GlcA extended GlcNAc primer https://oglcnac.org/ O-GlcNAc Database o glcnacdatabase https://pmc.ncbi.nlm.nih.gov/articles/PMC11784489/ Exploiting O-GlcNAc dyshomeostasis to screen O-GlcNAc transferase intellectual disability variants... O-GlcNAcylation is an essential protein modification catalyzed by O-GlcNAc transferase (OGT). Missense variants in OGT are linked to a novel intellectual... o glcnacintellectual disabilityexploitingscreentransferase https://www.ncbi.nlm.nih.gov/Structure/pdb/1FWY 1FWY: CRYSTAL STRUCTURE OF N-ACETYLGLUCOSAMINE 1-PHOSPHATE URIDYLTRANSFERASE BOUND TO UDP-GLCNAC UDP-N-ACETYLGLUCOSAMINE PYROPHOSPHORYLASE1,2-ETHANEDIOLSULFATE IONURIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE https://www.rcsb.org/structure/5NPS RCSB PDB - 5NPS: The human O-GlcNAc transferase in complex with a bisubstrate inhibitor The human O-GlcNAc transferase in complex with a bisubstrate inhibitor https://elifesciences.org/articles/85464v1 O-GlcNAc glycosylation orchestrates fate decision and niche function of bone marrow stromal... https://pmc.ncbi.nlm.nih.gov/articles/PMC6660750/ Catalytic deficiency of O-GlcNAc transferase leads to X-linked intellectual disability - PMC Protein O-GlcNAcylation is a posttranslational modification essential for development. Recently, mutations in the O-GlcNAc transferase (OGT) substrate binding... o glcnac transferase https://www.rcsb.org/structure/6P4M RCSB PDB - 6P4M: Salmonella typhi PltB Homopentamer with Neu5Ac-alpha-2-3-Gal-beta-1-4-GlcNAc... Salmonella typhi PltB Homopentamer with Neu5Ac-alpha-2-3-Gal-beta-1-4-GlcNAc Glycans https://www.ncbi.nlm.nih.gov/Structure/pdb/4WAD 4WAD: Crystal Structure of TarM with UDP-GlcNAc Glycosyl transferase, group 1 family protein1,2-ETHANEDIOLCHLORIDE IONURIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE crystal structuretarmudpglcnac https://www.ncbi.nlm.nih.gov/Structure/pdb/2FV1 2FV1: UGL_D88N/dGlcA-GlcNAc Unsaturated glucuronyl hydrolase2,6-anhydro-3-deoxy-L-threo-hex-2-enonic acid2-acetamido-2-deoxy-alpha-D-glucopyranose uglglcnac https://www.ncbi.nlm.nih.gov/Structure/pdb/7L66 7L66: C-type carbohydrate-recognition domain 4 of the mannose receptor complexed with Methyl-GlcNAc Macrophage mannose receptor 1CALCIUM IONmethyl 2-acetamido-2-deoxy-alpha-D-glucopyranoside