https://open.library.emory.edu/concern/publications/c769e572-3189-4f6b-989a-77fd47a75598
Engineered Hematopoietic Stem Cells as Therapeutics for Hemophilia A. | OpenEmory
Engineered Hematopoietic Stem Cells as Therapeutics for Hemophilia A.
hematopoietic stem cellsengineeredtherapeuticshemophilia
https://pubmed.ncbi.nlm.nih.gov/39108521/
Multi-omics Analysis of Umbilical Cord Hematopoietic Stem Cells from a Multi-ethnic Cohort of...
This study revealed the significant correlation between pre-pregnancy maternal obesity and multi-omics level molecular changes in the uHSCs of offspring,...
hematopoietic stem cells
https://www.repository.cam.ac.uk/items/44d89a4f-3bd4-4950-a9b5-ccd46da7bb17
Dual cholinergic signals regulate daily migration of hematopoietic stem cells and leukocytes.
Hematopoietic stem and progenitor cells (HSPCs) and leukocytes circulate between the bone marrow (BM) and peripheral blood following circadian oscillations....
hematopoietic stem cells
https://profiles.wustl.edu/en/publications/clonal-evolution-of-preleukemic-hematopoietic-stem-cells-in-acute/
Clonal evolution of preleukemic hematopoietic stem cells in acute myeloid leukemia - WashU Research...
hematopoietic stem cells
https://apice.unibo.it/xwiki/bin/view/Publication/AbmhscMasbio08?xpage=whatsnew
Lineage Commitment of Hematopoietic Stem Cells: An Agent-based Model / APICe
Lineage Commitment of Hematopoietic Stem Cells: An Agent-based Model
hematopoietic stem cellsan agentlineagecommitment
https://pubmed.ncbi.nlm.nih.gov/34525360/
Definitive hematopoietic stem cells minimally contribute to embryonic hematopoiesis
Hematopoietic stem cells (HSCs) are rare cells that arise in the embryo and sustain adult hematopoiesis. Although the functional potential of nascent HSCs is...
hematopoietic stem cellsdefinitivecontributeembryonichematopoiesis
https://www.frontiersin.org/journals/molecular-biosciences/articles/10.3389/fmolb.2024.1479605/full
Frontiers | Deciphering the evolving niche interactome of human hematopoietic stem cells from...
Hematopoietic stem cells (HSC) reside within specialized microenvironments that undergo dynamic changes throughout development and aging to support HSC funct...
hematopoietic stem cells
https://cordis.europa.eu/project/id/253463/results
Identification of novel factors to expand hematopoietic stem cells in vitro | NOVEXPAND | Project |...
Deliverables, publications, datasets, software, exploitable results
hematopoietic stem cells
https://pmc.ncbi.nlm.nih.gov/articles/PMC4021761/
Non-Hematopoietic Stem Cells in Umbilical Cord Blood - PMC
Allogeneic umbilical cord blood (UCB) transplantation has been used to treat a variety of malignant and non-malignant diseases. Recent studies show convincing...
hematopoietic stem cellsumbilical cord bloodnonpmc
https://scholars.duke.edu/publication/730063
Scholars@Duke publication: Transplantation of hematopoietic stem cells in human severe combined...
hematopoietic stem cells
https://www.cirm.ca.gov/about-cirm/publications/cd47-upregulated-circulating-hematopoietic-stem-cells-and-leukemia-cells-avoid-phagocytosis/
CD47 is upregulated on circulating hematopoietic stem cells and leukemia cells to avoid...
hematopoietic stem cells
https://pmc.ncbi.nlm.nih.gov/articles/PMC18476/
Hematopoietic stem cells and lymphoid progenitors express different Ikaros isoforms, and Ikaros is...
The generation of lymphoid cells in mice depends on the function of the Ikaros protein. Ikaros has been characterized as a lymphoid-restricted, zinc-finger...
hematopoietic stem cellslymphoid
https://www.wikidata.org/wiki/Q36375771
The role of apoptosis in the regulation of hematopoietic stem cells: Overexpression of Bcl-2...
hematopoietic stem cellsthe role
https://www.sciencedaily.com/releases/2020/12/201224113116.htm
Discovery of aging mechanism for hematopoietic stem cells | ScienceDaily
By transferring mouse aged hematopoietic stem cells (aged HSCs) to the environment of young mice (bone marrow niche), it was demonstrated that the pattern of...
hematopoietic stem cellsdiscoveryagingmechanismsciencedaily
https://www.wikidata.org/wiki/Q33833350
The purification and characterization of fetal liver hematopoietic stem cells. - Wikidata
hematopoietic stem cellspurificationcharacterization
https://scholarworks.indianapolis.iu.edu/items/1801dbc6-1f63-4c19-8861-fe3cafe2eda6
Role of S6K1 in regulating self-renewal of hematopoietic stem cells and propagatoin of leukemia
The development and function of hematopoietic stem cells (HSCs) is regulated by numerous signaling pathways including Akt-mechanistic target of rapamycin...
hematopoietic stem cells
https://pubmed.ncbi.nlm.nih.gov/17676974/
Aging hematopoietic stem cells decline in function and exhibit epigenetic dysregulation
Age-related defects in stem cells can limit proper tissue maintenance and hence contribute to a shortened lifespan. Using highly purified hematopoietic stem...
hematopoietic stem cellsagingdecline
https://fis.tu-dresden.de/portal/en/publications/fate-mapping-of-hematopoietic-stem-cellsreveals-two-pathways-of-native-thrombopoiesis(c1f5da3f-78e0-4da9-8183-5142bb861ea0).html
Fate mapping of hematopoietic stem cells reveals two pathways of native thrombopoiesis | TU Dresden
hematopoietic stem cells
https://www.cirm.ca.gov/our-progress/awards/identification-and-isolation-transplantable-human-hematopoietic-stem-cells-pluripotent-cell-lines-two-steps-primitive-hematopoiesis-transplantable-definitive-cells-and-non-toxic-cond/
Identification and isolation of transplantable human hematopoietic stem cells from pluripotent cell...
hematopoietic stem cells
https://www.techtransfer.nih.gov/patent/e-167-2001-1-us-03
Hematopoietic Stem Cells Regenerate Infarcted Myocardium | Technology Transfer
hematopoietic stem cellsregeneratemyocardiumtechnologytransfer
https://hsbiblio.uni-tuebingen.de/xmlui/handle/10900/133430
Hematopoietic Stem Cell Transplantation with Mesenchymal Stromal Cells in Children with...
stem cell transplantationstromal cellshematopoieticchildren
https://pubmed.ncbi.nlm.nih.gov/7479772/
The purification and characterization of fetal liver hematopoietic stem cells
Thy-1loSca-1+Lin-Mac-1+CD4- cells have been isolated from the livers of C57BL-Thy-1.1 fetuses. This population appears to be an essentially pure population of...
purificationcharacterizationfetalliverhematopoietic
https://pmc.ncbi.nlm.nih.gov/articles/PMC110379/
Human Immunodeficiency Virus Type 1 Vectors Efficiently Transduce Human Hematopoietic Stem Cells -...
Lentiviruses are potentially advantageous compared to oncoretroviruses as gene transfer agents because they can infect nondividing cells. We demonstrate here...
human immunodeficiency virustype
https://pubmed.ncbi.nlm.nih.gov/37733599/
Protocol for high-sensitivity western blot on murine hematopoietic stem cells
Hematopoietic stem cells (HSCs) sustain hematopoiesis during homeostasis and regeneration. However, their limited availability poses a challenge for protein...
high sensitivitywestern blotprotocol
https://www.frontiersin.org/journals/hematology/articles/10.3389/frhem.2024.1401713/full
Frontiers | Dissecting dormancy and quiescence in hematopoietic stem cells
Quiescence is a fundamental state of adult hematopoietic stem cells (HSCs) characterized by their residence in the G0 phase of the cell cycle. Despite being ...
frontiersdissectingdormancyquiescencehematopoietic
https://profiles.wustl.edu/en/publications/bortezomib-is-a-rapid-mobilizer-of-hematopoietic-stem-cells-in-mi/
Bortezomib is a rapid mobilizer of hematopoietic stem cells in mice via modulation of the...
https://www.news-medical.net/news/20201117/Researchers-discover-new-mechanism-that-enhances-the-hematopoietic-stem-cell-of-hematopoietic-stem-cells.aspx
Novel mechanism enhances the formation of hematopoietic stem cells
Nov 17, 2020 - Hematopoietic stem cells can replenish all the different cell types of our blood system. For this reason, hematopoietic stem cells are the cells used in many...
novelmechanismenhancesformationhematopoietic
https://pubmed.ncbi.nlm.nih.gov/25062640/
Barcoded vector libraries and retroviral or lentiviral barcoding of hematopoietic stem cells
Cellular barcoding is a relatively recent technique aimed at clonal analysis of a proliferating cell population of any kind. The method was shown to be...
https://fujifilmbiosciences.fujifilm.com/us/resources/turney-tl-et-al-2019-optimizing-cryopreservation-of-hematopoietic-stem-cells-collected-for-autologous-stem-cell-transplantation-in-patients-with-multiple-myeloma-cytotherapy.html
Turney TL et al. (2019) Optimizing cryopreservation of hematopoietic stem cells collected for...
Turney TL et al. (2019) Optimizing cryopreservation of hematopoietic stem cells collected for autologous stem cell transplantation in patients with multiple...
https://pubmed.ncbi.nlm.nih.gov/38754428/
Autophagy counters inflammation-driven glycolytic impairment in aging hematopoietic stem cells
Autophagy is central to the benefits of longevity signaling programs and to hematopoietic stem cell (HSC) response to nutrient stress. With age, a subset of...
autophagycountersinflammationdriven
https://www.cordis.europa.eu/project/id/256452/reporting/es
Global microRNA profiling of normal and Pbx1-null hematopoietic stem cells and progenitors for the...
Latest report summary
https://www.frontiersin.org/journals/genome-editing/articles/10.3389/fgeed.2023.1141618/full
Frontiers | High-efficiency editing in hematopoietic stem cells and the HUDEP-2 cell line based on...
Genome editing tools, such as CRISPR/Cas, TALE nucleases and, more recently, double-strand-break-independent editors, have been successfully used for gene th...
https://pubmed.ncbi.nlm.nih.gov/24693133/
Modulation of pathological phenotype of red blood cells generated ex vivo from hematopoietic stem...
Modulation of pathological phenotype of red blood cells generated ex vivo from hematopoietic stem cells in patients with sickle cell disease
red blood cells
https://www.techtransfer.nih.gov/patent/e-053-2019-0-cn-10
GENETICALLY MODIFIED HEMATOPOIETIC STEM AND PROGENITOR CELLS (HSPCs) AND MESENCHYMAL CELLS AS A...
genetically modifiedprogenitor cellshematopoieticstem
https://fujifilmbiosciences.fujifilm.com/us/primary-stem-cells/hematopoietic-cells.html
Hematopoietic Cells - Primary & Stem Cells
FUJIFILM Biosciences is a global life sciences and medical media provider with an array of innovative products to assist your advances in healthcare.
hematopoietic cellsprimarystem
https://www.cirm.ca.gov/our-progress/awards/ex-vivo-gene-editing-human-hematopoietic-stem-cells-treatment-x-linked-hyper-igm-syndrome/
Ex Vivo Gene Editing of Human Hematopoietic Stem Cells for the Treatment of X-Linked Hyper-IgM...
https://www.frontiersin.org/journals/genome-editing/articles/10.3389/fgeed.2022.997142/full
Frontiers | Hematopoietic stem and progenitors cells gene editing: Beyond blood disorders
Lessons learned from decades-long practice in the transplantation of hematopoietic stem and progenitor cells (HSPCs) to treat severe inherited disorders or c...
gene editingfrontiershematopoieticstemprogenitors
https://pubmed.ncbi.nlm.nih.gov/3980993/
Identification of cell surface antigens present on murine hematopoietic stem cells
Nine antigens found on murine bone marrow cells were examined to define their pattern of expression in murine hematopoietic differentiation. Lymphocyte...
cell surface antigensidentification
https://portal.research.lu.se/en/publications/method-for-programming-differentiated-cells-into-hematopoietic-st/
Method for Programming Differentiated Cells into Hematopoietic Stem Cells - Lund University
methodprogrammingdifferentiatedcellshematopoietic
https://pubmed.ncbi.nlm.nih.gov/21561312/
Hematopoietic stem/progenitor cells express functional mitochondrial energy-dependent cystic...
Bone marrow-derived hematopoietic stem/progenitor cells (HSPCs) encompass a wide array of cell subsets with different capacities of engraftment and injured...
progenitor cellshematopoieticstemexpressfunctional
https://data.mendeley.com/datasets/snbcc8bh78/1
Elevated mitochondrial mass and low mitochondrial turnover capacity in hematopoietic stem cells....
In this study we show that efflux of a mitochondrial content-reporting dye leads to the erroneous conclusion that HSCs have low mitochondrial content. Using...
elevatedmitochondrialmasslow
https://publikationen.bibliothek.kit.edu/110103824
Hematopoietic and mesenchymal stem cells: Polymeric nanopartic...
The combination of stem cell therapy and nanoparticles promises to enhance the effect of cellular therapies by using nanocarriers as drug delivery devices to g
mesenchymal stem cellshematopoieticpolymeric
https://umu.diva-portal.org/smash/record.jsf?faces-redirect=true&language=en&searchType=SIMPLE&query=&af=%5B%5D&aq=%5B%5B%5D%5D&aq2=%5B%5B%5D%5D&aqe=%5B%5D&pid=diva2%3A1058965&noOfRows=50&sortOrder=author_sort_asc&sortOrder2=title_sort_asc&onlyFullText=false&sf=all
Prdm16 is a physiologic regulator of hematopoietic stem cells.
is aregulatorhematopoieticstemcells
https://www.techtransfer.nih.gov/patent/e-053-2019-0-cn-11
GENETICALLY MODIFIED HEMATOPOIETIC STEM AND PROGENITOR CELLS (HSPCs) AND MESENCHYMAL CELLS AS A...
genetically modifiedprogenitor cellshematopoieticstem
https://eprints.ncl.ac.uk/72798
The fate of human Langerhans cells in hematopoietic stem cell transplantation - ePrints - Newcastle...
https://cordis.europa.eu/project/id/865803/it
Intrapopulation communication and collective cell decisions of hematopoietic stem cells |...
Hematopoietic stem cells (HSCs) contribute to blood cell production throughout life and are found at rare, yet tightly regulated frequencies in adult bone...
communicationcollectivecelldecisionshematopoietic
https://www.wikidata.org/wiki/Q47891319
Homeobox gene expression profile in human hematopoietic multipotent stem cells and T-cell...
scientific article published in June 2003
https://pubmed.ncbi.nlm.nih.gov/35551452/
Runx1 and Runx2 inhibit fibrotic conversion of cellular niches for hematopoietic stem cells
In bone marrow, special microenvironments, known as niches, are essential for the maintenance of hematopoietic stem cells (HSCs). A population of mesenchymal...
https://www.cordis.europa.eu/project/id/256452/es
Global microRNA profiling of normal and Pbx1-null hematopoietic stem cells and progenitors for the...
MicroRNAs (miRNAs) are non-coding RNA molecules that repress translation and stability of target mRNAs. They are key regulators of cell cycle and...
https://udspace.udel.edu/items/be71848c-e365-46a6-a459-ba7188daab1d
Megakaryocyte-membrane wrapped nanoparticles for targeted delivery to hematopoietic stem cells
Hematopoietic Stem and Progenitor Cells (HSPCs) are promising targets for gene therapy as they are self-renewing and differentiate into many blood-related...
membranewrappednanoparticles