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https://www.breastcancer.org/podcast/her2-positive-recurrence HER2-Positive Breast Cancer Recurrence Marleen Meyers, MD talks about HER2-positive disease and specific ways to reduce its risk of recurrence. her2 positive breast cancer recurrence https://www.esmo.org/oncology-news/fda-approves-pembrolizumab-for-her2-positive-gastric-or-gastro-oesophageal-junction-adenocarcinoma-expressing-pd-l1-cps-1 FDA Approves Pembrolizumab for HER2 Positive Gastric or Gastro-oesophageal Junction Adenocarcinoma... gastro oesophageal junction her2 positive https://www.gene.com/media/news-features/perjeta-approved-for-her2-positive-metastatic-breast-cancer Genentech: News Features | Perjeta Approved For HER2-Positive Metastatic Breast Cancer Access media kits and related information for our featured news stories. news features her2 positive genentech perjeta approved https://www.cancer.gov/news-events/cancer-currents-blog/2021/enhertu-her2-metastatic-breast-cancer Enhertu Effective in HER2-Positive Metastatic Breast Cancer - NCI In people with metastatic HER2-positive breast cancer, the targeted drug trastuzumab deruxtecan (Enhertu) markedly lengthened progression-free survival... metastatic breast cancer her2 positive enhertu effective nci https://www.news-medical.net/news/20220830/Leukemia-drug-successfully-disrupts-HER2-positive-brain-metastasis-in-animal-studies.aspx Leukemia drug successfully disrupts HER2-positive brain metastasis in animal studies Aug 30, 2022 - In animal studies led by researchers at Duke Cancer Institute, a drug approved to treat leukemia successfully disrupted the ability of HER2-positive breast... her2 positive brain metastasis leukemia drug successfully https://www.cancer.gov/news-events/cancer-currents-blog/2017/trastuzumab-emtansine-breast-cancer Trastuzumab Emtansine for HER2-Positive Breast Cancer - NCI An NCI Cancer Currents blog on results from the TH3RESA and EMILIA clinical trials showing trastuzumab emtansine (T-DM1) improved overall survival in patients... her2 positive breast cancer trastuzumab emtansine nci https://www.mdanderson.org/cancerwise/her2-positive-breast-cancer-survivor--i-believe-in-md-anderson.h00-159303045.html HER2-positive breast cancer survivor: I believe in MD Anderson | UT MD Anderson Jennifer Smith didn't come to MD Anderson first for her HER2-positive breast cancer treatment, but she wishes she had. her2 positive breast cancer believe in md anderson survivor https://www.herconnection.com/ HER2-Positive Breast Cancer Support | HERConnection her2 positive breast cancer support https://pmc.ncbi.nlm.nih.gov/articles/PMC10093019/ Emerging Targeted Therapies for HER2-Positive Breast Cancer - PMC HER2-positive breast cancer (BC), which accounts for ~20% of BC, is one of the more aggressive and has the worst overall survival rate among them. These... her2 positive breast cancer targeted therapies emerging pmc https://www.fda.gov/drugs/resources-information-approved-drugs/fda-approves-fam-trastuzumab-deruxtecan-nxki-her2-positive-gastric-adenocarcinomas FDA approves fam-trastuzumab deruxtecan-nxki for HER2-positive gastric adenocarcinomas | FDA On January 15, 2021, the Food and Drug Administration approved fam-trastuzumab deruxtecan-nxki (Enhertu, Daiichi Sankyo) for adult patients with locally... fam trastuzumab deruxtecan her2 positive fda approves https://www.aacr.org/blog/tag/her2-positive-breast-cancer/ HER2-positive breast cancer Archives - American Association for Cancer Research (AACR) her2 positive breast cancer american association for research archives aacr https://www.cancer.gov/publications/dictionaries/cancer-terms/def/her2-positive?cid=eb_govdel_cancerinfo Definition of HER2 positive - NCI Dictionary of Cancer Terms - NCI NCI's Dictionary of Cancer Terms provides easy-to-understand definitions for words and phrases related to cancer and medicine. definition of her2 positive nci dictionary cancer https://www.breastcancer.org/research-news/fda-approves-herceptin-biosimilar-trazimera FDA Approves Herceptin Biosimilar Trazimera to Treat HER2-Positive Breast Cancer In March 2019, the FDA approved Trazimera, a biosimilar for Herceptin, to treat people diagnosed with HER2-positive breast cancer. her2 positive fda approves herceptin biosimilar https://www.preprints.org/manuscript/202401.0437 HER2 Positive Early Breast Cancer: Time for Ultimate De-escalation?[v1] | Preprints.org De-escalation is currently taking place both in surgical and systemic treatment of breast cancer. The introduction of trastuzumab, the first monoclonal... early breast cancer https://www.fda.gov/drugs/resources-information-approved-drugs/fda-approves-imlunestrant-er-positive-her2-negative-esr1-mutated-advanced-or-metastatic-breast FDA approves imlunestrant for ER-positive, HER2-negative, ESR1-mutated advanced or metastatic... On September 25, 2025, the Food and Drug Administration approved imlunestrant (Inluriyo, Eli Lilly and Company), an estrogen receptor antagonist, for adults... https://pmc.ncbi.nlm.nih.gov/articles/PMC7375662/ Cardiac monitoring in HER2-positive patients on trastuzumab treatment: A review and implications... Trastuzumab prolongs progression-free and overall survival in patients with human epidermal growth factor receptor 2 (HER2) positive breast cancer. However,... https://www.mskcc.org/cancer-care/clinical-trials/24-282 A Phase 2 Study of Zongertinib in People With HER2-Positive Advanced Solid Tumors | Memorial Sloan... Full Title Beamion PANTUMOR-1: A Phase II, Multicentre, Multicohort, Open-Label Trial to Evaluate the Efficacy and Safety of Oral Zongertinib (BI 1810631) for... https://www.hmpgloballearningnetwork.com/site/onc/news/anbenitamab-plus-chemotherapy-significantly-improves-survival-previously-treated-her2 Anbenitamab Plus Chemotherapy Significantly Improves Survival in Previously Treated HER2-Positive... Anbenitamab plus chemotherapy significantly improved OS and PFS, with a threefold higher response rate vs chemotherapy alone, in patients with previously... plus chemotherapy significantly improves https://www.esmo.org/oncology-news/trastuzumab-deruxtecan-prolongs-os-in-second-line-treatment-for-patients-with-her2-positive-metastatic-gastric-or-gej-adenocarcinoma Trastuzumab Deruxtecan Prolongs OS in Second-Line Treatment for Patients with HER2-positive... second line treatment https://www.fda.gov/drugs/resources-information-approved-drugs/fda-approves-imlunestrant-er-positive-her2-negative-esr1-mutated-advanced-or-metastatic-breast?ref=onyxnewsroom.com FDA approves imlunestrant for ER-positive, HER2-negative, ESR1-mutated advanced or metastatic... On September 25, 2025, the Food and Drug Administration approved imlunestrant (Inluriyo, Eli Lilly and Company), an estrogen receptor antagonist, for adults... https://www.aacr.org/about-the-aacr/newsroom/news-releases/hr-positive-her2-negative-breast-cancer-patients-with-high-risk-of-recurrence-may-benefit-from-addition-of-anthracyclines-to-taxane-based-chemotherapy/ HR-positive, HER2-negative Breast Cancer Patients With High Risk of Recurrence May Benefit From... Dec 13, 2024 - Genomic testing helped identify which patients with node-negative, HR-positive, HER2- negative breast cancer could benefit from the addition of anthracyclines... her2 negative breast cancer https://www.breastcancer.org/research-news/kadcyla-improves-survival-for-some-mets-dx Kadcyla Improves Survival in Women Diagnosed With Metastatic, HER2-Positive Disease That's Stopped... The TH3RESA study found that Kadcyla improved overall survival in women diagnosed with metastatic, HER2-positive breast cancer that had stopped responding to... https://www.biospace.com/press-releases/tharimmune-announces-positive-data-with-novel-biparatopic-pd-1-vegf-and-multispecific-her2-her3-biologics-leveraging-proprietary-epiclicktm-technology Tharimmune Announces Positive Data with Novel Biparatopic PD-1/VEGF and Multispecific HER2/HER3... https://www.fda.gov/drugs/resources-information-approved-drugs/fda-approves-vepdegestrant-er-positive-her2-negative-esr1-mutated-advanced-or-metastatic-breast FDA approves vepdegestrant for ER-positive, HER2-negative, ESR1-mutated advanced or metastatic... FDA approves vepdegestrant for ER-positive, HER2-negative, ESR1-mutated advanced or metastatic breast cancer https://www.breastcancer.org/research-news/2-studies-confirm-kadcylas-benefits Final Results From Two Studies Confirm Kadcyla's Benefits for Advanced-Stage HER2-Positive Disease Final results from the EMILIA and TH3RESA studies show that Kadcyla improves overall survival in people diagnosed with advanced-stage HER2-positive breast... https://www.sciencedaily.com/releases/2010/12/101210091103.htm Pertuzumab and trastuzumab combination improved efficacy for women with HER2-positive breast cancer... The combination of pertuzumab and trastuzumab had superior antitumor activity in women with early HER2-positive breast cancer, according to Phase II study... https://www.breastcancer.org/podcast/kisqali-monaleesa-2 Kisqali Plus Femara Seems Best Option for Advanced-Stage Hormone-Receptor-Positive HER2-Negative... Dr. Gabriel Hortobagyi discusses overall survival results from the MONALEESA-2 trial. https://www.breastcancer.org/research-news/herceptin-plus-tykerb-no-better-than-alone Herceptin Plus Tykerb After Surgery No Better Than Herceptin Alone for Early-Stage, HER2-Positive... Women diagnosed with early-stage, HER2-positive breast cancer treated with both Herceptin and Tykerb after surgery had the same disease-free survival as women... https://www.nice.org.uk/guidance/TA1153 Overview | Zanidatamab for treating HER2-positive advanced biliary tract cancer after 1 or more... Evidence-based recommendations on zanidatamab (Ziihera) for treating HER2-positive advanced biliary tract cancer after 1 or more lines of systemic treatment in... https://www.gsk.com/en-gb/media/press-releases/phase-iii-study-in-her2-positive-advanced-breast-cancer-shows-overall-survival-benefit-when-tykerb-is-combined-with-paclitaxel/ Phase III study in HER2-positive advanced breast cancer shows overall survival benefit when Tykerb... https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2025.1473620/full Frontiers | A case report of HER2-positive descending colon cancer with peritoneal metastasis and... Human epidermal growth factor receptor 2 (HER2) is an anti-cancer drug target for colon cancer. Among patients with colorectal malignancy (colorectal cancer,... https://www.cancerresearchuk.org/about-cancer/find-a-clinical-trial/a-trial-of-buparalisib-for-advanced-breast-cancer-that-is-hormone-receptor-positive-and-her2-negative-belle2 A trial of buparlisib for advanced breast cancer that is hormone receptor positive and HER2... This trial looked at a drug called buparlisib for breast cancer that had spread into tissue surrounding the breast or elsewhere in the body. https://www.medicaldaily.com/herceptin-tyverb-her2-positive-breast-cancer-378099 Drug Combination Of Herceptin And Tyverb Obliterate HER2 Positive Breast Cancer Tumors In 11 Days Mar 16, 2016 - At a recent conference, researchers from the Institute of Cancer Research in London explain how a drug combination worked to dramatically shrink cancer tumors... https://www.cancer.gov/research/participate/clinical-trials-search/v?id=NCI-2026-01854&r=1 A Study Using ctDNA to Guide Treatment for People with HER2-positive Breast Cancer, HERizon-Breast... A Study Using ctDNA to Guide Treatment for People with HER2-positive Breast Cancer, HERizon-Breast Trial https://www.breastcancer.org/research-news/tx-regimens-before-surgery-to-omit-chemo Can Treatment Regimens Before Surgery for Early-Stage HER2-Positive Breast Cancer Omit Chemotherapy? Treatment before surgery with chemotherapy, Herceptin, and Perjeta seems to be more effective than the combination of Kadcyla and Perjeta before surgery. her2 positive breast cancer https://www.hmpgloballearningnetwork.com/site/jcp/videos/hr-positive-and-her2-negative-breast-cancer-treatment-updates HR-Positive and HER2-Negative Breast Cancer Treatment Updates William J. Gradishar, MD, details the latest advancements in the treatment of hormone receptor-positive (HR+), human epidermal growth factor receptor... her2 negative breast cancer hr positive treatment updates https://www.breastcancer.org/research-news/herceptin-plus-taxol-reduces-recurrence Herceptin Plus Taxol Reduces Recurrence Risk of Small HER2-Positive Breast Cancers Results from an early study suggest that a combination of Herceptin and Taxol reduce the risk of recurrence of small HER2-positive breast cancers that haven't... https://www.cancer.gov/research/participate/clinical-trials-search/v?id=NCI-2025-06351&r=1 Avasopasem for the Treatment of Patients with Metastatic Hormone Receptor Positive, HER2 Negative... Avasopasem for the Treatment of Patients with Metastatic Hormone Receptor Positive, HER2 Negative Breast Cancer with Progression on a CDK4/6 Inhibitor and... https://www.cancer.gov/research/participate/clinical-trials-search/v?id=NCI-2017-01119 Testing the Drug Atezolizumab or Placebo with Usual Therapy in First-Line HER2-Positive Metastatic... Testing the Drug Atezolizumab or Placebo with Usual Therapy in First-Line HER2-Positive Metastatic Breast Cancer https://www.nice.org.uk/guidance/ta612 Overview | Neratinib for extended adjuvant treatment of hormone receptor-positive, HER2-positive... Evidence-based recommendations on neratinib (Nerlynx) for extended adjuvant treatment of hormone receptor-positive, human epidermal growth factor receptor 2... hormone receptor positive adjuvant treatment overview neratinib extended https://www.aacr.org/about-the-aacr/newsroom/news-releases/adding-tucatinib-to-first-line-maintenance-therapy-delayed-disease-progression-in-her2-positive-metastatic-breast-cancer-in-her2climb-05-trial/ Adding Tucatinib to First-line Maintenance Therapy Delayed Disease Progression in HER2-positive... Dec 10, 2025 - Benefit was seen across all subgroups, including in patients with brain metastasis. Results from the phase III clinical trial was presented at SABCS 2025. https://www.mayo.edu/research/clinical-trials/cls-20149893 MM-302 Plus Trastuzumab vs. Chemotherapy of Physician's Choice Plus Trastuzumab in HER2-Positive... Learn more about services at Mayo Clinic. https://www.breastcancer.org/research-news/kadcyla-vs-herceptin-for-early-stage-her2-pos Kadcyla Seems Better Than Herceptin for Early-Stage, HER2-Positive Residual Breast Cancer For early-stage, HER2-Positive residual breast cancer, Kadcyla seems better than Herceptin https://www.breastcancer.org/research-news/herceptin-offers-long-lasting-benefits Study Shows Herceptin Offers Long-Lasting Benefits for Early-Stage, HER2-Positive Disease Results from an analysis of two large, long-term studies show that adding Herceptin to chemotherapy to treat women diagnosed with early-stage HER2-positive... https://www.pharmaceutical-technology.com/data-insights/myj-1633-immunisbio-human-epidermal-growth-factor-receptor-2-positive-breast-cancer-her2-breast-cancer-likelihood-of-approval/ MYJ-1633 by Immunisbio for Human Epidermal Growth Factor Receptor 2 Positive Breast Cancer (HER2+... Dec 29, 2024 - MYJ-1633 is under clinical development by Immunisbio and currently in Phase II for Human Epidermal Growth Factor Receptor 2 Positive Breast Cancer (HER2+... https://www.breastcancer.org/research-news/chemo-for-some-triple-pos-bc-improves-survival Chemotherapy for Certain Small, Hormone-Receptor-Positive, HER2-Positive Breast Cancers Seems to... A study suggests that women diagnosed with cancers 8-10 mm in size had better survival when they were treated with chemotherapy after surgery. hormone receptor positive for certain https://www.preprints.org/manuscript/202112.0441 Determining the Factors Predicting the Response to Anti-HER2 Therapy in HER2-Positive Breast Cancer... Background: We aimed to identify overexpressed genes or related pathways associated with good responses to anti-HER2 therapy and to suggest a model for... https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2023.1272602/full Frontiers | Treatment options for patients with hormone receptor-positive, HER2-negative... Breast cancer is the most commonly diagnosed cancer in women worldwide. Over the past decade, the treatment paradigm for patients with metastatic breast canc... hormone receptor positive treatment options for patients frontiers https://www.cancerresearchuk.org/about-cancer/find-a-clinical-trial/a-trial-looking-trastuzumab-pertuzumab-for-her2-positive-breast-cancer-aphinity A trial looking at trastuzumab and pertuzumab for HER2 positive breast cancer - APHINITY This trial is looking at adding a new drug called pertuzumab to trastuzumab for people who have had surgery for breast cancer. her2 positive breast cancer