https://pmc.ncbi.nlm.nih.gov/articles/PMC12180692/
Efficacy and Safety of Inclisiran in Adolescents With Genetically Confirmed Homozygous Familial...
Homozygous familial hypercholesterolemia (HoFH) is a genetic disease characterized by high levels of low-density lipoprotein cholesterol (LDL-C) present from...
efficacy and safety
https://pmc.ncbi.nlm.nih.gov/articles/PMC44442/
Localization of a putative tumor suppressor gene by using homozygous deletions in melanomas - PMC
The p21 region of human chromosome 9 is thought to contain a gene (MLM) involved in genetic susceptibility to melanoma and a gene or genes that influence...
https://elifesciences.org/articles/16078v1
Homozygous YME1L1 mutation causes mitochondriopathy with optic atrophy and mitochondrial network...
optic atrophyhomozygousyme1l1mutationcauses
https://www.acc.org/Latest-in-Cardiology/Clinical-Trials/2020/07/20/13/44/ODYSSEY-HoFH
Study in Participants With Homozygous Familial Hypercholesterolemia - American College of Cardiology
Dharam J. Kumbhani, MD, SM, FACC
study infamilial hypercholesterolemiaamerican collegeparticipantshomozygous
https://www.wikidata.org/wiki/Q71381844
Inactivation of the CDKN2 gene by homozygous deletion and de novo methylation is associated with...
scientific article published on 01 September 1996
https://www.businesswire.com/news/home/20230502005890/en/New-Family-Heart-Foundation-Study-Reveals-Systemic-Underdiagnosis-and-Undertreatment-of-Homozygous-Familial-Hypercholesterolemia
New Family Heart Foundation Study Reveals Systemic Underdiagnosis and Undertreatment of Homozygous...
A new study from the Family Heart Foundation, a leading research and advocacy organization, showed the diagnosis and treatment of homozygous familial hyperch...
new familyheart foundation
https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2022.862022/full
Frontiers | Novel Homozygous CYP27B1 Gene Mutation in Vitamin D-Dependent Rickets Type 1A (VDDR1A)...
Background: Vitamin D-dependent rickets type 1A (VDDR1A) rickets is an uncommon kind of rickets that affects both boys and girls. Genetic testing by a highly...
https://www.mdpi.com/2077-0383/8/4/476
Adapting Cord Blood Collection and Banking Standard Operating Procedures for HLA-Homozygous Induced...
In this article, we will discuss the main aspects to be considered to define standard operation procedures (SOPs) for the creation of an induced pluripotent...
standard operating procedures
https://www.biospace.com/press-releases/lib-therapeutics-announces-publication-of-phase-3-study-of-lerodalcibep-in-homozygous-familial-hypercholesterolemia-hofh-in-lancet-diabetes-endocrinology
LIB Therapeutics Announces Publication of Phase 3 Study of Lerodalcibep in Homozygous Familial...
phase 3 study
https://www.acc.org/Education-and-Meetings/Patient-Case-Quizzes/Homozygous-Familial-Hypercholesterolemia
Homozygous Familial Hypercholesterolemia: Genetic Abnormalities | Patient Case Quiz - American...
familial hypercholesterolemiagenetic abnormalitieshomozygouspatientcase
https://pmc.ncbi.nlm.nih.gov/articles/PMC8281499/
Adult glut3 Homozygous Null Mice Survive to Demonstrate Neural Excitability and Altered...
Since GLUT3 is vital for fueling neurotransmission, we examined in-vivo the adult phenotype carrying the conditional homozygous glut3 gene mutation (KO) in...
https://www.spandidos-publications.com/10.3892/mmr.2020.11331
Identification of a novel homozygous variant in the CNGA1 gene in a Chinese family with autosomal...
Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.
https://www.frontiersin.org/journals/dental-medicine/articles/10.3389/fdmed.2021.675130/full
Frontiers | A Novel Homozygous Variant in GJA1 Causing a Hallermann-Streiff/Oculodentodigital...
This paper reports the case of a Moroccan girl with a phenotype within the clinical spectrum of both Hallermann-Streiff (HSS, OMIM 234100) and Oculodentodigi...
a novelfrontiershomozygousvariant
https://www.frontiersin.org/journals/genetics/articles/10.3389/fgene.2025.1474390/full
Frontiers | Identification of a novel homozygous SLC13A5 nonstop mutation in a Chinese family with...
IntroductionBiallelic loss-of-function variants in the SLC13A5 (solute carrier family 13, member 5) gene are responsible for autosomal recessive developmenta...
https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2025.1517417/full
Frontiers | Case report: Novel multi-exon homozygous deletion of ZBTB24 causes immunodeficiency,...
Immunodeficiency, centromeric instability, and facial anomalies syndrome (ICF) is a rare genetic disease characterized by hypogammaglobulinemia, T cell immun...
case report
https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2022.1008937/full
Frontiers | Case report: Unusual episodic myopathy in a patient with novel homozygous deletion of...
We present a patient with unusual episodes of muscular weakness due to homozygous deletion of exon 2 in MICU1 gene. 43 patients from 33 families were previou...
https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2023.1160110/full
Frontiers | Case report: Hereditary spastic paraplegia with a novel homozygous mutation in ZFYVE26
Hereditary spastic paraplegia (HSP) is a group of neurodegenerative diseases with genetic and clinical heterogeneity characterized by lower limbs spasticity ...
hereditary spastic paraplegia
https://www.endocrine.org/journals/journal-of-the-endocrine-society/bmp15-mutation-causes-ovarian-dysgenesis
A Novel Homozygous BMP15 Mutation Causes Ovarian Dysgenesis and Primary Amenorrhea | Endocrine...
This work aims to study the genetic etiology causing absence of spontaneous pubertal development, hypergonadotropic hypogonadism, and primary amenorrhea in 2...
a novel
https://elifesciences.org/articles/30490
A homozygous FANCM mutation underlies a familial case of non-syndromic primary ovarian...
Bilallelic mutations of FANCM, a DNA-damage response gene whose heterozygous mutations predispose to breast cancer, are involved in a familial case of Primary...
https://4kraxfarm.com/
Registered Homozygous Polled Miniature Hereford Cattle Breeders - 4 Krax Farm
Discover 4 Krax Farm, premier Miniature Hereford Cattle Breeders. Quality cattle breeding with registered Herefords for sale. Book an appointment today!
hereford cattleregisteredhomozygouspolledminiature
https://www.frontiersin.org/journals/genetics/articles/10.3389/fgene.2023.1256549/full
Frontiers | Case report: A novel homozygous variant in ZP3 is associated with human empty follicle...
Empty follicle syndrome (EFS) is a rare condition in female infertility. It is characterized by the inability to retrieve oocytes from visibly large, normall...
https://www.wikidata.org/wiki/Q35570305
Homozygous familial hypercholesterolemia: specificity of the biochemical defect in cultured cells...
scientific article published on March 1974
familial hypercholesterolemiaof thehomozygousspecificity
https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2023.1105381/full
Frontiers | Case report: A rare homozygous variation in the ENPP1 gene, presenting with generalized...
Generalized arterial calcification of infancy (GACI) is a rare genetic disease characterized by arterial calcifications or stenoses and hypertension. GACI is...
https://www.hofhdisease.ca/
Homozygous Familial Hypercholesterolemia
Apr 26, 2025 - If you have extremely high levels of bad cholesterol (LDL-C), you might have What is HoFH? HoFH is a serious, lifelong, ultra-rare disease that is inherited...
homozygousfamilialhypercholesterolemia
https://www.wikidata.org/wiki/Q35053655
Microsurgically produced homozygous-diploid uniparental mice - Wikidata
scientific article published on December 1, 1977
producedhomozygousdiploidmicewikidata
https://www.sciencing.com/characteristics-homozygous-phenotype-20641/
What Are The Characteristics Of A Homozygous Phenotype?
Aug 30, 2022 - The true story lies in your genes. You may have brown eyes, or red hair, or long fingers. Many of your traits were inherited from your parents, but the exact...
characteristicshomozygousphenotype
https://elifesciences.org/articles/26129v1/peer-reviews
Peer review in FXR1 regulates transcription and is required for tumor growth in TP53 homozygous...
https://www.frontiersin.org/journals/genetics/articles/10.3389/fgene.2022.872836/full
Frontiers | Case Report: MYO5B Homozygous Variant c.2090+3AT Causes Intron Retention Related to...
Background: Biallelically mutated MYO5B is associated with microvillus inclusion disease (MVID, MIM: 251850), cholestasis, or both. This study aims at valida...